246 results match your criteria: "Vibrio Vulnificus Infection"
Emerging -Associated Infections After Seawater Exposure-Cases from the Bulgarian Black Sea Coast.
Medicina (Kaunas)
October 2024
Department of Microbiology and Virology, Medical University of Varna, 9002 Varna, Bulgaria.
Article Synopsis
Vibrio vulnificus infection complicated by acute-on-chronic liver failure: A case report.
Medicine (Baltimore)
October 2024
Department of Emergency, The First Affiliated Hospital of Hainan Medical University, Haikou, China.
Article Synopsis
- Vibrio vulnificus is a harmful bacterium that can cause severe health issues, including gastrointestinal problems and liver failure, especially in people with pre-existing liver conditions.
- A 56-year-old man developed acute liver failure after an injury from a machete that had been used to cut seafood; testing revealed V vulnificus in his blood.
- Treatment with a double plasma molecular adsorption system improved his liver function, highlighting the need for prompt care in patients with a history of liver disease when faced with V vulnificus infections.
Novel Vibrio vulnificus sequence type 540 infection in a hepatitis patient.
Trop Biomed
June 2024
Tropical Infectious Diseases Research & Education Centre, Higher Institution Centre of Excellence, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.
Article Synopsis
- Vibrio vulnificus is a dangerous bacterium that can cause severe infections, particularly in patients with underlying health issues, leading to high mortality rates, sometimes over 50%.
- A case study highlighted a cirrhotic patient with hepatitis C who experienced abdominal pain, fever, and tea-colored urine, ultimately diagnosed with V. vulnificus bacteremia after blood tests confirmed the infection.
- The patient was treated successfully with intravenous cefoperazone, followed by oral ciprofloxacin, emphasizing the importance of early diagnosis and treatment, as well as the need for bacterial typing to monitor infection spread and virulence.
In vivo examination of pathogenicity and virulence in environmentally isolated Vibrio vulnificus.
Microbiologyopen
August 2024
Department of Biological Sciences, University of South Carolina, Columbia, South Carolina, USA.
Article Synopsis
- Human exposure to Vibrio vulnificus, a dangerous bacteria found in certain environments, is on the rise, leading to severe infections with high hospitalization and mortality rates.
- The study aims to uncover how different strains of V. vulnificus vary in their ability to cause disease, using zebrafish as a model for investigation.
- Results indicate that virulence differs significantly among strains, highlighting that genetic markers don't reliably predict how severe an infection might be.
The cytochrome P4501A1 (CYP1A1) inhibitor bergamottin enhances host tolerance to multidrug-resistant Vibrio vulnificus infection.
Chin J Traumatol
September 2024
The College of Emergency and Trauma, Hainan Medical University, Haikou, 571199, China; The First Research Department, State Key Laboratory of Trauma and Chemical Poisoning, Army Medical Center (Daping Hospital), Army Medical University, Chongqing, 400042, China. Electronic address:
Article Synopsis
The role of MNK1-mTORC1 pathway in modulating macrophage responses to infection.
Microbiol Spectr
August 2024
Department of Immunology and Pathogenic Biology, School of Medicine, Xi'an Jiaotong University, Xi'an, Shanxi, China.
Article Synopsis
- The study investigates the role of mitogen-activated protein kinase (MNK) in macrophages during infections, particularly focusing on its influence on pro-inflammatory cytokine production and macrophage function.
- Inhibition of MNK in macrophage cells led to reduced production of key cytokines, tumor necrosis factor alpha and interleukin-6, without altering their transcription levels, while knockout of MNK1 improved the cells' ability to digest and eliminate bacteria.
- The research also found that MNK1's effects on phagocytosis and bacterial clearance are linked to the mTORC1 signaling pathway rather than the MNK1-eIF4E pathway, emphasizing the MNK1-m
infection from insect bites in Shanghai: a case report.
Front Med (Lausanne)
June 2024
Department of Traditional Chinese Surgery, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Article Synopsis
- Infection linked to a specific pathogen is increasing due to climate change, leading to more severe cases and higher amputation and death rates.
- A 75-year-old man in a coastal city developed this infection after being bitten by an insect.
- The case highlights the need for doctors to quickly identify and treat such infections with the right antibiotics to lower the risks of amputation and death.
Virulent properties and genomic diversity of isolated from environment, human, diseased fish.
Microbiol Spectr
July 2024
Division of Biological Science, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla, Thailand.
Article Synopsis
- The study highlights a rise in infections with high mortality rates in humans and aquatic animals, identifying a need for better markers to assess the virulence of pathogenic strains.
- The research analyzed different strains from various sources, revealing that while some environmental isolates exhibit unique genetic traits, clinical strains show stronger virulence-associated characteristics.
- Genetic analysis uncovered significant diversity among strains and emphasized that there isn't a clear link between their genetic makeup and virulence, suggesting the importance of managing risks from environmental pathogens.
Sensitive colorimetric detection of Vibrio vulnificus based on target-induced shielding against the peroxidase-mimicking activity of CeO@PtRu nanozyme.
Food Chem
October 2024
Department of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, People's Republic of China. Electronic address:
Article Synopsis
- Vibrio vulnificus, found in contaminated seafood and seawater, can cause serious infections and high death rates, highlighting the need for effective detection methods.
- A new detection method using a colorimetric immunoassay with CeO@PtRu showed rapid and sensitive results for identifying Vibrio vulnificus, operating effectively within a specific detection range.
- This biosensor demonstrated excellent specificity and recovery rates, making it a promising tool for sensitive monitoring of Vibrio vulnificus in seafood.
Successful recovery of a patient with a pronounced Vibrio vulnificus infection: A case report.
Asian J Surg
August 2024
Department of Plastic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China. Electronic address:
[Clinical characteristics of 11 patients with infection and the establishment of a rapid diagnosis procedure for this disease].
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi
March 2024
Department of Burns and Wound Repair, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China.
Article Synopsis
- The study analyzed the clinical characteristics and treatment of 11 patients with infection at a hospital in Guangdong Province, focusing on establishing a rapid diagnosis procedure.
- Data collected included demographics, clinical manifestations, laboratory results, and treatment methods, with a retrospective review spanning from January 2009 to November 2022.
- The findings showed most patients were middle-aged males, with symptom onset commonly in summer and autumn, and highlighted the importance of timely diagnosis and treatment, particularly in those exposed to seawater or marine products.
infection from tilapia sting wounds in an inland city: A case report.
Heliyon
March 2024
Affiliated Hospital of Panzhihua University, Panzhihua, China.
Article Synopsis
- A pathogen linked to serious infections, particularly from sea contact, is increasingly affecting non-coastal regions due to climate change and seafood trade.
- The report details a successful case of necrotizing wound treatment in an inland city in southwest China caused by this pathogen.
- It also reviews the epidemiology of the pathogen in China and highlights ongoing vaccine research to aid in diagnosis and treatment.
Case Report: First case of HIV, hepatitis B, hepatitis C, and Vibrio vulnificus coinfection.
Front Cell Infect Microbiol
December 2023
Institute of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Article Synopsis
- A 48-year-old man from Guangdong experienced painful swelling in his left knee, leading to hospitalization due to a Vibrio vulnificus infection while he had concurrent AIDS and hepatitis A and B.
- Despite worsening symptoms and potential amputation, his family opted to save the limb, and he received intensive care with wound management and antibiotic treatments.
- By November 1, the patient's condition improved, showing significant healing with new granulation tissue covering 80% of the wound and restored organ function.
Enhancing infection diagnosis for negative culture patients with metagenomic next-generation sequencing.
Front Cell Infect Microbiol
December 2023
Department of Infectious Diseases, The Fifth Affiliated Hospital of Sun Yet-sun University, Zhuhai, China.
Article Synopsis
- - The study aimed to assess how effective metagenomic next-generation sequencing (mNGS) is in diagnosing infections related to marine trauma at a hospital in Zhuhai, analyzing data from 14 patients over a 3-year period.
- - Most patients (78.6%) had marine-related injuries, while infections were confirmed through a combination of culture and mNGS methods, with a significant recovery rate following surgical intervention and antibiotic treatment.
- - The findings highlight that mNGS is valuable for diagnosing water-exposed infections and can help identify multiple pathogens, improving treatment guidance for severe infections with unknown causes.
Evidence that fish death after Vibrio vulnificus infection is due to an acute inflammatory response triggered by a toxin of the MARTX family.
Fish Shellfish Immunol
November 2023
Instituto Universitario de Biotecnología y Biomedicina (BIOTECMED), Universitat de València, Dr. Moliner, 50, 46100, Valencia, Spain. Electronic address:
Article Synopsis
- Vibrio vulnificus is a harmful pathogen found in fish farms that causes a severe illness called warm-water vibriosis, leading to high fish mortality.
- Recent studies indicate that fish deaths are more closely linked to the host's inflammatory response rather than direct damage from the pathogen itself.
- The RtxA1 toxin is suggested as a major factor in triggering this harmful inflammatory response, with research showing that fish infected with a mutant lacking RtxA1 can survive despite still being able to invade and colonize.
P2X7 receptor blockade reduces pyroptotic inflammation and promotes phagocytosis in Vibrio vulnificus infection.
J Cell Physiol
October 2023
Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan.
Article Synopsis
- Vibrio vulnificus is a harmful bacterium that can lead to severe infections, including sepsis, where an overactive immune response often worsens patient outcomes.
- The study investigates how V. vulnificus affects immune cells, specifically showing that it triggers inflammation and impairs the ability of macrophages to engulf pathogens through a specific receptor called P2X7R.
- Researchers found that blocking P2X7R not only reduces inflammation and the spread of the bacteria in mice but also offers potential new treatment strategies for infections caused by V. vulnificus.
Clinical features and treatment outcomes of infection in the coastal city of Ningbo, China.
Front Microbiol
July 2023
Department of Clinical Laboratory, The First Affiliated Hospital of Ningbo University, Ningbo First Hospital, Ningbo, China.
Article Synopsis
- The study investigates rare but severe infections caused by a gram-negative pathogen, particularly affecting those in coastal areas during summer, often leading to rapid health decline and high mortality rates.
- Researchers reviewed medical records of six male patients with existing liver conditions who developed sepsis from the infection, two having consumed seafood prior to symptoms.
- Out of the six patients, four died, two recovered, and one required leg amputation, emphasizing the need for quick and aggressive treatment in at-risk populations, especially older adults with liver issues.
Meteorological associations of Vibrio vulnificus clinical infections in tropical settings: Correlations with air pressure, wind speed, and temperature.
PLoS Negl Trop Dis
July 2023
Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, United States of America.
Article Synopsis
- * A study examined 448 cases in Florida from 2008 to 2020, focusing on how meteorological factors, like water and air temperature, wind speed, and sea-level pressure, are linked to the incidence of infections and related deaths.
- * The research found that infections peaked in 2017 and that higher temperatures and lower wind speeds correlated with increased cases and fatalities, suggesting that weather conditions may significantly affect public health regarding this pathogen.
A case report of sepsis in a diabetic patient.
Heliyon
June 2023
Department of Emergency, Nantong Third People's Hospital, Affiliated Nantong Hospital 3 of Nantong University, Nantong, 226001, Jiangsu, China.
Article Synopsis
- The text discusses an 85-year-old male patient who developed a severe infection caused by a facultative anaerobic, halophilic, Gram-negative bacterium after being stabbed by a sea shrimp, complicating his existing diabetes and alcoholism.
- The patient’s condition worsened rapidly due to the bacterial infection and his underlying health issues, but timely diagnosis using next-generation sequencing and blood cultures allowed for targeted antibiotic treatment.
- The paper highlights the importance of understanding the epidemiology, symptoms, diagnosis, and treatment of such infections, providing guidance for clinicians dealing with similar cases, especially in diabetic patients exposed to seafood.
Vibrio vulnificus pneumonia with multiorgan failure: a case report and review of the literature.
J Med Case Rep
May 2023
Medical Intensive Care Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka.
Article Synopsis
- Vibrio vulnificus is a harmful bacterium that can cause severe health issues, especially primary sepsis with high mortality rates, particularly in immunocompromised individuals, and is usually transmitted through contaminated seafood or seawater.
- A case study describes a healthy 46-year-old man who developed an unusual Vibrio vulnificus infection leading to severe pneumonia, despite showing no typical gastrointestinal or skin symptoms.
- The patient faced significant challenges during his treatment, including respiratory failure requiring intubation and complications like acute kidney injury, but ultimately recovered after a prolonged ICU stay and targeted antibiotic therapy.
Pathogenic mechanism of infection.
Future Microbiol
April 2023
Department of Neurosurgery, First Naval Hospital of Southern Theater Command, Zhanjiang, 524000, China.
Article Synopsis
- The text discusses a fatal pathogen that humans can contract by eating raw or undercooked seafood or through direct skin contact, leading to severe, rapid infections that may result in amputation or death.!* -
- The role of virulence factors and regulators in the infection process is highlighted, including their impact on host resistance, cellular damage, iron acquisition, and immune response, although the exact mechanisms are not fully understood.!* -
- The review emphasizes the need for further research into the pathogenesis of this infection to improve prevention and treatment strategies for those affected.!*
Climate warming and increasing Vibrio vulnificus infections in North America.
Sci Rep
March 2023
School of Environmental Sciences, University of East Anglia, Norwich, Norfolk, UK.
Article Synopsis
- Vibrio vulnificus is a dangerous bacteria found in warm ocean waters that can cause serious wound infections, especially for people who get cut while swimming.
- Cases of these infections in the Eastern USA have increased a lot over the past 30 years, and researchers predict even more cases in the future due to climate change and more people living nearby.
- By the years 2041-2060, this bacteria might spread to areas with lots of people, so it's important for everyone to be aware and take care when they're near the ocean.