Clinico-pathological factors and [F]FDG PET/CT metabolic parameters for prediction of progression-free survival in radioiodine refractory differentiated thyroid carcinoma.

Objective: Identifying prognostic markers for clinical outcomes is crucial in selecting appropriate treatment options for patients with radioiodine-refractory (RAI-R) differentiated thyroid carcinoma (DTC). The aim of this study was to investigate the prognostic value of clinico-pathological features and semiquantitative [F]FDG PET/CT metabolic parameters in predicting progression-free survival (PFS) in DTC patients with RAI-R.

Patients And Methods: This prospective cohort study included 110 consecutive RAI-R DTC patients who were referred for [F]FDG PET/CT imaging.

Development and validation of a gonadotropin dose selection model for optimized ovarian stimulation in IVF/ICSI: an individual participant data meta-analysis.

Background: The ovarian response to gonadotropin stimulation varies widely among women, and could impact the probability of live birth as well as treatment risks. Many studies have evaluated the impact of different gonadotropin starting doses, mainly based on predictive variables like ovarian reserve tests (ORT) including anti-Müllerian hormone (AMH), antral follicle count (AFC), and basal follicle-stimulating hormone (bFSH). A Cochrane systematic review revealed that individualizing the gonadotropin starting dose does not affect efficacy in terms of ongoing pregnancy/live birth rates, but may reduce treatment risks such as the development of ovarian hyperstimulation syndrome (OHSS).

Quantifying rice dry biomass to determine the influence of straw burning on BC and NO emissions in the Hanoi metropolitan region.

The urban setting notwithstanding, rice cultivation prevails on the outskirts of Hanoi, with the burning of rice straw in the fields posing a significant challenge. Therefore, it is crucial to conduct spatial mapping of rice distribution, assess dry biomass, and determine emissions from rice straw burning within Hanoi city. The efficacy of the deep convolutional neural networks (DCNN) model has been evident in accurately mapping the spatial distribution of rice in Hanoi, where rice cultivation extensively thrives in suburban areas.

Artificial intelligence in pediatric allergy research.

Unlabelled: Atopic dermatitis, food allergy, allergic rhinitis, and asthma are among the most common diseases in childhood. They are heterogeneous diseases, can co-exist in their development, and manifest complex associations with other disorders and environmental and hereditary factors. Elucidating these intricacies by identifying clinically distinguishable groups and actionable risk factors will allow for better understanding of the diseases, which will enhance clinical management and benefit society and affected individuals and families.

Effectiveness and acceptability of a 24-h interval versus a 48-h interval between mifepristone intake and misoprostol administration for in-hospital abortion at 9-20 gestational weeks: an international, open-label, randomised, controlled, non-inferiority trial.

Background: Optimising management of second-trimester medical abortion is important, as complications increase with gestational age. We aimed to compare a 24-h interval with a 48-h interval between mifepristone intake and misoprostol administration in in-hospital, second-trimester medical abortion for effectiveness and acceptability.

Methods: This open-label, randomised, controlled, non-inferiority trial was conducted at nine hospitals in India, Sweden, Thailand, and Viet Nam among adults undergoing medical abortion for a singleton viable pregnancy at a gestation of between 9 weeks and 20 weeks.

Assessment of potential ecological risk for microplastics in freshwater ecosystems.

Microplastics (MPs) are one of the most widespread environmental pollutants, but their risk assessment to freshwater ecosystems has not been clearly investigated. Risk assessment has been constrained by the absence of MP concentration in some environment, the diverse types and shapes of MPs, and limitations of polystyrene (PS)-biased toxicity studies. This study examined exposure to MPs in rivers and lakes worldwide, including China (the Three Gorges Dam & Yangtze River (TGD & YR) and the lakes of Wuhan city (WL)), Vietnam (seven lakes of Da Nang city (7UL)), Europe (the Rhine River (RR)), Finland (Kallavesi Lake (KL)), Argentina (nine lakes in the Patagonia region (9LP)), Brazil (Guaiba Lake (GL)), and South Korea (Nakdong River (NR), Han River (HR), and Anyang Stream (AS)), and assessed the risks to aquatic ecosystems based on the toxicity information and morphology of MPs.

Sustainable antimicrobial resistance surveillance: time for a global funding mechanism.

Antimicrobial resistance (AMR) is predicted to outstrip malaria, HIV, and tuberculosis combined as the leading infectious cause of death by 2050. Strengthening the knowledge and evidence base for AMR with surveillance and research is one of the five main objectives of the WHO Global Action Plan on AMR. While recent efforts to strengthen diagnosis and surveillance have been encouraging, these are unlikely to be sustainable without continued funding support in most low-resource settings.

Formulation and optimization study of nanodelivery system encapsulating guava wild leaf extract for potential anti-inflammatory properties.

Psidium guajava L. (Myrtaceae) has long been used in folk medicine as a potent therapeutic agent for the treatment of inflammation. Despite its potential, the application of this natural source remains limited because of its instability and poor permeability through biological barriers.

Longitudinal changes in tenofovir and tenofovir-diphosphate concentrations among pregnant women using oral PrEP for HIV prevention: Findings from Durban, South Africa.

Background: Pregnant women are vulnerable to HIV acquisition. Oral HIV pre-exposure prophylaxis (PrEP) is safe and effective for use during pregnancy. We describe PrEP adherence among pregnant women using multiple measures.

Performance analysis of dual-hop mixed RF-FSO systems combined with NOMA.

This paper investigates the performance of hybrid radio frequency/free space optical (RF/FSO) systems combined with non-orthogonal multiple access communications technology. We examine a scenario where the source and destination are separated by a large distance, with no direct link between them. The relay, denoted R, operates using the decode-and-forward (DF) protocol.

Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function.

OSBP ligands from the ORPphilin family are chemically complex natural products with promising anticancer properties. Here, we describe macarangin B, a natural racemic flavonoid selective for OSBP, which stands out from other ORPphilins due to its structural simplicity and distinct biological activity. Using a bioinspired strategy, we synthesized both (,,) and (,,)-macarangin B enantiomers, enabling us to study their interaction with OSBP based on their unique optical properties.

Enhanced prediction of beta-secretase inhibitory compounds with mol2vec technique and machine learning algorithms.

A comprehensive computational strategy that combined QSAR modelling, molecular docking, and ADMET analysis was used to discover potential inhibitors for β-secretase 1 (BACE-1). A dataset of 1,138 compounds with established BACE-1 inhibitory activities was used to build a QSAR model using mol2vec descriptors and support vector regression. The obtained model demonstrated strong predictive performance (training set:  = 0.

Multivariable Analysis of Correlation Between Anatomical Features of Mandibular Third Molars and Pericoronitis.

The correlation between anatomy features of impacted mandibular third molars (M3Ms) and prevalence of pericoronitis was only interpreted using univariate analysis. This study investigated this correlation using multivariable analysis to determine the relationship between pericoronitis prevalence and the M3Ms' anatomical features. This cross-sectional study recruited 245 patients with 338 impacted M3Ms.

Tocilizumab for Cystoid Macular Edema Secondary to Immune Recovery Uveitis in a Patient with Contraindications to Long-Term Systemic Corticosteroid.

: To report a case of cystoid macular edema (CME) secondary to immune recovery uveitis (IRU) in a patient with previous history of cytomegalovirus (CMV) retinitis and leukemia, which was successfully treated with tocilizumab (TCZ), an interleukin-6 (IL-6) receptor antagonist. : The clinical records of the case were reviewed, focusing on demographics, image findings, and clinical course. : A 17-year-old female with a past medical history of T-cell acute lymphoblastic leukemia (T-ALL) undergoing chemotherapy for two years presented with active CMV retinitis.

Description of the larva of Hämäläinen, 2003 (Odonata, Platycnemididae), with a key to the larvae of the subfamily Platycnemidinae from the Sino-Japanese and Oriental regions.

The final instar larva of the rare species Hämäläinen, 2003 is described and illustrated here for the first time, including a new distribution record from Vietnam. The larva of differs from that of congeneric species by distinct morphological features, including the presence of four setae on the palpal lobe of the labium, the presence of lateral spines on abdominal S5-9, and a long terminal filament on the caudal lamella. We also provide a key to species for the known larvae of the subfamily Platycnemidinae in the Sino-Japanese and Oriental regions.

The impact of the COVID-19 pandemic in Malaysia, Indonesia, Thailand and Vietnam: insights from the SEANUTS II study.

Objective: To describe the economic, lifestyle and nutritional impact of the COVID-19 pandemic on parents, guardians and children in Malaysia, Indonesia, Thailand and Vietnam.

Design: Data from the SEANUTS II cohort were used. Questionnaires, including a COVID-19 questionnaire, were used to study the impact of the pandemic on parents/guardians and their children with respect to work status, household expenditures and children's dietary intake and lifestyle behaviours.

A Library of Seed@High-Entropy-Alloy Core-shell Nanocrystals With Controlled Facets for Catalysis.

High-entropy-alloy (HEA) nanocrystals hold immense potential for catalysis, offering virtually unlimited alloy combinations through the inclusion of at least five constituent elements in varying ratios. However, general and effective strategies for synthesizing libraries of HEA nanocrystals with controlled surface atomic structures remain scarce. In this study, a transferable strategy for developing a library of facet-controlled seed@HEA nanocrystals through seed-mediated growth is presented.

Investigating land cover changes and their impact on land surface temperature in Tay Ninh province, Vietnam.

Land surface temperature (LST) serves as a crucial indicator for evaluating the effects of different environmental factors on the ecosystem, including alterations in land use, climate variations, and emissions of greenhouse gases. This comprehensive study used remote sensing data to analyze changes and effects of land use/land cover (LULC) on LST in Tay Ninh province, Vietnam, from 1988-2023. Landsat satellite images in 1988, 2004, and 2023 were preprocessed and supervised classification on ArcGIS 10.

The Roles of Acculturation and Pre-migration Experiences in Influencing the Confidence of Vietnamese Parents in Vaccine Use Among Adolescents.

Vaccine confidence is a critical antecedent of vaccine uptake. Little research has examined vaccine confidence among Asian communities, particularly the associations with acculturation and pre-migration experiences. We explored this issue among U.

The interaction between values and self-identity on fairtrade consumption: The value-identity-behavior model.

The interplay between egoistic and altruistic values, self-identity, and ethical behaviors remains underexplored, despite its significance in ethical consumption. This study investigates these dynamics by developing and testing the Value-Identity-Behavior model using a robust dataset of 3023 participants from three leading fairtrade markets in Europe: the U.K.

This is MY earth: Hybrid meat's impact on psychological ownership.

Across two experimental studies, we examine the role of psychological ownership of the Earth and it's anthropomorphosis on hybrid meat purchase intentions as the result of proximal and distal message framing. Study 1 revealed that proximal (vs. distal) message framing (e.

Drug-loaded FeO/lignin nanoparticles to treat bacterial infections.

Lignin is a biopolymer employed for various biomedical applications. Nevertheless, the drug loading and release mechanism of FeO nanoparticles with surface functionalization by lignin has yet to be described. Hence, this study functionalizes FeO nanoparticles surface with lignin (FeO/Lig) for ciprofloxacin delivery and examines its adsorption-release mechanisms.

An upward trend of dyslipidemia among adult population in Vietnam: Evidence from a systematic review and meta-analysis.

Introduction: It is critical to assess the progress toward achieving the national goal of reducing premature mortality from non-communicable diseases (NCDs) by one-third by 2030 in Vietnam. This study aimed to examine the pooled prevalence of dyslipidemia among the Vietnamese adult population.

Method: Five databases, PubMed, Web of Science, Embase, CINAHL, Google Scholar, and local peer-reviewed journals were searched from inception to May 2024 without language restrictions.

Macrophage-hitchhiked, effervescence-induced nanoemulsions for enhanced oral chemotherapy and immunotherapy: Impact on absorption route.

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer. Paclitaxel (PTX), typically administered intravenously (IV) as chemotherapy, shows promise for triggering immunogenic cell death (ICD) and may serve as a potential immunotherapy. This study introduces an oral PTX delivery method using an enteric-coated gelatin capsule containing capric acid oil and an effervescent agent, optionally with decylamine-conjugated β-glucans (DA-βGlus).