2,490 results match your criteria: "Vascular and Pediatric Surgery at Würzburg University Hospital[Affiliation]"

Background: Esophageal atresia is one of the most common life-threatening congenital malformations and is defined as an interruption in the continuity of the esophagus with or without fistula to the trachea or bronchi. Definitive treatment is surgical ligation of the fistula if present and esophageal end-to-end anastomosis of the two pouches, thereby reconstructing the continuity of the esophagus. During this procedure, the surgeon may choose to either ligate or preserve the azygos vein, a major draining vein for the esophagus and surrounding structures, but no definitive consensus on the matter exists.

View Article and Find Full Text PDF

Adult patients with congenital heart disease (ACHD) requiring heart transplantation (HT) usually show complex anatomies, posing surgical challenges. Consequently, we analyzed technical aspects and early and long-term outcomes of additional surgical repairs during HT in ACHD. Forty patients were identified (23 males, median age: 38 years, interquartile range [IQR]: 26-50).

View Article and Find Full Text PDF

Advances in the Treatment of Neonatal Coarctation of the Aorta.

Pediatrics

January 2025

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany.

Coarctation of the aorta (CoA) is a potentially life-threatening congenital and obstructive anomaly of the distal aortic arch. After constriction of the ductus arteriosus, neonates may develop critical CoA in the isthmus area and present with severe left ventricular dysfunction or even cardiac failure. Low cardiac output and abdominal hypoperfusion (distal to the coarctation) may lead to metabolic derangements and clinical deterioration.

View Article and Find Full Text PDF

Chronic postoperative inguinal pain (CPIP) after pediatric inguinal hernia repair-a retrospective analysis.

Hernia

January 2025

Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital of Wuerzburg, Wuerzburg, Germany.

Background: Surgical treatment of inguinal hernias in children is one of the most common operative procedures worldwide. During surgery for inguinal hernias in adults, chronic pain develops in approximately 10% of all cases. In children, there has been limited research to determine whether they may also develop this chronic postsurgical inguinal pain (CPIP).

View Article and Find Full Text PDF

The sarcoma ring trial: a case-based analysis of inter-center agreement across 21 German-speaking sarcoma centers.

J Cancer Res Clin Oncol

January 2025

Sarcoma Unit, Department of Surgery, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.

Purpose: The management of soft tissue sarcoma (STS) at reference centers with specialized multidisciplinary tumor boards (MTB) improves patient survival. The German Cancer Society (DKG) certifies sarcoma centers in German-speaking countries, promoting high standards of care. This study investigated the variability in treatment recommendations for localized STS across different German-speaking tertiary sarcoma centers.

View Article and Find Full Text PDF

Open abdomen treatment (OAT) is associated with significant morbidity and mortality. In cases where primary or delayed fascial closure cannot be achieved, vacuum-assisted wound closure and mesh-mediated fascial traction are indicated, which often result in a planned ventral hernia. If secondary skin closure is not feasible, common treatment of granulated abdominal defects involves split-thickness skin-grafting or healing by secondary intention leading to significant scarring and sometimes mutilating defects.

View Article and Find Full Text PDF

Preduodenal portal vein (PDPV) is a rare congenital vascular malformation, which was first described by Knight in 1921 as an anomalous vein that lies in front of the duodenum, common bile duct, and hepatic artery instead of beneath them. This abnormal position may result in congenital duodenal obstruction and puts it in danger during operations around this region. PDPV is typically associated with other congenital anomalies, mainly intraabdominal and cardiac ones.

View Article and Find Full Text PDF

We report our hospital-based experience in management strategies and outcomes for pediatric extremity vascular trauma at a major trauma center. A retrospective chart review was conducted on patients under 18 with extremity vascular injuries who had surgery between May 2021 and February 2023. Among 46 children, 16 (34.

View Article and Find Full Text PDF

Introduction: This study investigates risk factors and surgical outcomes in pediatric patients with congenital heart defects (CHD) who develop ischemic colitis (IC). Previous research indicates a higher IC risk in very low birth weight neonates with CHD.

Methods: A retrospective analysis compared an IC-CHD group to a CHD-only group.

View Article and Find Full Text PDF

Minimally Invasive Mitral Valve Repair with Intercostal Cryoablation: A Case Report.

Thorac Cardiovasc Surg Rep

January 2024

Department of Adult and Pediatric Cardiac and Vascular Surgery, University Hospital Giessen and Marburg Campus Giessen, Giessen, Hessen, Germany.

 Minimally invasive lateral thoracotomies may cause severe postoperative pain and discomfort. We describe an intraoperative intercostal cryo-neuronal pain block as one possibility for postoperative pain relief.  A 63-year-old male patient underwent minimally invasive mitral valve repair.

View Article and Find Full Text PDF

Arterio-ureteral fistula (AUF) is a rare condition affecting nearby adult-only patients. Patients usually present with hematuria, often starting as intermittent hematuria which frequently increases, and may lead to hemorrhagic shock. Without rapid diagnosis and prompt treatment, AUF can be lethal.

View Article and Find Full Text PDF

Bridging Distances and Enhancing Care: A Comprehensive Review of Telemedicine in Surgery.

Cureus

December 2024

Colorectal Surgery, Torbay and South Devon NHS Foundation Trust, Torbay, GBR.

Telemedicine in surgical care has undergone rapid advancements in recent years, leveraging technologies such as telerobotics, artificial intelligence (AI) diagnostics, and wearable devices to facilitate remote evaluation and monitoring of patients. These innovations have improved access to care, reduced costs, and enhanced patient satisfaction. However, significant challenges remain, including technical barriers, limited tactile feedback in telesurgery, and inequities arising from digital literacy and infrastructure gaps.

View Article and Find Full Text PDF

Aim: During the COVID-19 pandemic, social restrictions significantly impacted post-graduate training in pediatric surgery. This paper describes the implementation and continuation of a German-language, online training program for pediatric surgery residents, named "KiWI" (Kinderchirurgische Weiterbildung im Internet), which was established during the period of social distancing.

Method: "KiWI" was designed as a monthly, post-graduate online seminar course that combined practical relevance with theoretical knowledge.

View Article and Find Full Text PDF

Objective: Splenectomy is regularly performed in total and distal pancreatectomy due to technical reasons, lymph node dissection and radicality of the operation. However, the spleen serves as an important organ for competent immune function, and its removal is associated with an increased incidence of cancer and a worse outcome in some cancer entities (Haematologica 99:392-398, 2014; Dis Colon Rectum 51:213-217, 2008; Dis Esophagus 21:334-339, 2008). The impact of splenectomy in pancreatic cancer is not fully resolved (J Am Coll Surg 188:516-521, 1999; J Surg Oncol 119:784-793, 2019).

View Article and Find Full Text PDF

Fenestration has been reported to enhance Fontan hemodynamics in several cases of Fontan circulation. However, the indication criteria for fenestration remain under discussion. To assess the effectiveness of fenestration in Fontan circulation, we conducted a theoretical analysis using a computational model of the fenestrated Fontan circulation.

View Article and Find Full Text PDF

Among childhood cancer survivors, the cumulative incidence rate of differentiated thyroid carcinomas (DTCs) is estimated to be 8-11%. Although the association of DTC with prior radiotherapy is well-studied, the association with chemotherapy remains less understood. Most studies focused on young adults, leaving a knowledge gap on subsequent DTC occurring in childhood and adolescence.

View Article and Find Full Text PDF

Background: Covered stent correction for a sinus venosus atrial septal defect (SVASD) was first performed in 2009. This innovative approach was initially viewed as experimental and was reserved for highly selected patients with unusual anatomic variants. In 2016, increasing numbers of procedures began to be performed, and in several centers, it is now offered as a standard of care option alongside surgical repair.

View Article and Find Full Text PDF

The aim of this study was to evaluate the impact of coronary bypass surgery (CABG) on long-term mortality, comparing survival rates to those of the general population in Poland. The study was based on the Polish National Register of Cardiothoracic Surgical Procedures (KROK). Between January 2009 and December 2019, 133,973 patients underwent CABG.

View Article and Find Full Text PDF

Introduction: Abdominal surgery in children may disrupt normal gut function, necessitating prolonged fasting, which can lead to complications such as dehydration and nutritional deficits. Early enteral nutrition (EEN) after surgical procedures can enhance wound healing, prevent malnutrition, and expedite recovery. Although concerns exist regarding the risk of complications associated with EEN, current evidence suggests that it is not linked to increased perioperative complications.

View Article and Find Full Text PDF

Mesenteric sparing or extended resection in primary ileocolic resection for Crohn's disease.

Lancet Gastroenterol Hepatol

January 2025

Department for General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital of Wüerzburg, Würzburg 97080, Germany.

View Article and Find Full Text PDF

Sialidase NEU3 silencing inhibits angiogenesis of EA.hy926 cells by regulating Wnt/β-catenin signaling pathway.

Biochem Biophys Res Commun

January 2025

Office for West China Institute of Women and Children's Health, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, 610021, China. Electronic address:

Angiogenesis significantly drives tumor progression, and the functions of vascular endothelial cells are influenced by various factors. Tumor cells are characterized by abnormal sialylation, and their dynamic balance depends on sialyltransferases and sialidases. NEU3 is a plasma membrane-associated sialidase, vital for the regulation of cell surface sialylation.

View Article and Find Full Text PDF

Prospective Evaluation of Real-Time Artificial Intelligence for the Hill Classification of the Gastroesophageal Junction.

United European Gastroenterol J

December 2024

Interventional and Experimental Endoscopy (InExEn), Department of Internal Medicine 2, University Hospital Würzburg, Würzburg, Germany.

Background: Assessment of the gastroesophageal junction (GEJ) is an integral part of gastroscopy; however, the absence of standardized reporting hinders consistency of examination documentation. The Hill classification offers a standardized approach for evaluating the GEJ. This study aims to compare the accuracy of an artificial intelligence (AI) system with that of physicians in classifying the GEJ according to Hill in a prospective, blinded, superiority trial.

View Article and Find Full Text PDF

Osteogenesis imperfecta (OI) is a multisystem disorder most often caused by pathogenic variants in genes that encode type I collagen. Type I collagen is abundant not only in bone but also in multiple tissues including skin, tendons, cornea, blood vessels and heart. Thus, OI can be expected to affect cardiovascular system, and there are numerous reports of cardiovascular disease (CVD) in people with OI.

View Article and Find Full Text PDF

Background: Venous popliteal aneurysms are a rare but serious disease due to the risk of pulmonary embolism (PE). Aneurysms larger than 20 mm in diameter or with an embolic episode should be treated. The classic surgical technique is the tangential resection of the aneurysm with venorrhaphy, which may raise the risk of recurrence.

View Article and Find Full Text PDF