2 results match your criteria: "VU Medical Centre and GGZ inGeest[Affiliation]"

Social dysfunction is transdiagnostically associated with default mode network dysconnectivity in schizophrenia and Alzheimer's disease.

World J Biol Psychiatry

November 2022

Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, Amsterdam UMC, VU Medical Centre and GGZ inGeest, Amsterdam, The Netherlands.

Article Synopsis
  • The study investigates the link between social dysfunction and the Default Mode Network (DMN), which is important in neuropsychiatric disorders, focusing on patients with schizophrenia and Alzheimer’s alongside healthy controls.
  • Using fMRI data, the research found that measures of social dysfunction (via specific scales) were associated with reduced DMN connectivity, particularly in certain brain regions.
  • The results suggest that changes in DMN connectivity could serve as potential biomarkers for social dysfunction across various mental health disorders, which may help in developing personalized treatment strategies.
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Background: This paper assesses the impact of a counselling intervention on reducing leprosy-related stigma in Cirebon District, Indonesia. The unique features of this intervention are its rights-based approach, the underlying Cognitive Behavioural Therapy (CBT) model, the three types of counselling and the lay and peer counsellors who were involved.

Methodology/principal Findings: Mixed methods (e.

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