Gastric juice and analysis of basal and stimulated secretion following treatment with rice-bran oil.

In determining whether rice-bran oil (RBO) has antisecretory activity, we induced stress ulcers in 20 Wistar rats (10 controls; 10 animals given 0.2 ml/day RBO orally for 4 days prior to ulcer induction). In turn, we analyzed gastric juice for histamine, pepsin, H+ concentration ([H+]) and output volume.

Factors of prognostic value in long-term survival of colorectal cancer patients.

We have studied 191 protocolized colorectal cancer patients, analyzing the prognostic factors described in the literature as being important to long-term survival. Of the data studied, sex, age, duration of symptoms, tumor location, tumor extension within the circumference of the bowel lumen, and the surgical technique employed, all showed differences in terms of five-year survival, but without reaching statistical significance. The factors with statistically significant prognostic value were first symptoms, occlusion, perforation, primary tumor size and configuration, lymph node involvement, degree of wall infiltration, presence of emboli, degree of differentiation and Scarff index.