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The Association of ANRIL With Coronary Artery Disease And Aortic Aneurysms, How Far Does The Gene Desert Go?
Ann Vasc Surg
March 2022
Vascular & Endovascular Surgery, Velindre University Hospital NHS Trust, Health & Education Improvement Wales, Cardiff, UK. Electronic address:
Article Synopsis
- The review focuses on the gene ANRIL and its associations with coronary artery disease (CAD) and aortic aneurysms (AA), highlighting the need for better understanding of their genetic links.
- Various single nucleotide polymorphisms (SNPs) related to ANRIL are identified as significantly linked to CAD and AA, with some SNPs like rs1333049 showing different correlations with each disease.
- The study suggests that ANRIL could be useful for future patient screening and risk assessment, although more research is necessary to clarify its role in connecting these two cardiovascular conditions.