3,611 results match your criteria: "Valley Hospital[Affiliation]"

Article Synopsis
  • - The text discusses hemophagocytic lymphohistiocytosis (HLH), a severe condition often triggered by a cytokine storm, which can lead to death, particularly in the presence of sepsis that masks early HLH signs.
  • - A case study is presented where a patient showed persistent symptoms like high fever and confusion, ultimately being diagnosed with HLH after complications such as deep vein thrombus and renal failure despite treatments.
  • - Despite aggressive treatment for HLH, including antineoplastics and corticosteroids due to associated T-cell lymphoma, the patient’s condition deteriorated, leading to shock and eventually cardiac arrest.
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  • Around 50% of women referred for invasive coronary angiography experience angina but have nonobstructive coronary arteries, with conditions like vasospastic angina and microvascular dysfunction being key issues.
  • In a study from 2018 to 2023 involving 198 women, those who underwent coronary function testing (CFT) were more likely to be diagnosed with vasomotor disorders than those who only had coronary angiography (CA), with significant differences in the types of diagnoses given.
  • The results showed that after CFT, there was a higher rate of changes in medications and a more aggressive approach to antianginal therapy compared to just undergoing CA, highlighting the importance of coronary function
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  • - Oncocytic renal neoplasms pose significant diagnostic challenges, yet are generally nonaggressive, prompting discussion about the necessity of differentiating emerging subtypes like eosinophilic solid and cystic renal cell carcinoma and others.
  • - A survey of 63 urologic pathologists revealed that many encounter complex oncocytic tumors frequently, with 70% agreeing that eosinophilic solid and cystic renal cell carcinoma should be recognized as a distinct category, while opinions were more divided on other types.
  • - Diagnostic approaches varied among pathologists, with 60% hesitant to diagnose oncocytoma through needle biopsies, and a near split on the routine use of immunohistochemistry; common genetic testing was
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Effects of Antihypertensive Therapy During Pregnancy on Postpartum Blood Pressure Control.

Obstet Gynecol

October 2024

Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, University of Pennsylvania, Philadelphia, Pennsylvania, University of Texas at Houston, Houston, Texas, Columbia University, New York, New York, Duke University, Durham, North Carolina, St. Luke's University Health Network, Bethlehem, Pennsylvania, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, Metro Health/Case Western University, Cleveland, Ohio, Indiana University, Indianapolis, Indiana, Drexel University College of Medicine, Philadelphia, Pennsylvania, University of Utah Health, Salt Lake City, Utah, University of Texas Southwestern, Dallas, Texas, Intermountain Healthcare, Salt Lake City, Utah, Ochsner Health, New Orleans, Louisiana, University of Texas Medical Branch, Galveston, Texas, St. Peters University Hospital, New Brunswick, New Jersey, Washington University in St. Louis, St. Louis, Missouri, University of Mississippi Medical Center, Jackson, Mississippi, Magee Women's Hospital and University of Pittsburgh, Pittsburgh, Pennsylvania, The Ohio State University, Columbus, Ohio, Rutgers University-Robert Wood Johnson Medical School, Brunswick, New Jersey, Medical College of Wisconsin, Milwaukee, Wisconsin, University of South Alabama at Mobile, Mobile, Alabama, Weill Cornell University, New York City, New York, Yale University, New Haven, Connecticut, NYU Langone Hospital-Long Island, Mineola, New York, University of Colorado, Aurora, Colorado, Emory University, Atlanta, Georgia, Denver Health, Denver, Colorado, University of California, San Francisco, San Francisco, California, NewYork-Presbyterian Queens Hospital, Flushing, New York, Stanford University, Stanford, California, Arrowhead Regional Medical Center, Colton, California, Tulane University, New Orleans, Louisiana, Wright State University and Miami Valley Hospital, Dayton, Ohio, University of Kansas Medical Center, Kansas City, Kansas, Medical University of South Carolina, Charleston, South Carolina, Vanderbilt University School of Medicine, Nashville, Tennessee, and Tufts University School of Medicine, Boston, Massachusetts; Beaumont Hospital, Grand Rapids, Michigan; the Center for Women's Reproductive Health, the Department of Biostatistics, the Department of Pediatrics, and the Department of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama; the Christiana Care Center for Women's and Children Health Research, Newark, Delaware; Zuckerberg San Francisco General Hospital, San Francisco, California; the Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland; Virtua Health, Marlton, New Jersey; Oregon Health and Science University, Portland, Oregon; the Department of Obstetrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas; the Fetal Care Center of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; the Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Good Samaritan Hospital, Cincinnati, Ohio; the Department of Obstetrics, Gynecology and Women's Health, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Newark, New Jersey; Obstetrics and Gynecology/Maternal-Fetal Medicine, University of Tennessee Health Science Center, Memphis, Tennessee; the Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Lehigh Valley Health Network, Allentown, Pennsylvania; and Obstetrics and Gynecology and Women's Health Institute, Cleveland Clinic, Cleveland, Ohio.

Objective: To compare differences in postpartum blood pressure (BP) control (BP below 140/90 mm Hg) for participants with hypertension randomized to receive antihypertensive treatment compared with no treatment during pregnancy.

Methods: This study was a planned secondary analysis of a multicenter, open-label, randomized controlled trial (The CHAP [Chronic Hypertension and Pregnancy] trial). Pregnant participants with mild chronic hypertension (BP below 160/105 mm Hg) were randomized into two groups: active (antihypertensive treatment) or control (no treatment unless severe hypertension, BP 160/105 mm Hg or higher).

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Objectives: Enhanced recovery after surgery (ERAS) pathways are evidence-based practices that minimize perioperative physiologic stress, reducing postoperative complications and recovery time. This study assessed the Canadian application of, and adherence to, ERAS recommendations during minimally invasive gynaecologic surgery, and identified barriers to ERAS uptake.

Methods: A self-administered cross-sectional survey was distributed to obstetrics and gynaecology residents, fellows, and attendings through 3 national listservs from February 2021 to January 2022.

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Article Synopsis
  • Patella dislocation is a frequent knee injury that can lead to ongoing pain and a higher chance of future dislocations, with treatment options including surgery and physical therapy for stabilization and function restoration.
  • A clinical study compared outcomes for patients treated with medial patellofemoral ligament (MPFL) surgery versus conservative methods, assessing redislocation rates and knee function using the Kujala scale.
  • Results showed that surgical intervention led to significantly lower redislocation rates and improved knee function at a two-year follow-up, while differences in knee function between surgery types and conservative treatment were not significant at one year or two years after MPFL repair.
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Xanthogranulomatous Pyelonephritis (XGP) is a serious and rare inflammatory disease of unknown etiology. This systematic review analyzes XGP cases. We performed a literature search for "Pyelonephritis, Xanthogranulomatous.

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Calciphylaxis, also known as calcific uremic arteriolopathy, is a rapidly progressive, rare, and severe condition characterized by vascular calcification and skin necrosis. The pathophysiology involves cutaneous arteriolar calcification followed by subsequent tissue ischemia and infarction, which eventually causes extremely painful skin lesions. The condition is associated with substantial morbidity due to severe pain, non-healing wounds, increased susceptibility to infections, and frequent hospitalizations.

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  • Increased serotonin signaling is linked to structural changes in heart valves, particularly in the mitral valve, where reduced serotonin transporter (SERT) expression worsens degenerative mitral valve regurgitation.
  • Mice lacking SERT show significant heart issues, including fibrosis, reduced heart function, and abnormal heart sizes, with differences in gene expression patterns occurring at different ages between heart valves.
  • Valve interstitial cells from the mitral valve react more strongly to serotonin and TGFβ1 compared to other valves, suggesting that downregulation of SERT may make the heart more prone to pro-fibrotic changes, particularly in the mitral valve, which is also observed in human valve cells.
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Bipolar latissimus dorsi transfer has been considered a viable option for the restoration of elbow flexion in patients with large traumatic defects of the anterior arm compartment. Advantages of bipolar transfer of the latissimus include stabilization of the anterior shoulder joint in addition to recreating the biceps for a direct line of pull in restoring elbow flexion with minimal donor site morbidity. Previous literature in bipolar latissimus transfer has demonstrated good outcomes in elbow flexion against gravity, range of motion, and patient satisfaction.

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Article Synopsis
  • The NHL29 trial evaluated the effectiveness of combining ibrutinib with R-mini-CHOP chemotherapy in patients over 75 with newly diagnosed diffuse large B-cell lymphoma (DLBCL).
  • Results showed a 2-year overall survival rate of 68% and a progression-free survival rate of 60%, with an overall response rate of 76%.
  • Despite some serious adverse events, including infections and diarrhea, improvements in health-related quality of life were noted among responders, indicating the treatment's viability for elderly patients.
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Vaping-associated illness: a reassessment.

Int J Emerg Med

September 2024

Department of Emergency Medicine, Valley Hospital, 4 Valley Health Plaza, Paramus, NJ, 07652, USA.

Background: In 2019, there was widespread presentation of respiratory distress as well as other organ system involvement in patients with a history of vaping. There continue to be reports of vaping-associated illness (VAI). This has come to be known as e-cigarette and vaping product associated lung injury (EVALI).

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Article Synopsis
  • - Colorectal adenocarcinoma is the most common type of colorectal cancer in the U.S., driven by genetic mutations like APC, KRAS, HER-2 IHC3+, CHEK-2, and TP53 that result in cancer development.
  • - Standard treatment for metastatic colorectal cancer often includes chemotherapy and targeted therapies, but many patients endure disease progression, prompting the search for new treatments like fruquintinib, a selective VEGFR inhibitor.
  • - A case report describes a patient with metastatic colorectal cancer who suffered a cerebellar hemorrhage after starting fruquintinib, emphasizing the importance of close monitoring and personalized risk assessments for patients on this medication.
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Calyceal rupture, defined as the extravasation of urine from the renal calyces into the perinephric or paranephric spaces, typically results from increased intrapelvic pressure due to urinary tract obstruction. This condition can lead to the formation of a perinephric urinoma and severe complications, such as infection, abscess formation, and impaired renal function. Timely diagnosis and management are crucial to prevent these adverse outcomes.

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Pneumatosis intestinalis (PI) and hepatic portal venous gas (HPVG) are rare but potentially life-threatening conditions characterized by the presence of gas within the bowel wall and portal venous system, respectively. This case report presents a 45-year-old male with a history of methamphetamine use who developed severe metabolic and hemodynamic instability, marked by altered mental status, metabolic acidosis, and ST elevations. Despite aggressive resuscitation and intensive care, the patient unfortunately succumbed to his condition, highlighting the gravity of these complications.

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Article Synopsis
  • * The axillofemoral bypass graft is a key surgical option for treating complicated cases of peripheral artery disease, though it can lead to unexpected complications.
  • * A case of a 64-year-old man illustrates how trauma after surgery can cause a pseudoaneurysm that mimics stroke symptoms, highlighting the need for various diagnostic approaches in post-operative care.
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Cameron lesions are rare causes of upper gastrointestinal bleeding (UGIB). The lesions are linear erosions or ulcers that develop in the sac of a hiatal hernia, which often go unnoticed in the upper gastrointestinal system, and are a prevalent cause of anemia resulting from iron deficiency. Postponed treatment can result in severe consequences such as potentially fatal hemorrhaging.

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Article Synopsis
  • - The rise of cardiovascular diseases (CVDs) in low- and middle-income countries (LMICs) has become a significant public health issue, previously overshadowed by infectious diseases, yet many of these countries lack the resources needed for effective management.
  • - A systematic review conducted in 2023 evaluated barriers to primary CVD prevention in LMICs by analyzing 1089 papers, ultimately narrowing down to 18 relevant studies that highlighted obstacles within healthcare systems.
  • - The analysis revealed three main categories of barriers: physician (lack of guidelines and overwhelmed providers), patient (poor health literacy and lack of motivation), and health system (insufficient infrastructure and focus on secondary prevention), hindering effective primary prevention strategies.
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Background And Objectives: Care plans summarize a child with medical complexity's (CMC) medical history and ongoing care needs. Often, the health care team controls the care plan content, limiting caregivers' ability to edit the document in real time and potentially compromising accuracy and utility. With this study, we aimed to provide caregivers of CMC with online access and shared editing control of their child's care plan and to explore the experiences of caregivers and care team members (CTMs) after using an online collaborative care plan (OCCP).

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Background: As e-scooters have become common modes of transportations in urban environments, riding e-scooters has become a common mechanism of injury. This study examines the relationship between when riders are using these devices (i.e.

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Patients with a high-risk pregnancy or who immediately give birth are often not provided access to acute care occupational and physical therapy during their hospital admission. The greatest potential for health care crises, including maternal mortality, occurs during the first 6 weeks after birth. Maternal mortality and morbidity, which continue to rise in the United States, are considered indicators of the overall population health of a country.

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Zeroing in on Xylazine.

Prim Care Companion CNS Disord

August 2024

Hartford Behavioral Health, Hartford, Connecticut.

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Article Synopsis
  • The term atypical hemolytic uremic syndrome (aHUS) originated in the 1970s to differentiate between familial/sporadic cases and typical epidemic cases associated with Shiga toxin.
  • Over time, aHUS has become a broad term for various diseases that don't relate to Shiga toxin, complicating the definition and treatment strategies due to its diverse causes.
  • A group of experts used a consensus-building method called the Delphi approach to discuss and clarify the terminology and issues surrounding aHUS in light of advancements in medical science and targeted therapies.
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