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VIT University[Affiliation] Publications | LitMetric

1,782 results match your criteria: "VIT University[Affiliation]"

Mitigating Health Risks Through Environmental Tracking of Pseudomonas aeruginosa.

Curr Microbiol

December 2024

School of Bio Science and Technology, VIT University, Vellore, Tamil Nadu, 632014, India.

Pseudomonas aeruginosa is a prevalent nosocomial pathogen and a significant reservoir of antimicrobial resistance genes in residential and built environments. It is also widespread in various indoor and outdoor settings, including sewage, surface waters, soil, recreational waters (both treated and untreated), and industrial effluents. Surveillance efforts for P.

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The construction industry in Ghana is of paramount importance to the socio-economic progress of the country but recurringly faces noteworthy risk factors. The identification of crucial elements within the construction-risk category has not received considerable attention in the Ghanaian construction sector. This research work seeks to identify and classify the most critical construction-risk factors that impact construction projects in Ghana and also attempts to create a confirmatory factor model that could assist in understanding the potential of these factors.

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Liver cancer, with its robust metastatic propensity, imposes a substantial global health burden of around 800 000 new cases annually. Mutations in the Wnt/β-catenin pathway genes are common in liver cancer, driving over 80% of cases. Targeting this pathway could potentially lead to better treatments.

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Toxicity assessment of Oreochromis mossambicus exposed to carbamazepine and selenium: Physiological and genotoxic approach.

Environ Sci Pollut Res Int

December 2024

Nano Biosciences and Nanopharmacology Division, Biomaterials and Biotechnology in Animal Health Lab, Department of Animal Health and Management, Alagappa University, Science Campus 6th Floor, Karaikudi, Tamil Nadu, 630004, India.

Although the toxicity of selenium (Se) and carbamazepine (CBZ) has already been demonstrated, the possible effects of freshwater fish co-exposure to these pollutants have not been explored. Thus, we aimed to evaluate the potential impact of Se and CBZ (alone and combined) exposure (both 5 µg/L) in Oreochromis mossambicus after 28 days. Exposure to CBZ, alone or combined with Se, significantly increases the "red blood cells" and "mean corpuscular volume.

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The existence of a mutual relationship between gut microbiota and immune homeostasis highlights its importance in the context of kidney transplantation. The translational utility of gut microbiota as a biomarker for allograft injury has not been assessed before. In this study, we aimed to characterize the gut microbial diversity in kidney transplant recipients and investigate the alterations in the gut microbial composition in association with allograft injury such as histopathological graft rejection and calcineurin inhibitor toxicity.

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In this study, the characteristics of diesel engines were tested with in-house produced mahua biodiesel blended with diesel and copper oxide nanoparticles (CuO NP) catalyst. The preliminary investigation used mahua biodiesel-diesel blends (M10, M20, and M30) among them M20 outperformed. Further M20 and CuO NP with concentrations of 25, 50, and 75 ppm are studied.

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Comprehensive review of literature on Parkinson's disease diagnosis.

Comput Biol Chem

December 2024

VIT University, Vellore, Tamil Nadu 632002, India. Electronic address:

PD is one of the neurodegenerative illnesses affects 1-2 individuals per 1000 people over the age of 60 and has a 1 % prevalence rate. It affects both the non-motor and motor aspects of movement, including initiation, execution, and planning. Prior to behavioral and cognitive abnormalities like dementia, movement-related symptoms including stiffness, tremor, and initiation issues may be observed.

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A novel series of unsymmetrical bis-quinolin-3-yl chalcones has been synthesized under visible light using a Claisen-Schmidt condensation reaction between the 2-(morpholine-piperidine-pyrrolidine-thiomorpholine) substituted quinoline-3-carbaldehyde and 1-(2-methyl-4-phenylquinolin-3-yl) ethan-1-one derivatives, conducted at room temperature in the presence of NaOH/EtOH. The structures of the synthesized compounds have been confirmed by NMR spectroscopy and high-resolution mass spectroscopy. The synthesized compounds exhibit values ranging from 215 nm to 290 nm in non-polar to polar solvents, demonstrating positive solvatochromism.

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Exploring the Potential Long-term Impact of SARS-CoV-2 on Protein Misfolding and Amyloid-related Conditions.

Protein Pept Lett

November 2024

Vellore Institute of Technology, Centre for Bio Separation Technology (CBST), Technology Tower, VIT University, Vellore, Tamil Nadu 632014, India.

The long-term impact of the COVID-19 pandemic concerns risk to human health, particularly its potential association with protein misfolding and amyloidosis. This review article explores the causality relationship between SARS-CoV-2 infection, and protein misfolding, leading to amyloid-related conditions. It delves into the mechanisms by which viral proteins may accelerate amyloid formation, exacerbating post-infection complications, including neurological sequelae.

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Knowledge and attitude of adolescents towards sexual health and reproductive health technologies.

Afr J Reprod Health

August 2024

Sociology, School of Social Sciences and Languages, VIT University, Chennai Campus, India.

Reproductive health and reproductive health technologies are one of the challenging health studies in the developing world. The study focuses on the knowledge and attitude of adolescent students towards reproductive health technologies. It is the need and responsibility of all individuals especially adolescents (the future procreators) to know about Assisted Reproductive Technologies (ART) and the sexual health related to it.

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The measurement of Hemoglobin (Hb) by the non-invasive method is gaining popularity. The system, consisting of a photodiode is placed in between a Red (630 nm) and an IR (940 nm) LED, along with the signal conditioning circuits. 10 healthy male (8) and female (2) volunteers in the age group between 21 and 24 were recruited for this study.

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Harnessing the power of Arctium lappa root: a review of its pharmacological properties and therapeutic applications.

Nat Prod Bioprospect

August 2024

Department of Biotechnology, School of Biosciences and Technology, VIT University, SBST, VIT, Vellore, 632014, Tamil Nadu, India.

Arctium lappa, widely recognized as burdock, is a perennial plant that is employed in the realm of traditional Chinese medicine for a wide range of medicinal applications. The herb is rich in bioactive metabolites with therapeutic potential, encompassing polyphenolic antioxidants in its leaves, and flavonoids and fructo-oligosaccharides in its underground parts. Nutraceuticals originating from botanical sources such as Arctium lappa provide supplementary health advantages alongside their nutritional content and have demonstrated effectiveness in the prevention and management of specific ailments.

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Sustainable heavy metal (Cr(VI) ion) remediation: Ternary blend approach with chitosan, carboxymethyl cellulose, and bioactive glass.

Int J Biol Macromol

October 2024

PG and Research Department of Chemistry, D.K.M. College for Women (Autonomous), Affiliated to Thiruvalluvar University, Vellore, Tamil Nadu, India. Electronic address:

Heavy metal pollution poses a significant environmental challenge to worldwide, especially in developing countries. This study focuses on eliminating the heavy metal chromium (VI) ion from wastewater, employing an eco-friendly and economical ternary blend composed of Chitosan (CS), Carboxymethyl cellulose (CMC), and bioactive glass (BAG). The innovative bioactive glass is crafted from biosilica extracted from biowaste of cow dung ash, calcium oxide from eggshell ash, and phosphorus pentoxide.

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Bioactive chitosan films: Integrating antibacterial, antioxidant, and antifungal properties in food packaging.

Int J Biol Macromol

October 2024

Department of Biotechnology, School of BioSciences and Technology, VIT University: Vellore Institute of Technology, Vellore, Tamil Nadu, India, 632014. Electronic address:

In this work, chitosan was combined with bio-vanillin (BV) and kaolin clay (KC) to create a novel antifungal and biodegradable food packaging film. The chitosan/KC/BV film exhibited an antioxidant capacity of 80 % as measured by DPPH assay, which was significantly higher than that of the chitosan film which has 55.6 %).

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Wireless sensor networks' most prominent concern is energy optimization. It faces significant problems like high energy consumption, data loss, delay, and low network lifetime. To improve, it uses clustering.

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The expansion of 3,5-bis(arylidene)-4-piperidone derivatives with heterocyclic compounds such as 1,3-thiazole should take into account this correlation. The synthesized aminothiazolylacetamido-substituted 3,5-bis(arylidene)-4-piperidone derivatives - were found to have GI values in the range of 0.15-0.

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Optical imaging for diabetic retinopathy diagnosis and detection using ensemble models.

Photodiagnosis Photodyn Ther

August 2024

School of Computer Science and Engineering, VIT University, Chennai, Tamil Nadu, India. Electronic address:

Diabetes, characterized by heightened blood sugar levels, can lead to a condition called Diabetic Retinopathy (DR), which adversely impacts the eyes due to elevated blood sugar affecting the retinal blood vessels. The most common cause of blindness in diabetics is thought to be Diabetic Retinopathy (DR), particularly in working-age individuals living in poor nations. People with type 1 or type 2 diabetes may develop this illness, and the risk rises with the length of diabetes and inadequate blood sugar management.

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Objective: The goal of this study is to determine the accuracy of the PTW Beamscan program in determining the inflection point from Flattening Filter Free Beam Profile utilizing Multiple Detectors.

Methods: True Beam Linear Accelerator with 6FFF and 10FFF Photon Energies and 10 cm, 15 cm and 20 cm Field Sizes were used for this study. Profile measurements were taken with PTW's 729, 1,500, and 1,600 and the Starcheck system, the Pinpoint 3D with Beamscan system, and Linac's EPID.

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Purpose: The goal of this study is to investigate the dosimetric properties of a Semiflex three-dimensional (3D) chamber in an unflatten beam and compare its data from a small to a large field flattening filter-free (FFF) beam with different radiation detectors.

Methods: The sensitivity, linearity, reproducibility, dose rate dependency, and energy dependence of a Semiflex 3D detector in flattening filter and filter-free beam were fully investigated. The minimum radiation observed field widths for all detectors were calculated using lateral electronic charged particle equilibrium to investigate dosimetric characteristics such as percentage depth doses (PDDs), profiles, and output factors (OPFs) for Semiflex 3D detector under 6FFF Beam.

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Recent Advancements in Biosensors for the Detection and Characterization of Amyloids: A Review.

Protein J

August 2024

Centre for Bio Separation Technology (CBST), Technology Tower, Vellore Institute of Technology, VIT University, Vellore, 632014, Tamil Nadu, India.

Modern medicine has increased the human lifespan. However, with an increase in average lifespan risk of amyloidosis increases. Amyloidosis is a condition characterized by protein misfolding and aggregation.

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Pharmacokinetic studies, molecular docking, and molecular dynamics simulations of phytochemicals from Morus alba: a multi receptor approach for potential therapeutic agents in colorectal cancer.

Med Oncol

May 2024

Marine Biotechnology Laboratory, Department of Biomedical Sciences, School of Bio Sciences and Technology, VIT University, Vellore, Tamil Nadu, 632014, India.

Article Synopsis
  • The study investigates the potential of phytochemicals from Morus alba as treatments for colorectal cancer (CRC), a serious global health issue.
  • Using advanced techniques like molecular docking and dynamics simulations, the research analyzes how these phytochemicals interact with key proteins involved in CRC progression.
  • Out of 78 phytochemicals screened, 14 show promise as drug candidates, with Kuwanon A demonstrating the strongest interactions, suggesting it could serve as a viable alternative to existing CRC treatments like Capivasertib.
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The present study examines the factors that influence the adoption of environmentally friendly products and environmentally conscious consumption by individuals. The conceptual framework incorporates environmental knowledge, perceived behavioral control, environmental concern, and perceived consumer efficacy in order to highlight the factors that contribute to environmental consciousness. Incorporating the theories of reasoned action and planned behavior, 479 participants completed structured questionnaires as part of this study.

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A methodological approach based on rare earth elements analysis was developed to observe human activities in the stratigraphic sequence of Alagankulam. The site was one of the main ancient ports in south-eastern India and one of the transoceanic connecting points between East and West during the Classical Period. The sampled sediments where collected from vertical profiles, areas with traces of firing activities and filled deposits.

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Mosquito-borne disease pandemics, such as the Zika virus and chikungunya, have escalated cognizance of how critical it is to implement proficient mosquito vector control measures. The prevention of Culicidae is becoming more difficult these days because of the expeditious imminence of synthetic pesticide resistance and the universal expansion of tremendously invasive mosquito vectors. The present study highlights the insecticidal and larvicidal efficacy of the prospective novel actinobacterium derived from the marine Streptomyces sp.

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Andrographis echioides has been extensively utilized in traditional Indian folk medicines for several skin disorders and other biological actions such as diuretic, antimicrobial, anthelmintic, anti-ulcer, and hepatoprotective properties. Different crude extracts were extracted from A. echioides leaves using various solvents such as methanol and water.

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