268 results match your criteria: "Verruciform Xanthoma"

Oral Verruciform Xanthoma of the Lower Lip: A Rare Entity.

Cureus

November 2024

Oral Pathology and Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.

Oral verruciform xanthoma (OVX) is a rare entity, and only a handful of cases have been reported in the literature to date. This innocent-looking lesion can mimic any benign epithelial or connective tissue origin neoplasm. It can present with variations in surface color and texture.

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Verruciform xanthomas are rare lesions affecting 0.025-0.5% of the population.

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[Not Available].

Swiss Dent J

June 2024

Klinik für Oral Health & Medicine, Universitäres Zentrum für Zahnmedizin Basel UZB, Uni-versität Basel, Schweiz.

Article Synopsis
  • * Its exact cause is unknown, and while it can occur in healthy people, it has also been seen in those with autoimmune conditions or chronic graft-versus-host disease (GvHD).
  • * The recommended treatment is to surgically remove the lesion, as demonstrated in a case involving a successful excision from a 56-year-old patient with GvHD after stem cell transplantation for Non-Hodgkin lymphoma.
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Article Synopsis
  • The text discusses a rare case of verruciform xanthoma of the penis in a male patient who also has genital lichen sclerosus.
  • This is only the second documented case of this particular condition.
  • The authors recommend that when diagnosing verruciform xanthoma, healthcare providers should closely check for signs of lichen sclerosus, as these signs can be subtle.
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Oral verruciform xanthomas mimicking potentially malignant disorders.

J Clin Exp Dent

April 2024

DDS, MSc, PhD. Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, Brazil.

Article Synopsis
  • Verruciform xanthoma is a rare reactive lesion that typically appears in the skin but can also occur in the oral cavity, where it may be mistaken for leukoplakia.
  • The text describes two cases of 30-year-old individuals with white plaques on the tongue and floor of the mouth, which were confirmed to be oral verruciform xanthomas through histopathological analysis.
  • It's important for dental professionals to consider verruciform xanthoma in their differential diagnosis for potential oral cancer since it can appear in high-risk areas, with histopathological analysis being the most reliable method for diagnosis.
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A Case of Verruciform Xanthoma of Labia in a Child.

Clin Cosmet Investig Dermatol

April 2024

Dermatology Hospital of Jiangxi Province, Nanchang, Jiangxi, People's Republic of China.

Article Synopsis
  • - The study presents a case of verruciform xanthoma (VX), a rare and benign skin condition, found in a 12-year-old female with vulvar lesions lasting over a decade without discomfort.
  • - Examination revealed red, lobulated patches and specific histopathological features, including abnormal keratinization and inflammatory cell infiltration, leading to the diagnosis of VX.
  • - Surgical treatment resulted in a successful outcome, highlighting an effective approach for managing this condition.
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Article Synopsis
  • Verruciform acanthotic vulvar intra-epithelial neoplasia (vaVIN) is a rare condition that does not associate with HPV and presents unique challenges in diagnosis, particularly when differentiating it from non-neoplastic lesions.
  • The study evaluated the diagnostic effectiveness of three immunohistochemical markers—CK17, SOX2, and GATA3—across 16 vaVIN cases and 34 similar, non-neoplastic conditions, revealing that these markers are significantly more prevalent in vaVIN cases.
  • Findings suggest that utilizing a combination of these markers can increase the sensitivity, specificity, and accuracy of vaVIN diagnosis, aiding pathologists in distinguishing it from benign hyperplastic lesions.
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Article Synopsis
  • - *Verruciform xanthoma (VX) is a rare, benign lesion found in the oral mucosa and occasionally in other regions, but differences in its characteristics outside the mouth are not well understood.* - *A study reviewed 110 VX cases over 22 years, finding a median patient age of 55, with common oral sites including the palate and buccal mucosa, while extraoral lesions were larger and included areas like the scrotum and vulva.* - *Microscopic examination revealed notable differences, with extraoral lesions showing more frequent keratin projections and inflammation compared to oral lesions, indicating the need for careful diagnosis and management based on lesion location.*
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[Verrucous exophytic tumor of the glans penis].

Dermatologie (Heidelb)

March 2023

Universitäts-Hautklinik Tübingen, Eberhard-Karls-Universität, Liebermeisterstr. 25, 72076, Tübingen, Deutschland.

A 59-year-old man presented with a growing tumor on the glans penis, which we excised. Histologically, there was an acanthotic epidermis under which the papillary dermis was filled with foamy macrophages, best seen in a CD 68 stain. Verruciform xanthoma was diagnosed.

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Article Synopsis
  • - Verruciform xanthoma is a rare, benign growth typically found in the mouth but can appear on other skin areas, often occurring alone but sometimes linked to other health conditions.
  • - COVID-19, caused by the SARS-CoV-2 virus, primarily affects the respiratory system, but its effects and associations with other health issues are still being studied.
  • - This text discusses two cases of Verruciform xanthoma in patients with confirmed COVID-19 infection and reviews existing literature to explore any potential connections between this benign growth and the viral infection.
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Article Synopsis
  • Verruciform xanthoma (VX) is a rare, non-cancerous skin growth that appears as a warty-looking lesion, most commonly found on the vulva, especially the labia minora and clitoris.* -
  • The lesions can be mistakenly diagnosed as other skin issues like warts or cancers, and factors like chronic inflammation, trauma, and scratching may contribute to their development.* -
  • Treatment typically involves surgically removing the lesions for complete resolution.*
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Cutaneous malakoplakia with verruciform xanthoma in the same lesion.

Clin Exp Dermatol

August 2022

Department of Dermatology, Dermatology Hospital, Southern Medical University, Guangzhou, China.

Article Synopsis
  • Cutaneous malakoplakia (CM) is a rare, chronic skin disease known for specific structures called Michaelis-Gutmann bodies (MGB) that can be seen under a microscope.
  • Verruciform xanthoma (VX) is another rare skin lesion that appears benign, featuring certain growth patterns and inflammation in the skin.
  • The text describes a case of an elderly Chinese man who has both CM and VX, with the diagnosis confirmed through histological examination showing MGB.
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Verruciform xanthoma associated with lichen planus.

Autops Case Rep

February 2022

Universidade Federal do Rio Grande do Norte, Stomatology and Oral Pathology, Natal, RN, Brasil.

Article Synopsis
  • Verruciform xanthoma (VX) is a rare, benign lesion often found in the mouth, characterized by its painless, rough appearance and varying colors, typically affecting the gingiva and alveolar mucosa.
  • A clinical case is reported involving VX in the buccal mucosa that was associated with oral lichen planus, which was confirmed through histopathological analysis showing inflammation and specific cell characteristics.
  • Immunohistochemical tests indicated the presence of lipid-laden macrophages (xanthoma cells) in the VX, and the patient is currently being monitored with no recurrence of the VX but has ongoing lesions from lichen planus.
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Article Synopsis
  • Carcinoma cuniculatum (CC) is a rare type of squamous cell carcinoma that typically invades locally and rarely spreads, characterized by an intricate growth pattern of squamous epithelium and keratin structures.
  • A case report discusses a 39-year-old man with painful swelling in the right maxillary gingiva, initially misdiagnosed as verruciform xanthoma after two negative biopsies, but later accurately identified as CC due to discrepancies between biopsy reports and clinical imaging.
  • The report emphasizes the challenges in diagnosing CC, showcasing the need to combine clinical signs and pathological results, and contributes to the literature by detailing this exceptional case of CC in the gingiva.
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Article Synopsis
  • Verruciform xanthoma is a rare, benign skin and mucosal lesion typically found in the oral cavity but can also occur in other areas, as illustrated by a case of a 39-year-old woman with vulvar and limb lesions.
  • The patient presented with cauliflower-like tumors in the vulva and yellow, verrucous growths on her extremities, leading to a diagnosis of both verruciform xanthoma and generalized verrucous nevus.
  • Treatment involved surgical removal of the vulvar and peripheral lesions, along with oral Acitretin for the extremity lesions; a follow-up after three months showed improvement in the skin condition.
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