Incidence of Occupational Injuries Among Military Working Dog Handlers, 2016-2023.

Objective: This study examines the incidence of injuries among active component service members in Military Working Dog (MWD) handler occupations compared to three other active component occupational groups.

Methods: A retrospective cohort study was conducted with a total of 2,524,092 active component service members including, 3935 MWD handlers, 2025 veterinary personnel, 113,413 military police, and 2,404,719 all other active component service members (ACSM). Incidence rate and incident rate ratios of injuries were determined.

Perception and utilisation of veterinary services by rodent owners in the United Kingdom.

Background: There is limited research on how rodent owners use and perceive veterinary services and what the demand for pet insurance for these species is.

Methods: An online survey of owners of pet rodents (guinea pigs, hamsters, rats, gerbils and mice) measured owner confidence in recognising signs of illness, their opinions on and use of veterinary services and their willingness to purchase pet insurance.

Results: A total of 1700 respondents completed the survey.

Short-term evaluation of renal biochemical parameters in dogs completing chemotherapy for lymphoma.

Objectives: To identify if chemotherapeutic drugs in the CHOP-based protocol led to an increase in renal parameters in dogs with lymphoma during therapy and investigate whether factors such as prednisolone use or age affected this result.

Methods: Data were obtained retrospectively from private referral practice records of dogs diagnosed with lymphoma receiving a CHOP-based chemotherapy protocol between 2015 and 2019. Dogs included received a CHOP-based protocol as their first treatment, received four full cycles and were in remission at the end of the protocol.

Exploring the popularity of raw meat-based diets for dogs and cats: A cross-sectional opinion survey in Spain.

Background: Research on the general public's knowledge and usage patterns of pet food, particularly regarding raw meat-based diets (RMBDs), is limited in many countries, including Spain.

Methods: An anonymous cross-sectional web-based survey was conducted to assess the Spanish population's understanding and perceptions of RMBDs for cats and dogs.

Results: Of the 712 respondents, 46.

Assessment of tree-associated atypical myopathy risk factors in Acer pseudoplatanus (sycamore) seeds and leaves.

Background: Sycamore tree-derived hypoglycin A (HGA) toxin causes atypical myopathy (AM), an acute, equine pasture-associated rhabdomyolysis but incidence fluctuates.

Objectives: Investigate whether tree or environmental factors influence HGA concentration in sycamore material and are associated with AM relative risk.

Study Design: Retrospective and experimental prospective study.

Spatial and temporal analyses of Dermacentor variabilis (Say) (Acari: Ixodidae) in central and eastern Canada.

Dermacentor variabilis (Say) (Acari: Ixodidae) is a vector for pathogens that can impact human and animal health. The geographic range of this species is expanding, but there are some areas with limited up-to-date information on the distribution of D. variabilis.

First evidence of the effectiveness of a field application of RNAi technology in reducing infestation of the mite Varroa destructor in the western honey bee (Apis mellifera).

Background: The mite Varroa destructor is the most serious pest of the western honey bee (Apis mellifera) and a major factor in the global decline of colonies. Traditional control methods, such as chemical pesticides, although quick and temporarily effective, leave residues in hive products, harming bees and operators' health, while promoting pathogen resistance and spread. As a sustainable alternative, RNA interference (RNAi) technology has shown great potential for honey bee pest control in laboratory assays, but evidence of effectiveness in the field has been lacking.

Nutraceutical Impact of Pumpkin Seed Oil on Expression Levels of EZH-2 and KRT-14 Genes against DSS-induced Inflammatory Bowel Disease in the Rat Model.

Inflammatory bowel disease is a collection of intestinal disorders that cause inflammation in the digestive tract. Prolonged inflammation in the gastrointestinal tract is a major risk factor for colorectal cancer. The objective of this study was to fucus on gene expression levels of (KRT-14; associated with epithelial cell integrity) and enhancer of zeste homolog-1 (EZH-2; involved in cellular proliferation) in a IBD rat model in order to rule out impact of nutraceuticals (pumpkin seed oil; PSO) as a complementary approach to conventional treatments of IBD.

Effects of different environmental enrichment tools to improve behavior, welfare, and growth performance of broiler chickens.

This study was performed to evaluate the effect of various environmental enrichment (EE) tools on broiler growth, welfare, behavior, carcass, and meat quality. A total of 300 commercial broilers were randomly divided into 05 treatments. The treatments include various EE tools such as perches, balls, hanging bottles, and laser lights placed for birds and a control group.

Evaluating solar power plant sites using integrated GIS and MCDM methods: a case study in Kermanshah Province.

This study utilizes an integrated Geographic Information System (GIS)-based Multi-Criteria Decision-Making (MCDM) approach to perform Solar Power Plant Site Selection (SPPSS) in Kermanshah Province, Iran. It introduces a novel group weighting method, the Dempster-based Best-Worst Method (DBWM), which combines weights vectors derived from experts' opinions. The study also conducts a comprehensive sensitivity analysis comparing four GIS-based models for SPPSS.

Tailoring and characterization of bioactive graft material for alveolar bone preservation and regeneration in fresh extraction sockets of dog model.

The objective of this study was to tailor an osteoinductive scaffold for alveolar bone regeneration and around immediately placed implants in extraction sockets of dogs. Tailored amorphous multiporous bioactive glass (TAMP -BG) was prepared and characterized for bioactivity and response of human alveolar bone marrow mesenchymal stem cells (hABMSCs). Extraction sockets of twenty-two male mongrel dogs received TAMP-BG in the right side around implant in the distal socket of the mandibular fourth premolar (P4), while the adjacent empty mesial socket of the same tooth was filled with the same graft.

Involvement of TGF-β, mTOR, and inflammatory mediators in aging alterations during myxomatous mitral valve disease in a canine model.

Inflammaging, a state of chronic low-grade inflammation associated with aging, has been linked to the development and progression of various disorders. Cellular senescence, a state of irreversible growth arrest, is another characteristic of aging that contributes to the pathogenesis of cardiovascular pathology. Senescent cells accumulate in tissues over time and secrete many inflammatory mediators, further exacerbating the inflammatory environment.

Precision of stereophotogrammetry in complete arch implant recordings: A clinical study.

Statement Of Problem: Stereophotogrammetry has been proposed as an alternative to intraoral scanners for recording the location of multiple dental implants. Most studies evaluating its accuracy have been in vitro, and clinical studies are lacking.

Purpose: The purpose of this clinical study was to evaluate the precision of a stereophotogrammetry system for complete arch prostheses supported by 6 implants.

Treatment with a superoxide dismutase mimetic for joint preservation during 35 and 75 days in orbit aboard the international space station, and after 120 days recovery on Earth.

Reduced weight-bearing during spaceflight has been associated with musculoskeletal degradation that risks astronaut health and performance in transit and upon reaching deep space destinations. Previous rodent experiments aboard the international space station (ISS) have identified that the spaceflight-induced molecular arthritic phenotype was characterized with an increase in oxidative stress. This study evaluated if treatment with a superoxide dismutase (SOD) mimetic on orbit could prevent spaceflight-induced damage to the knee and hip articular cartilage, and the menisci in rodents.

Space biological and human survival: Investigations into plants, animals, microorganisms and their components and bioregenerative life support systems.

Space life science has been a frontier discipline in the life sciences, aiming to study the life phenomena of earth organisms and their activity patterns under the special environment of space. This review summarizes studies in various key topics in space life science, namely, how microbiome changes in humans and plants, the development of space agriculture and the use of animal, plant and cell models to study the effect of space environments on physiology. We highlight the new possibilities of using high-quality protein crystals uniquely available when grown under space conditions to aid drug development on earth, and the state-of-the-art Bioregenerative Life Support Systems (BLSS) to achieve long term human survival in space.

Geographical variation in antimicrobial resistant Salmonella Schwarzengrund from chicken meat in Japan.

Chicken meat is a major source of foodborne salmonellosis. In Japan, fluoroquinolones and third-generation cephalosporins are the first- and second-choice treatments for Salmonella gastroenteritis, respectively. We investigated the prevalence and antimicrobial resistance of Salmonella in 154 chicken meat products from Hokkaido (42), Tohoku (45), Kanto (5), and Kyushu (62), Japan.

Evaluation of a novel modified selective medium cefixime-tellurite-phosphate-xylose-rhamnose MacConkey agar for the isolation of Escherichia albertii from diarrheal stool specimens.

It is challenging to isolate Escherichia albertii from clinical specimens. Therefore, a medium that can selectively grow E. albertii and differentiate it from E.

Bacteriophage M13KE as a Nanoparticle Platform to Display and Deliver a Pathogenic Epitope: Development of an Effective Porcine Epidemic Diarrhoea Virus Vaccine.

Porcine epidemic diarrhoea virus (PEDV) is a porcine enteric coronavirus, outbreaks and epidemics of which have caused huge economic losses to the livestock industry. The disadvantage of existing PEDV vaccines is that the unstable efficacy and high cost limit their widespread use. Therefore, there is an urgent need to develop a recombinant transgenic vaccine candidate for PEDV.

Isolation, identification, and pathogenicity of a goose astrovirus 1 strain from goslings in Jiangsu province, China.

Goose astrovirus (GAstV) poses a large threat to the goose industry in China, with two genotypes: goose astrovirus genotype 1 (GAstV-1) and GAstV-2. GAstV-2 causes gout in goslings; however, understanding of GAstV-1 is limited. In this study, the GAstV-1 strain JY202323, was isolated from dead goslings, and its complete genome sequence was obtained using next-generation sequencing.

Protective effect of curcumin-loaded zeolitic imidazolate framework-8-based pH-responsive drug delivery system against Staphylococcus aureus infection.

Mastitis, generally caused by pathogenic microorganisms, is a serious disease in dairy farming. Staphylococcus aureus (S. aureus) is one of the main pathogens that induces mastitis in dairy cows.

Modelling the human Coenzyme Q deficiency in Drosophila melanogaster.

The interference of the expression of each of the genes involved in the synthesis of coenzyme Q (CoQ) in Drosophila melanogaster can help to understand the pathophysiology of CoQ-dependent mitochondrial diseases in humans. We have knocked-down all genes involved in the CoQ biosynthesis pathway at different temperatures to induce depletion of CoQ at different levels throughout the body and in a tissue-specific manner. The efficiency of the knockdowns was quantified by Q-RTPCR and determination of CoQ levels by HPLC-UV+ECD.

Nation-wide surveillance of ticks (Acari: Ixodidae) on dogs and cats in Singapore.

Companion animals are major reservoirs of zoonotic parasites and pathogens. Among these, ticks and tick-borne pathogens are of particular concern. Efforts to study the zoonotic risks associated with companion animals in Singapore have been hampered by a poor understanding of the ticks of local dogs and cats.

A novel ENTH domain-containing protein TgTEPSIN is essential for structural maintenance of the plant-like vacuolar compartment and bradyzoite differentiation in toxoplasma gondii.

Toxoplasma gondii is an intracellular and parasitic protozoon that harbors specialized cellular structures and molecular mechanisms, including the Plant-like Vacuolar Compartment (PLVAC). The PLVAC performs multifaceted roles in the parasite, contributing to ion homeostasis, proteolysis, pH regulation, and autophagy. Despite significant efforts over the past decade to characterize the PLVAC, the proteins localized to this organelle remain largely unidentified.

Comprehensive Analysis of Apigetrin's Effects on Liver Cancer Cells: Insights from Bioinformatics, In Vitro Studies, and Next-Generation Transcriptome Sequencing.

Despite numerous attempts to understand the molecular mechanisms behind the development of liver cancer, it continues to pose a significant worldwide health challenge. Transcriptome sequencing, a powerful tool in molecular biology, has played a pivotal role in uncovering the intricate gene expression profiles underlying hepatocellular carcinoma (HCC). In the present study, we identified a total of 808 differentially expressed genes (DEGs), with 584 exhibiting downregulation, and 224 showing upregulation following apigetrin treatment.