3 results match your criteria: "Veterans General Hospital-Kaohsiung and National Yang-Ming University School of Medicine[Affiliation]"

Endothelin-1 (ET-1), a 21 amino acid peptide originally purified from conditioned medium of cultures of porcine aortic endothelial cells, is recognized as a product of many other cells as well. It is now known that there are three endothelin genes in the human genome (ET-1, ET-2, and ET-3). ET-1 and ET-2 are both strong vasoconstrictors, whereas ET-3 is a potentially weaker vasoconstrictor than the other two isoforms.

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Article Synopsis
  • This study aimed to analyze prostatic tuberculosis by assessing its clinical features and the outcomes of antituberculous chemotherapy in 18 patients with a median age of 66.7 years, focusing on prostate-specific antigen (PSA) levels prior to treatment.
  • Eight patients underwent a triple-drug chemotherapy regimen for an average of 7.6 months, and follow-ups included biannual biopsies and PSA tests to monitor progress.
  • Results showed that all patients were symptom-free over a median follow-up period of 3.4 years, with no relapses detected and improved PSA levels in some cases, indicating effective treatment management of prostatic tuberculosis.
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Endothelin is a novel potent vasoconstrictor peptide produced by a wide variety of cell types and which has diverse biological activities. Previously we have reported that thyroid hormone status alters tissue levels of immunoreactive endothelin (irET) in rats. In order to study whether plasma irET levels in humans are affected by thyroid hormone status, we measured irET concentrations by means of radioimmunoassay in plasma samples from euthyroid controls as well as from patients with either hypothyroidism or hyperthyroidism.

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