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Eur J Pharmacol
December 2002
Division of Gastroenterology and Hepatology, VA Maryland Health Care System and the University of Maryland Medical System, 22 S. Greene Street, Room N3W62, Baltimore, MD 21201-1595, USA.
Bile acids alter regulatory pathways in several cell types. The molecular basis for these actions is not fully elucidated, but lithocholyltaurine interacts functionally with muscarinic receptors on gastric chief cells. In the present report, we demonstrate selective interaction of bile acids with Chinese hamster ovary (CHO) cells expressing each of the five muscarinic receptors.
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