3 results match your criteria: "Veterans Administration Greater Los Angeles Healthcare Center[Affiliation]"

Context: Longitudinal studies examining care for seriously ill patients are needed to understand patients' experience of illness, evaluate interventions, and improve quality of care. Unfortunately, such studies face substantial methodological challenges.

Objectives: This article describes such challenges and the strategies used to overcome them in a successfully implemented palliative care intervention trial for veterans.

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Article Synopsis
  • Severe hematochezia has become a common reason for hospitalization, with shifting causes due to an aging population and changes in how colonoscopies are performed.
  • A thorough history, physical and rectal exams, along with nasogastric lavage, are crucial during patient resuscitation to pinpoint the source of the bleeding.
  • Urgent colonoscopy following colon purging is a highly effective method for diagnosing and treating bleeding, providing better outcomes and cost benefits compared to traditional elective colonoscopy approaches.
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Purpose: To study the pharmacologic and synaptic basis for the early loss of paired-pulse inhibition that occurs in the perforant-path stimulation model of status epilepticus.

Methods: Hippocampal slices were prepared from male Wistar rats. Test paired pulses (20- to 50-ms interstimulus interval) of the perforant path were used before and after an abbreviated period of perforant-path stimulation (1-5 min; 2-Hz continuous with 20 Hz of 10 s/min pulses) while either recording field potentials from the dentate gyrus granule cell layer or directly measuring whole-cell patch-clamp currents from granule cells.

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