2 results match your criteria: "VNUHCM-University of Science (HCMUS)[Affiliation]"

Nine compounds including a new one, garcichaudiic acid (), were isolated from the bark of and their structures were characterized mainly by 1 D and 2 D NMR experiments. The antioxidant capacity of the isolated compounds was determined using DPPH radical scavenging assay and the anti-hyperglycemic activity was assessed by measuring the inhibitory effect against α-glucosidase. Among them, compound showed higher antioxidant activity than the positive control, ascorbic acid, while both compounds and exhibited more significant α-glucosidase inhibitory activity than the reference drug acarbose.

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Triterpenoids from the bark of .

Nat Prod Res

January 2023

Natural Product and Medicinal Chemistry Lab, Faculty of Chemistry, VNUHCM-University of Science (HCMUS), Ho Chi Minh City, Vietnam.

Two new triterpenoids, entanolide () and methyl 3,4-secotirucalla-23-oxo-4(28),7,24-trien-21-al-3-oate (), together with nine known compounds (), were isolated from the bark of . Their structures were elucidated based on spectroscopic analyses, mainly 1 D and 2 D NMR spectral data. Compounds - and were evaluated for their cytotoxicity against HepG2 cells, and compounds exhibited weak activities.

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