Enhancement of the microwave photon-magnon coupling strength for a planar fabricated resonator.

Planar resonators have a wide usage in modern microwave technologies and perspectives in novel quantum technologies development. As was demonstrated earlier, their utilization allows to achieve high values of microwave photon-magnon coupling strength-an important parameter in technologies of information coherent transfer from electromagnetic GHz range to the optical range. In the present work, the achievement of the high value of the microwave photon-magnon coupling strength by exploiting the increase of the spatial concentration of the magnetic component of the planar resonator electromagnetic field is reported.

Vitamin A Reduces the Mortality of Animals with Induced Liver Fibrosis by Providing a Multi-level Body Defense System.

Background: Liver diseases remain the most important medical and biological problem. Works devoted to the study of the vitamin A role have shown conflicting results of its effect on the fibrosis development. We tested the hypothesis that an increase of the copper content in the liver, an example of which is Wilson's disease, shifts the balance in the redox system towards pro-oxidants, which leads to the antioxidant systems inhibition, including a decrease in the vitamin A content; this affects the levels of liver function regulation and the development of fibrosis.

High-Fat Diet as a Risk Factor for Breast Cancer: A Meta-Analysis.

High-fat diets have been identified as a major cause of obesity and a potential risk factor for breast cancer. Fat tissue, also known as adipose tissue, produces an excess of estrogen, which has been linked to an increased risk of breast cancer. Determining the impact of HFDs in the development and progression of breast cancer is essential, as it will enable us to identify the role of dietary modification in preventing and managing the disease.

Synthesis of Nanoparticles and Theoretical Model of Their Retention in Plasma of RF Capacitive Discharge with Vertically Arranged Electrodes in Acetylene.

In the present research, experiments on the formation and retention of nanoparticles (NPs) in the plasma of radio frequency (RF) capacitive discharge in acetylene were carried out with vertically positioned internal electrodes. It has been shown via SEM and TEM techniques that NPs found on the horizontal tube wall after the discharge operation have a spherical shape with a predominant diameter of approximately 400-600 nm. HRTEM analysis reveals their amorphous structure.

Current and Perspective Approaches to the Treatment of Prolactinomas.

Background: Along with the presence of the 2011 and numerous large-scale studies on the treatment of hyperprolactinemia of different origin, there are some unresolved questions, ambiguous and sometimes contradictory points of view regarding the management of patients with prolactinomas. This overview is devoted to the analysis of the results of modern clinical studies and the approaches towards the management of hyperprolactinemia caused by prolactinoma.

Materials And Methods: A systematic research of the literature for the appropriate keywords published mainly for the last 10 years was done; also, a reference list of each selected article was analysed.

SUCCOR quality: validation of ESGO quality indicators for surgical treatment of cervical cancer.

Objective: To evaluate whether compliance with European Society of Gynaecological Oncology (ESGO) surgery quality indicators impacts disease-free survival in patients undergoing radical hysterectomy for cervical cancer.

Methods: In this retrospective cohort study, 15 ESGO quality indicators were assessed in the SUCCOR database (patients who underwent radical hysterectomy for International Federation of Gynecology and Obstetrics (FIGO) stage 2009 IB1, FIGO 2018 IB1, and IB2 cervical cancer between January 2013 and December 2014), and the final score ranged between 0 and 16 points. Centers with more than 13 points were classified as high-quality indicator compliance centers.

Efficacy and Safety of Sodium Glucose Cotransporter-2 (SGLT2) Inhibitors in Patients With Diabetes and Chronic Kidney Disease (CKD): A Meta-analysis of Randomized Control Trials.

The current meta-analysis aims to assess the efficacy and safety of sodium glucose cotransporter 2 (SGLT2) inhibitors in individuals with diabetes and chronic kidney disease (CKD). The current meta-analysis was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A systematic search was conducted to identify all relevant studies related to the efficacy and safety of SGLT2 inhibitors in individuals with diabetes and CKD.

Viral Infection Model with Diffusion and Distributed Delay: Finite-Dimensional Global Attractor.

We study a virus dynamics model with reaction-diffusion, logistic growth terms and a general non-linear infection rate functional response. The model has a distributed delay, including the case of state-selective delay. We construct a dynamical system in a Hilbert space and prove the existence of a finite-dimensional global attractor.

Traumatic Carotid Cavernous Fistula Resulting in Symptoms in the Ipsilateral Eye: A Case Report.

Post-traumatic unilateral carotid cavernous fistula (CCF) with ipsilateral symptoms is a rare occurrence, so its diagnosis frequently gets overlooked for other more common conditions. Timely imaging with digital subtraction angiography (DSA) and appropriate vascular intervention is essential in preventing potentially serious sequelae in such cases. We describe a case of post-traumatic CCF in a 42-year-old man who experienced intermittent headaches and right eye redness, proptosis, and watery discharge for three months following the incident.

HETEROGENEITY OF CLINICAL MANIFESTATIONS OF HYPERPROLACTINEMIA (REVIEW AND OWN OBSERVATIONS).

The article is devoted to the features of the clinical picture of hyperprolactinemia, which can be partially determined by both gender and age of patients. Along with the well-known "classic" manifestations of hyperprolactinemiс syndrome, such as clinical signs of hypogonadism and mechanical pressure of the pituitary tumor on adjacent anatomical structures, there are others that are poorly known to a wide range of practicing physicians. Less frequent manifestations of hyperprolactinemia include the development of hypopituitarism, osteoporosis or osteopenia, alopecia.

Evolutionary allometry and ecological correlates of fang length evolution in vipers.

Traits for prey acquisition form the phenotypic interface of predator-prey interactions. In venomous predators, morphological variation in venom delivery apparatus like fangs and stingers may be optimized for dispatching prey. Here, we determine how a single dimension of venom injection systems evolves in response to variation in the size, climatic conditions and dietary ecology of viperid snakes.

Synthesis, docking, and biological evaluation of novel 1-benzyl-4-(4-(R)-5-sulfonylidene-4,5-dihydro-1H-1,2,4-triazol-3-yl)pyrrolidin-2-ones as potential nootropic agents.

In order to search for innovative nootropic agents, new 1-benzyl-4- (4- (R)-5-sulfonylidene-4,5-dihydro-1H-1,2,4-triazol-3-yl) pyrrolidine-2-ones was synthesized by reacting benzylamine with itaconic acid to 1-benzyl-5-oxopyrrolidine-3-carboxylic acid, which was then subjected to hydrazinolysis followed by the addition of substituted isothiacyanate followed by cyclization of intermediate thiosemicarbazides. The structure and purity of the obtained substances were confirmed by elemental analysis, H NMR spectroscopy, C NMR spectroscopy and LC/MS. Docking studies were performed for the substances synthesized using Autodock 4.

Stability of Aqueous Suspensions of COOH-Decorated Carbon Nanotubes to Organic Solvents, Esterification, and Decarboxylation.

Carbon nanotubes are among the most widely used nanosystems, and stability of carbon nanotube suspensions is critical for nanotechnology and environmental science. Remaining in aqueous environment alone misses important factors that regulate colloidal stability in the presence of electrolytes. Indeed, introduction of (80-95) vol % organic solvents leads to sharp changes in suspension properties depending on the solvent.

Frustrations of supported catalytic clusters under operando conditions predicted by a simple lattice model.

The energy landscape with a number of close minima separated by low barriers is a well-known issue in computational heterogeneous catalysis. In the framework of the emerging out-of-equilibrium material science, the navigation through such involved landscapes is associated with the functionality of materials. Current advancements in the cluster catalysis has brought and continues to bring essential nuances to the topic.

Estimation of Nanoparticle's Surface Electrostatic Potential in Solution Using Acid-Base Molecular Probes. III. Experimental Hydrophobicity/Hydrophilicity and Charge Distribution of MS2 Virus Surface.

MS2 bacteriophage is often used as a model for evaluating pathogenic viruses' behavior in aqueous solution. However, the questions of the virus surface's hydrophilic/hydrophobic balance, the charge distribution, and the binding mechanism are open. Using the dynamic light scattering method and laser Doppler electrophoresis, the hydrodynamic diameter and the ζ-potential of the virus particles were measured at their concentration of 5 × 10 particles per mL and ionic strength 0.

Peculiarities of the Phase Formation during Electroconsolidation of AlO-SiO-ZrO Powders Mixtures.

This paper is devoted to the sintering process of AlO-SiO-ZrO ceramics. The studied method was electroconsolidation with directly applied electric current. This method provides substantial improvements to the mechanical properties of the sintered samples compared to the traditional sintering in the air.

Current War in Ukraine: Lessons from the Impact of War on Combatants' Mental Health during the Last Decade.

Ukrainian Military Hospital retrospective analysis during a decade of conflicts (3995 records) unveils specific mental health ICD-10-CM distribution per rank and the long-lasting impact of active conflict or trench warfare. Most hospitalizations in all years of observation were among soldiers. Anxiety-related disorders have been present since 'peacetime', mainly among professional soldiers and high ranks, pointing to the need for rank-tailored psychological training in skills to reduce the anxiety burden.

Crystal structure, Hirshfeld surface analysis and geometry optimization of 2-hy-droxy-imino--[1-(pyrazin-2-yl)ethyl-idene]propano-hydrazide.

In the mol-ecule of the title compound, CHNO, the oxime and hydrazide groups are situated in a -position in relation to the C-C bond linking the two functional groups. The CHC(=NOH)C(O)NH fragment deviates from planarity because of a twist between the oxime and amide groups. In the crystal, mol-ecules are linked by O-H⋯O hydrogen bonds, forming zigzag chains in the [013] and [03] directions.

Synthesis, X-ray diffraction study, analysis of inter-molecular inter-actions and mol-ecular docking of ethyl 1-(3-tosyl-quinolin-4-yl)piperidine-4-carboxyl-ate.

The title compound, CHNOS, can be obtained two synthetic routes. According to our investigations, the most suitable way is by the reaction of ethyl 2-bromo-acetate with sodium tosyl-sulfinate in dry DMF. It was crystallized from methanol into the monoclinic 2/ space group with a single mol-ecule in the asymmetric unit.

Global patterns in endemicity and vulnerability of soil fungi.

Fungi are highly diverse organisms, which provide multiple ecosystem services. However, compared with charismatic animals and plants, the distribution patterns and conservation needs of fungi have been little explored. Here, we examined endemicity patterns, global change vulnerability and conservation priority areas for functional groups of soil fungi based on six global surveys using a high-resolution, long-read metabarcoding approach.

Threshold conditions for transversal modes of tunable plasmonic nanolasers shaped as single and twin graphene-covered circular quantum wires.

We implement the lasing eigenvalue problem (LEP) approach to study the electromagnetic field in the presence of a circular quantum wire (QW) made of a gain material and wrapped in graphene cover and a dimer of two identical graphene-covered QWs, at the threshold of stationary emission. LEP delivers the mode-specific eigenvalue pairs, namely the frequencies and the threshold values of the QW gain index for the plasmon and the wire modes of such nanolasers. In our analysis, we use quantum Kubo formalism for the graphene conductivity and classical Maxwell boundary-value problem for the field functions.

Local Structure of DMF-Water Mixtures, as Seen from Computer Simulations and Voronoi Analysis.

Molecular dynamics simulations of mixtures of ,-dimethylformamide (DMF) with water of various compositions, covering the entire composition range, are performed on the canonical (,,) ensemble. The local structure of the mixtures is analyzed in terms of radial distribution functions and the contributions of the first five neighbors to them, various order parameters of the water molecules around each other, and properties of the Voronoi polyhedra of the molecules. The analyses lead to the following main conclusions.

Ca -dependent interactions between lipids and the tumor-targeting peptide pHLIP.

Cancerous tissues undergo extensive changes to their cellular environments that differentiate them from healthy tissues. These changes include changes in extracellular pH and Ca concentrations, and the exposure of phosphatidylserine (PS) to the extracellular environment, which can modulate the interaction of peptides and proteins with the plasma membrane. Deciphering the molecular mechanisms of such interactions is critical for advancing the knowledge-based design of cancer-targeting molecular tools, such as pH-low insertion peptide (pHLIP).

The high diversity of gametogenic pathways in amphispermic water frog hybrids from Eastern Ukraine.

Interspecific hybridization can disrupt canonical gametogenic pathways, leading to the emergence of clonal and hemiclonal organisms. Such gametogenic alterations usually include genome endoreplication and/or premeiotic elimination of one of the parental genomes. The hybrid frog exploits genome endoreplication and genome elimination to produce haploid gametes with chromosomes of only one parental species.

CeO2 nanoparticles improve prooxidant/antioxidant balance, life quality and survival of old male rats.

Due to its unique redox chemistry, nanoceria is considered as potent free radical scavenger and antioxidant. However, their protective capacity in aging organisms remains controversial. To detect the anti-aging effects associated with the redox activity of 2 and 10 nm nano-CeO2, different test systems were used, including in vitro analysis, in situ assay of mitochondria function and in vivo studies of suitable nano-CeO on aging of male Wistar rats from 22 months-old to the end of life.