5 results match your criteria: "VIP Animal Medical Center KR[Affiliation]"
Effect of Oligo-Fucoidan, Fucoxanthin, and L-Carnitine on Chronic Kidney Disease in Dogs: A Retrospective Study.
Animals (Basel)
June 2024
Laboratory of Veterinary Internal Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea.
Chronic kidney disease (CKD) commonly occurs in old dogs and cats. Oligo-fucoidan, fucoxanthin, and L-carnitine (OFL) compounds have a variety of reno-protective properties, including anti-inflammatory, anti-oxidative, and anti-fibrotic effects. Because their effects have not been investigated in naturally occurring canine CKD, we examined their reno-protective activities in dog patients with CKD.
View Article and Find Full Text PDFPeritoneal carcinomatosis with desmoplasia and osseous metaplasia mimicking encapsulating peritoneal sclerosis in a cat: case report.
Front Vet Sci
December 2023
Laboratory of Internal Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
Article Synopsis
- A 13-year-old neutered male cat showed symptoms of anorexia, lethargy, and a distended abdomen, which led to the discovery of ascites through abdominocentesis.
- Diagnostic tests including blood tests, imaging, and histopathology revealed signs of encapsulating peritoneal sclerosis (EPS) and identified the presence of fibrous membranes and calcifications in the abdomen.
- The final diagnosis was poorly differentiated invasive malignant neoplasms, categorized as carcinomatosis, marking it as the first reported case of sclerosing peritoneal carcinomatosis with osseous metaplasia in a cat.
Retrospective evaluation of prognosis and survival with various immunosuppressants in 82 dogs diagnosed with meningoencephalitis of unknown etiology (2010-2021).
BMC Vet Res
December 2023
Laboratory of Veterinary Internal Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine, Seoul National University, Seoul, 00826, Republic of Korea.
Article Synopsis
- Meningoencephalomyelitis of unknown etiology (MUE) is a non-infectious inflammatory brain condition in dogs, linked to abnormal autoimmune responses, and this study reviews the effects of different immunosuppressants on survival and clinical outcomes.
- A total of 82 dogs were assessed, revealing varying median survival times based on the treatment: leflunomide had the longest (1035 days), while a combination therapy showed the shortest (132 days), with no significant difference in adverse event rates except for moderate to severe anemia in one group.
- The findings suggest that the type of immunosuppressant impacts survival and response, particularly highlighting leflunomide as effective, but the study calls for
Palmar-plantar erythrodysesthesia syndrome resulting from toceranib phosphate in a dog with apocrine gland anal sac adenocarcinoma: a case report.
J Vet Sci
November 2023
VIP Animal Medical Center KR, City Place Bld., Seoul 02830, Korea.
An 11-year-old neutered male Miniature Poodle with a stage 3 apocrine gland adenocarcinoma was started on chemotherapy with toceranib phosphate after surgery. Beginning on day 10 of toceranib, the dog's foot pads became erythematous and hyperkeratinized. The dog complained of pain, inability to walk, depression, and loss of appetite.
View Article and Find Full Text PDFPotent Analgesic Action of 2-acetoxy-5-(2-4 (trifluoromethyl)-phenethylamino)-benzoic Acid (Flusalazine) in Experimental Mice.
J Pain Res
December 2022
GNT Pharma, Yongin, Gyeonggi, 17096, Republic of Korea.
Purpose: Nonsteroidal anti-inflammatory drugs (NSAIDs) and cyclooxygenase (COX)-2 selective inhibitors are the most widely used drugs to treat pain. Conventional NSAIDs and COX-2 selective inhibitors, however, cause several side effects such as gastric damage, kidney damage, and cardiovascular problems. Our previous study showed that 2-acetoxy-5-(2-4-(trifluoromethyl)-phenethylamino)-benzoic acid ie, flusalazine (also known as ND-07), which exerts dual actions by serving both as an anti-inflammatory agent and a free radical scavenger, is an effective and safe treatment for severe inflammatory diseases in mice.
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