460 results match your criteria: "Ventilation Graphics"

The flow-volume loop (FVL) is a valuable yet often underutilized tool for assessing the placement of the laryngeal mask airway (LMA) during surgery. It provides real-time graphical data on airway patency and ventilation. These cases examine the role of FVL in identifying LMA misplacement.

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Long Term Ventilation in Pediatric Central Apnea: Etiologies and Therapeutic Approach over a Decade.

Pediatr Pulmonol

November 2024

Pediatric Pulmonology and Respiratory Intermediate Care Unit, Sleep and Long-Term Ventilation Unit, Academic Department of Pediatrics, Pediatric Hospital "Bambino Gesù" Research Institute, Rome, Italy.

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Article Synopsis
  • A new lung ultrasound technique called Anatomical M-Mode Evaluation for Lung Swings (AMLES) is introduced for evaluating lung function.
  • This method measures the movement of the lung curtain at the costophrenic recesses to assess respiratory mechanics.
  • The technique converts lung movement into graphical data, improving lung ventilation assessment in emergency situations.
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  • Infections resistant to antibiotics, especially carbapenem-resistant ones, are a serious global health issue, particularly in cases of hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP).
  • The review explores sulbactam-durlobactam therapy (SUL-DUR), assessing its approval process, how it works, and its potential in treating these bacterial infections.
  • SUL-DUR, known as Xacduro, has shown safety and effectiveness in clinical trials, making it a promising treatment alternative compared to traditional options like colistin for VAP, HAP, and related infections.
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  • * The review will use the PICO framework to focus on adult patients’ experiences with mechanical ventilation, and will include a range of study designs, from qualitative to quantitative, utilizing various databases for comprehensive data collection.
  • * Findings from the SR will identify themes and gaps in existing literature, offering insights that could influence healthcare policies, improve practices, and guide future research in the field of patient care during mechanical ventilation in LLMICs.
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  • The study aimed to analyze how tracheostomy placement impacts the hemodynamic stability of patients recovering from cardiac surgery who need extended ventilation.
  • Researchers reviewed data from cardiac surgery patients who received tracheostomies between 2018 and 2022, excluding those with other serious complications or on mechanical support.
  • Results showed a significant decrease in the vasoactive-inotrope score and a reduction in patients needing vasoactive/inotropic and sedative infusions after tracheostomy, indicating improved hemodynamic stability and suggesting its potential benefits for recovery.
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  • The paper outlines a user-friendly indoor air quality (IAQ) monitoring system designed for homes lacking automatic ventilation.
  • It features low-cost air quality sensors and an intuitive interface that visually represents air quality levels, helping users understand when to ventilate their spaces.
  • The system includes real-time air quality forecasts and has been tested successfully, showing improved user experience and technical performance based on user feedback.
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Association of Premorbid GLP-1RA and SGLT-2i Prescription Alone and in Combination with COVID-19 Severity.

Diabetes Ther

May 2024

Division of Endocrinology and Metabolism, Department of Medicine, University of North Carolina School of Medicine, Campus Box #7172, 8072 Burnett Womack, 160 Dental Circle, Chapel Hill, NC, 27599, USA.

Article Synopsis
  • - Individuals with type 2 diabetes face an increased risk of severe COVID-19 outcomes, prompting a study of various diabetes medications' effects on COVID-19 severity.
  • - The study analyzed data from over 78,000 people to compare the impact of GLP-1 receptor agonists (GLP-1RA) and sodium-glucose cotransporter-2 inhibitors (SGLT-2i) on outcomes like 60-day mortality and hospital visits after a SARS-CoV-2 infection.
  • - Results indicated that both GLP-1RA and SGLT-2i were linked to reduced mortality rates compared to another medication class, with combined use of both drugs showing similar mortality benefits but potentially lower hospital visit rates
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Newborn resuscitation timelines: Accurately capturing treatment in the delivery room.

Resuscitation

April 2024

Faculty of Health Sciences, University of Stavanger, Stavanger, Norway; Department for Simulation-based Learning, Stavanger University Hospital, Stavanger, Norway. Electronic address:

Article Synopsis
  • The study evaluated the effectiveness of newborn resuscitation timelines to track the incidence and response to resuscitation methods after birth, focusing on newborns receiving positive pressure ventilation (PPV).
  • Conducted at Stavanger University Hospital, the study analyzed 289 infants, noting that PPV was typically started around 72 seconds after birth, with a significant fraction of the infants being apneic or breathing ineffectively.
  • The results indicate that the use of these timelines can provide valuable insights for improving resuscitation practices by presenting complex data in an easily understandable format.
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  • The methacholine challenge test (MCT) is a key method for assessing airway hyperresponsiveness, particularly for diagnosing and treating bronchial asthma.
  • A consensus group of experts in respiratory health has updated guidelines on MCT usage, focusing on common clinical issues, preparation, safety, and result interpretation.
  • The updated guidelines specify who should undergo the MCT, outline absolute contraindications, and aim to assist healthcare practitioners in effectively using the test for patient assessment and treatment decisions.
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  • High-frequency ventilation (HFV) is commonly used for critically ill preterm babies, and this study examined the occurrence of acute kidney injury (AKI) in neonates under 29 weeks gestation who received HFV compared to other ventilation methods.
  • The research was a retrospective cohort study involving data from 24 neonatal intensive care units, excluding several factors that could skew results, and categorized subjects based on their type of respiratory support.
  • Findings indicate that AKI incidence was highest in the CPAP/no ventilation group (48.5%), followed by HFV (42.6%), and lowest in conventional ventilation (28.4%), suggesting a significant association between HFV and the risk of AKI in these vulnerable infants.
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  • The study aimed to review and analyze how effectively lung ultrasound score (LUS) can predict extubation failure in neonates on mechanical ventilation.
  • It included data from eight observational studies with a total of 564 participants, finding a pooled sensitivity of 82% and specificity of 83% for LUS in this context.
  • The researchers concluded that while LUS shows promise as a predictive tool, more large-scale, standardized studies are necessary to validate its effectiveness and improve methodology.
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  • The flow-volume loop (FV-loop) visualizes airflow during mechanical ventilation, showing how well the lungs are working (compliance) and how easily air moves through the airways (resistance).
  • A case study of a five-month-old boy with respiratory failure revealed a fixed airway obstruction through specific patterns in the FV-loop graphics.
  • The patient was diagnosed with a left pulmonary artery sling and other tracheal issues, underwent surgery, and was successfully discharged after a 47-day hospital stay.
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Eculizumab use in patients with pneumococcal-associated hemolytic uremic syndrome and kidney outcomes.

Pediatr Nephrol

December 2023

Department of Pediatric Nephrology, 2nd Faculty of Medicine, University Hospital Motol, Charles University, Prague, Czech Republic.

Article Synopsis
  • Streptococcus pneumoniae-associated hemolytic uremic syndrome (P-HUS) is a rare and serious condition, with limited studies on the use of eculizumab for treatment.
  • In this study, data from 7 patients (4 females and 3 males) with pneumonia were analyzed, where 4 received eculizumab, resulting in shorter dialysis and mechanical ventilation times compared to those who did not receive the drug, although still longer than typical durations.
  • The use of eculizumab did not significantly improve kidney outcomes over existing reports, and the study found strong correlations between chronic kidney disease (CKD) and the length of dialysis and ventilation support needed.
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Long-term kidney follow-up after pediatric acute kidney support therapy for children less than 15 kg.

Pediatr Nephrol

November 2023

Faculty of Medicine, Department of Pediatrics, Division of Pediatric Nephrology, Hacettepe University, Sihhiye, Ankara, Türkiye.

Article Synopsis
  • The study analyzed clinical characteristics and long-term outcomes of children under 15 kg who underwent different types of acute kidney support therapy: hemodialysis (HD), peritoneal dialysis (PD), and continuous kidney replacement therapy (CKRT).
  • Out of 109 patients, 64% died shortly after treatment, with survival correlating with lower use of vasopressors and absence of mechanical ventilation.
  • Follow-up evaluations showed a significant percentage of survivors had kidney risk factors, demonstrating the importance of extended monitoring for patients following acute kidney treatment.
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The oxygen transport cascade and exercise: Lessons from comparative physiology.

Comp Biochem Physiol A Mol Integr Physiol

August 2023

Department of Anesthesia and Perioperative Medicine, Mayo Clinic, Rochester, USA; Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN, USA. Electronic address:

Article Synopsis
  • Animal physiology studies enhance our understanding of human physiology, exemplified by the 'Krogh Principle', which suggests that certain animal models are ideal for specific research problems.
  • The review examines three stages of the oxygen transport process, focusing first on how cold, dry air impacts the airways of elite athletes like skiers and sled dogs.
  • It also delves into oxygen transport via hemoglobin in humans and deer mice, and highlights how equine models help overcome challenges in measuring respiratory muscle blood flow in exercising humans.
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  • This study investigates how acute kidney injury (AKI) affects children and whether it leads to persistent kidney dysfunction called acute kidney disease (AKD), along with its risk of causing chronic kidney disease (CKD).
  • Researchers analyzed data from 528 hospitalized children with AKI between 2015 and 2019, finding that 56.3% developed AKD and that 45.5% of those with AKD later developed CKD, compared to only 18.7% without AKD.
  • Key risk factors for the transition from AKI to AKD included child age, admission to specific care units, prematurity, underlying health conditions, and severity of kidney injury, indicating
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Article Synopsis
  • - The study examined how changing from volume-controlled ventilation to pressure-controlled ventilation affects patients' respiratory distress and asynchrony during mechanical ventilation in an ICU setting.
  • - It included 70 patients, comparing asynchronous evaluation and measuring variables like tidal volume and arterial carbon dioxide levels before and after the switch in ventilation modes.
  • - Results showed that both groups experienced a significant reduction in asynchrony, indicating that switching to pressure-controlled ventilation improves patient comfort and adaptation to the ventilator.
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  • - This study investigates rodent drinking behavior to understand factors like thirst, circadian rhythms, and the impact of drugs, but traditional fluid intake methods are inefficient and lack detail.
  • - The researchers developed the LIQ HD (Lick Instance Quantifier Home cage Device), which uses capacitive sensors for accurate lick detection, enabling analysis of licking behavior in multiple cages with a user-friendly touchscreen interface.
  • - LIQ HD allows for minute-to-minute tracking of drinking behavior in up to 18 rodent cages, providing validated data on preferences and licking patterns over extended periods, and it's designed to be open-source for wider research application.
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Early postoperative weight-based fluid overload is associated with worse outcomes after neonatal cardiac surgery.

Pediatr Nephrol

September 2023

Department of Pediatrics, Division of Pediatric Cardiology, Heart Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.

Article Synopsis
  • The study assesses how a weight-based fluid balance (FB-W) greater than 10% on postoperative day 2 (POD2) affects outcomes in neonates after cardiac surgery.
  • It involves data from 22 hospitals, analyzing 997 neonates, and found that 45% had FB-W >10%, which correlated with increased illness severity and negative outcomes.
  • Although hospital mortality was not significantly linked to FB-W >10%, it was associated with longer durations of mechanical and respiratory support, as well as increased hospital stays.
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  • A retrospective study was conducted to analyze the occurrence of unrecognized acute kidney injury (CSA-AKI) in pediatric cardiac surgery patients, focusing on the effects of infrequent serum creatinine (SCr) tests.
  • Out of 557 patients, 313 (56.2%) were found to have CSA-AKI, with 188 (33.8%) cases being unrecognized due to limited SCr measurements.
  • The study concluded that unrecognized CSA-AKI significantly correlates with longer mechanical ventilation, elevated postoperative BNP levels, and an extended hospital stay, highlighting the need for more frequent monitoring.
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  • Mechanical ventilators (MVs) are vital medical devices used in surgeries and intensive care units to help critical patients breathe more easily by reducing their work of breathing.
  • This study focuses on piston-driven MVs, which can operate in several modes like volume control and pressure control, with pressure-controlled ventilation being especially beneficial during laparoscopic surgeries for improved oxygenation and lower stress responses.
  • The research proposes a new optimal internal model control-based proportional integral (IMC-PI) controller, optimized using an enhanced class topper optimization (ECTO) algorithm, to ensure the ventilator accurately matches the patient's pressure requirements and mitigates diaphragmatic dysfunction.
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