3 results match your criteria: "Vaccine Development and Evaluation Centre (VDEC)[Affiliation]"
Vaccine
December 2024
Vaccine Development and Evaluation Centre (VDEC), UK Health Security Agency (UKHSA), Manor Farm Road, Porton, Salisbury SP4 0JG, United Kingdom. Electronic address:
Lancet Infect Dis
November 2024
Emerging Pathogen Serology group, Vaccine Development and Evaluation Centre (VDEC), UK Health Security Agency, Porton Down SP4 0JG, UK. Electronic address:
Virulence
December 2024
Vaccine Development and Evaluation Centre (VDEC), United Kingdom Health Security Agency, Salisbury, UK.
African swine fever (ASF) is a devastating disease with a high impact on the pork industry worldwide. ASF virus (ASFV) is a very complex pathogen, the sole member of the family , which induces a state of immune suppression in the host through infection of myeloid cells and apoptosis of lymphocytes. Moreover, haemorrhages are the other main pathogenic effect of ASFV infection in pigs, related to the infection of endothelial cells, as well as the activation and structural changes of this cell population by proinflammatory cytokine upregulation within bystander monocytes and macrophages.
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