Genome Features and Activity against Influenza A and SARS-CoV-2 Viruses of Six Probiotic Strains.

Purpose: The aim of this work was to analyze the complete genome of probiotic bacteria 8 RA 3, 90 TC-4, 39, 791, 1, and 379 and to test their activity against influenza A and SARS-CoV-2 viruses.

Methods: To confirm the taxonomic affiliation of the bacterial strains, MALDI TOF mass spectrometry and biochemical test systems were used. Whole genome sequencing was performed on the Illumina Inc.

Humoral immunity to influenza in an at-risk population and severe influenza cases in Russia in 2016-2017.

This work aimed to analyze the herd immunity to influenza among a Russian population living in regions with an increased risk of emergence of viruses with pandemic potential, and to isolate and investigate virus strains from severe influenza cases, including fatal cases, during the 2016-2017 epidemic season. In November 2016 - March 2017 highly pathogenic influenza outbreaks were registered in Russia among wild birds and poultry. No cases of human infection were registered.