Case report: Clinical and immunohistochemical manifestations of suspected Sjogren's disease in a dog.

Sjogren's disease, well-described in people, is rarely identified in veterinary species. In people, Sjogren's disease is one of the most common systemic autoimmune disorders with an incidence of 0.5% in the female population.

Development of a sensitive disease-screening model using comprehensive circulating microRNA profiles in dogs: A pilot study.

In the veterinary field, the utility of disease-identification models that use comprehensive circulating microRNA (miRNA) profiles produced through measurements based on next-generation sequencing (NGS) remains unproven. To integrate NGS technology with automated machine learning (autoML) to create a comprehensive circulating miRNA profile and to assess the clinical utility of a disease-screening model derived from this profile. The study involved dogs diagnosed with or being treated for various diseases, including tumors, across multiple veterinary clinics ( = 254), and healthy dogs without apparent diseases ( = 91).

Serum amikacin concentrations in dogs with naturally occurring open wounds treated with topical amikacin in carboxymethylcellulose hydrogel.

Objective: To quantify serum amikacin concentrations in dogs undergoing wound management with topical amikacin (45 mg/mL) 3% carboxymethylcellulose hydrogel.

Study Design: Prospective clinical study.

Sample Population: Eleven client-owned dogs.

Patient-specific 3D-printed nasopharyngeal stents in dogs: a cadaveric pilot study.

Background: Currently available treatment options for nasopharyngeal stenosis and imperforate nasopharynx in dogs and cats are fraught with complications and failures.

Objective: To develop patient-specific nasopharyngeal stents using 3D-printed molds and to assess placement and fit of stents within the nasopharynx.

Animals: Six canine cadavers.

A clinical and hematologic approach to basophilia in dogs, cats, and horses.

Background: Basophils are the rarest blood leukocyte in most healthy domestic mammals and the clinical significance of basophilia is poorly understood.

Objectives: To empirically determine magnitude thresholds for basophilia, identify its hematologic correlates, and identify associations between breeds, specific diseases, disease categories, organ systems, and basophilia in dogs, cats, and horses.

Methods: CBCs and clinical information from dogs, cats, and horses were collected from the University of California-Davis School of Veterinary Medicine between 2000 and 2020.

Amyloid-producing ameloblastoma of the maxilla in a 17-year-old cynomolgus macaque (Macacafascicularis).

Amyloid-producing ameloblastomas (APAs) are a histological variant of ameloblastoma in which the neoplastic odontogenic epithelial cells are associated with the production of amyloid. This jaw-associated entity has been only rarely described in animals and purportedly does not exist in humans. This report is the first description of an APA in a primate.

Evaluation of three acetabular measurement methods for total hip replacement in dogs.

Objective: To compare three measurement methods for acetabular sizing and evaluate the influence of osteoarthritis (OA) on the accuracy of measurements.

Study Design: Observational study.

Sample: Radiographic images of 73 hip joints from 60 dogs with cementless cups.

Diversity of spp. circulating in a rhesus macaque () breeding colony using culture and molecular methods.

Unlabelled: and represent the leading causes of bacterial gastroenteritis in humans, and infections can produce post-infectious irritable bowel syndrome (PI-IBS). Rhesus macaques () (RM) are similarly susceptible to acute campylobacteriosis and represent a potential model of PI-IBS. We characterized the species circulating in an RM breeding colony using culture, qPCR, and whole genome sequencing (WGS).

Effect of furosemide on comprehensive renin-angiotensin-aldosterone system activity of Thoroughbred horses.

Background: Furosemide, a commonly used diuretic, activates the renin-angiotensin-aldosterone system (RAAS) in other species. Little is known about RAAS peptide activation in horses.

Hypothesis/objectives: To evaluate equilibrium analysis as a practical method for RAAS quantification in horses and describe the RAAS response to a single dose of furosemide.

Replication kinetics and cytopathic effect of feline calicivirus in feline corneal epithelial cells.

Objective: To determine the replication kinetics and cytopathic effect (CPE) of feline calicivirus (FCV) in feline corneal epithelial cells (FCEC).

Animals Studied: Seven archived FCV isolates and one archived feline herpesvirus type 1 (FHV-1) isolate, previously obtained from eight domestic short hair cats.

Procedures: FCV RNA was extracted for sequencing using Illumina MiSeq, to identify three genomically diverse isolates for further testing.

Ultrasound-guided trigeminal nerve approach at the level of the pterygopalatine fossa in cat cadavers.

Objective: To describe an ultrasound-guided suprazygomatic approach to the trigeminal nerve block in cat cadavers.

Study Design: Prospective descriptive study.

Animals: Ten feline cadaver heads.

Contrast computed tomography dacryocystorhinography identifies nasolacrimal duct obstruction secondary to chronic dental disease in two chinchilla langeria.

Objective: To determine the impact of chronic dental disease on the nasolacrimal duct of chinchillas using contrast CT dacryocystorhinography.

Animals Studied: Two 12-year-old female chinchillas with uni- or bilateral ocular discharge and a history of chronic, moderate (Chinchilla 1, one-year) or severe (Chinchilla 2, three-years) dental disease.

Procedures: Contrast CT dacryocystorhinography was performed to identify abnormalities in the nasolacrimal duct and dentition, and to correlate those changes.

Diurnal variation of serum phosphorus concentrations in intact male adult domestic cats.

Background: Monitoring serum phosphorus concentrations is crucial in the management of chronic kidney disease in cats. The diurnal variation of serum phosphorus concentration may affect clinical assessment.

Hypothesis/objectives: Characterize the diurnal variation of serum phosphorus concentration in cats and determine the associations between changes in serum phosphorus concentration and several metabolites of phosphorus metabolism.

Computed tomographic findings of nasal and paranasal disease in domestic rabbits highlight maxillary sinusitis and close association with dental disease: 100 studies (2004-2024).

Objective: To describe CT findings and epidemiologic features of nasal and paranasal disease of rabbits (Oryctolagus cuniculus).

Methods: An electronic search was performed for rabbits that underwent skull CT from 2004 to 2024 and had findings consistent with nasal/paranasal or maxillary dental disease. History, signalment, and physical examination findings were recorded and reevaluated retrospectively for evidence of changes to the nasal passages, paranasal sinuses, and nearby associated anatomy.

Updates on Radiation Therapy for Pituitary Tumors: Techniques and Prognosis.

Radiation therapy for the treatment of both functional and nonfunctional pituitary tumors for dogs and cats has been described in veterinary medicine with a recent shift in focus toward stereotactic techniques. While the technology required and normal tissue constraints for stereotactic procedures are more stringent, recent publications indicate that, while it helps alleviate clinical signs, the survival response may not be as durable as with conventionally fractionated radiation therapy in dogs, despite being seen in cats. Regardless of the protocol recommendation, potential benefit to the patient is excellent with manageable side effect profiles.

Tumor Grade and Mitotic Count Are Prognostic for Dogs with Cutaneous Mast Cell Tumors Treated with Surgery and Adjuvant or Neoadjuvant Vinblastine Chemotherapy.

Objective: Canine cutaneous mast cell tumors (cMCTs) have variable rates of recurrence and metastasis. We evaluated how various prognostic factors affect survival, recurrence, and metastasis in dogs with cMCT who underwent surgery and vinblastine chemotherapy.

Animals: 90 dogs with cMCT treated with surgery and vinblastine at a veterinary referral institution were included.

Parasternal thoracotomy via sternocostal disarticulation: a novel surgical approach to the canine thorax.

Objective: To describe the technique and outcomes of a modified paramedian thoracic approach in dogs involving a parasternal thoracotomy via rib disarticulation at the sternocostal joint.

Animals: 93 client-owned dogs.

Methods: Medical records of dogs that underwent parasternal thoracotomy at a private practice between the years 2015 and 2021 were reviewed.

Disseminated granulomatous encephalitis caused by Schizophyllum commune in a dog with severe neurological signs.

A 10-year-old spayed mixed breed dog presented with severe neurological signs. Computed tomography revealed a cranial mediastinal mass, osteolysis of the right second rib and second thoracic vertebra, tracheobronchial and mesenteric lymph node enlargement, pneumonia and pleural effusion. Magnetic resonance imaging detected lesions in the white matter of the right frontal lobe and left cerebral hemisphere with contrast-enhanced T1-weighted images showing demarcated enhancement.

Sequence typing of Bartonella henselae in small Indian mongooses (Urva auropunctata).

This study aimed to determine the sequence type (ST) of Bartonella henselae infecting small Indian mongooses from Saint Kitts via multi-locus sequence typing (MLST). This investigation used stored EDTA blood (n = 22) samples from mongooses previously identified as positive for B. henselae.

A novel electroencephalographic evaluation of noxious stimulation during isoflurane anesthesia in dogs.

In veterinary clinical medicine, evaluating the balance between nociception and antinociception presents a great challenge for anesthesiologists during canine surgeries. Heart rate (HR) and mean arterial pressure (MAP) are suitable indexes for monitoring noxious stimuli during anesthesia. Frontal electroencephalography (EEG) records, including processed parameters, are recommended for evaluating nociceptive balance in anesthetized unconscious human patients, which is unexplored in veterinary medicine.

Neurodegeneration in a domestic rabbit with severe malnourishment and low hepatic copper.

Copper is a trace element that plays an essential role in neurodevelopment and neurologic function. Acquired copper deficiency has a range of neurologic manifestations, with myelopathy being the most common association. We describe here the clinical, radiologic, histopathologic, and toxicologic findings of a rabbit with malnutrition, neurodegeneration, and suspected copper deficiency.

Correlation between change in serum creatinine concentration and renal cortical anisotropic backscattering artifact in azotemic cats during hospitalization.

Information on the clinical outcomes of feline azotemia using ultrasound examinations is limited. This study aimed to understand the correlation between cortical anisotropy backscattering artifact (CABA) and serum creatinine (sCr) changes in feline azotemia after hospitalization and to investigate whether CABA is useful for predicting the clinical outcome of feline azotemia. Sixty-five hospitalized cats with azotemia, including 49 cats with moderate or severe azotemia (severe group) and 16 cats with mild azotemia (mild group).

Reproductive Tract Microbiota of Mares.

The female reproductive tract microbiota is a complex community of microorganisms that might be crucial in maintaining a healthy reproductive environment. Imbalances in the bacterial community (dysbiosis) and the reduction of beneficial organisms and pathogen proliferation are associated with disease. Endometritis is a common cause of fertility problems in mares, and it is still challenging to diagnose and treat based on routine culture results of certain microorganisms.