230 results match your criteria: "Uveitis Anterior Nongranulomatous"
Patterns and Outcomes of Pediatric Uveitis in a University-Based Tertiary Referral Center in Riyadh, Saudi Arabia.
Ocul Immunol Inflamm
December 2024
Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Article Synopsis
- The study aimed to analyze the patterns and outcomes of uveitis in children through a retrospective patient review.
- A total of 184 pediatric patients were examined, revealing that panuveitis was the most common type, with a significant number displaying non-granulomatous and non-infectious uveitis.
- After one year, most patients (85.4%) had improved vision, achieving at least 20/40 visual acuity, and Vogt-Koyanagi-Harada disease was identified as the most prevalent specific diagnosis.
Ibrutinib-Related Uveitis in Non-Hodgkin Lymphoma Patients: A Case Report and Literature Review.
Ocul Immunol Inflamm
October 2024
Ophthalmology Interest Group, Neuroscience (NEUROS) Research Group, Neurovitae Research Center, Institute of Translational Medicine (IMT), Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogotá, Colombia.
Purpose: To report two cases of ibrutinib-related uveitis and review the literature to date.
Methods: We report two cases of ibrutinib-related uveitis using CARE guidelines and review the cases reported in the literature.
Results: Case 1) A 55-year-old female with recurrent primary central nervous system lymphoma presented with bilateral decreased visual acuity, photophobia, and floaters that started one month after initiating oral treatment with ibrutinib.
Biologics in ocular inflammatory diseases - Experience from a tertiary referral eye care center in South India.
Indian J Ophthalmol
September 2024
Department of Rheumatology, Manipal Hospitals, Millers Road, Bengaluru, Karnataka, India.
Article Synopsis
- The study evaluated the effectiveness of biologic treatments for noninfectious uveitis and other eye inflammatory diseases in a South Indian population over several years.
- A total of 76 patients, predominantly adults with anterior nongranulomatous uveitis, were analyzed, revealing adalimumab as the most frequently used biologic.
- While biologics led to a significant reduction in flare-ups, their success rates were lower for certain conditions, particularly in younger patients with specific types of uveitis.
Management of JIA associated uveitis.
Best Pract Res Clin Rheumatol
September 2024
Department of Paediatric Rheumatology, Bristol Royal Hospital for Children, Bristol, UK; Translational Health Science, University of Bristol, Bristol, UK. Electronic address:
Article Synopsis
- Juvenile Idiopathic Arthritis (JIA) is a common chronic childhood condition that can lead to uveitis in 20-25% of cases, requiring regular screening for early detection.
- Uveitis is typically chronic, asymptomatic, and involves inflammation in the front part of the eye, making collaboration between paediatric rheumatologists and ophthalmologists essential for effective management.
- Treatment usually begins with methotrexate, and if ineffective, may progress to adalimumab, with alternative options like anti-IL6 and anti-TNF agents available for persistent cases, though evidence for these is limited.
Case report: A severe case of zoledronate-associated diffuse orbital inflammation and uveitis in a patient with metastatic breast cancer.
Front Ophthalmol (Lausanne)
April 2024
Department of Ophthalmology, University of Ottawa, Ottawa, ON, Canada.
Introduction: Zoledronate is a commonly prescribed medication to maintain bone health; however, a rare side effect includes ocular inflammation. We report a case of simultaneous anterior uveitis and orbital inflammation associated with zoledronate infusion in a patient with metastatic breast cancer. We also performed a literature search to provide an up-to-date summary of cases with zoledronate-associated ocular inflammation.
View Article and Find Full Text PDFAcute Noninfectious Anterior Ocular Inflammation Following Ranibizumab Biosimilar Intravitreal Injection in a Patient With Recent COVID-19 Vaccination.
Cureus
May 2024
Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, JPN.
Article Synopsis
- The text discusses the potential risks associated with the timing of intravitreal anti-VEGF injections and COVID-19 vaccinations, particularly concerning ocular inflammation.
- A case study is presented involving a 74-year-old man who developed acute noninfectious anterior ocular inflammation after receiving a COVID-19 vaccine and an anti-VEGF injection.
- The patient experienced blurred vision and inflammation in his left eye, but further exams ruled out serious complications, indicating that more awareness about the interaction between these procedures is necessary.
Uveitis Profile in Children and Its Impact on Vision at Queen Rania Children's Hospital.
Cureus
April 2024
Immunology, Allergy, and Rheumatology, Queen Rania Children's Hospital, Amman, JOR.
Aim: The aim of this study was to explore the patterns of pediatric uveitis and the types of ocular complications of uveitis and to determine the possible risk factors associated with visual impairment.
Method: This was a cross-sectional study conducted at Queen Rania Children's Hospital between June 2020 and June 2023. All children diagnosed with uveitis were enrolled in the study.
Treatment of uveitis and scleritis patients in Malaysia.
Int J Ophthalmol
March 2024
Department of Ophthalmology, Faculty of Medicine and Defence Health, National Defence University of Malaysia, Kuala Lumpur 57000, Malaysia.
Aim: To determine the common causes and visual outcome after treatment among uveitis and scleritis patients.
Methods: This is a retrospective cohort observational study. All consecutive clinical records of patients with newly diagnosed uveitis and scleritis over a 4-year period, from Jan.
Autoimmune Liver Disease Associated Uveitis: An Extrahepatic Manifestation or a Polyautoimmunity Phenomenon? Case Reports.
Ocul Immunol Inflamm
November 2024
Ophthalmology Interest Group, Neuroscience (NEUROS) Research Group, Neurovitae Research Center, Institute of Translational Medicine (IMT), Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogotá, Colombia.
Purpose: To report two cases of non-granulomatous unilateral anterior uveitis in two female patients associated with autoimmune liver diseases (ALD), emphasizing the possibility of this rare coexistence as a polyautoimmunity phenomenon.
Case Descriptions: Case 1: An 18-year-old female with a history of congenital renal hypoplasia and metabolic syndrome presented with anterior uveitis in OS and a history of jaundice, blood elevated hepatic enzymes, and cholangioresonance compatible with primary sclerosing cholangitis (PSC). Laboratory work-up for additional autoimmune and infective causes were within normal limits.
Epidemiology, clinical features, and classification of 3,404 patients with uveitis: Colombian Uveitis Multicenter Study (COL-UVEA).
Graefes Arch Clin Exp Ophthalmol
August 2024
Clínica de Oftalmología Sandiego, Medellín, Colombia.
Article Synopsis
- * A total of 3,404 patient records were reviewed, showing a mean diagnosis age of 41.1 years, with a majority being women; the most common types of uveitis were unilateral, acute, and non-granulomatous, primarily affecting the anterior segment of the eye.
- * Findings highlight idiopathic as the leading cause of uveitis, underlining the importance of ongoing research to adapt diagnosis and treatment strategies for these inflammatory eye conditions.
Targeted therapies for uveitis in spondyloarthritis: A narrative review.
Joint Bone Spine
September 2024
Department of Internal Medicine, Hospices Civils de Lyon, Hôpital Universitaire de la Croix-Rousse, University Claude-Bernard Lyon 1, Lyon, France; Inserm U1290, Research on Healthcare Performance (RESHAPE), University Claude-Bernard Lyon 1, Lyon, France.
Article Synopsis
- Spondyloarthritis (SpA) is a group of chronic inflammatory joint disorders that can cause acute uveitis, affecting vision with symptoms like pain and redness in the eye.
- Most patients experience episodes of uveitis but maintain good vision; however, systemic treatments are advised for those with frequent flare-ups or severe complications.
- Advances in understanding SpA have led to targeted therapies like TNF inhibitors, showing promising results, while other biologics may vary in efficacy, highlighting the need for collaboration among healthcare providers for effective management.
Long-term follow-up of a healthy man with endogenous Streptococcus anginosus endophthalmitis.
J Ophthalmic Inflamm Infect
February 2024
Department of Ophthalmology, Hadassah Medical Center, Jerusalem, Israel.
We report the long-term follow-up of an immunocompetent patient who presented with slowly progressive endogenous endophthalmitis secondary to Streptococcus anginosus. A 46-year-old healthy man presented with a two-month history of right eye iritis. On examination, visual acuity was 20/60 with intraocular pressure of 6 mm Hg.
View Article and Find Full Text PDFLeptospiral Uveitis: Case Series and Review of Literature.
Ocul Immunol Inflamm
October 2024
Retina Services, Neoretina Eyecare Institute, Hyderabad, India.
Aim: To present the clinical features and review of literature of leptospiral uveitis.
Methods: We present clinical features of patients with leptospiral uveitis with positive Leptospira IgM antibodies.
Results: Twenty-six eyes of 24 patients, 11 males (45.
Confocal Microscopy, Anterior Segment Optical Coherence Tomography and Clinical Findings in a Non-Granulomatous Uveitis Case for Mpox Infection.
Ocul Immunol Inflamm
October 2024
Department of Ophthalmology, School of Medicine Universidad Nacional de Colombia, Bogotá, Colombia.
Article Synopsis
Case Report: Spectrum of interesting ocular manifestations following COVID-19 vaccination: a case series of real-world presentations.
Front Cell Infect Microbiol
November 2023
Department of Ophthalmology, Oasis Eye Specialists, Kuala Lumpur, Malaysia.
Article Synopsis
Prevalence and clinical characteristics of uveitic glaucoma: multicentric study in Bogotá, Colombia.
Eye (Lond)
March 2024
Neuroscience (NEUROS) Research Group, Neurovitae Research Center, Institute of Translational Medicine (IMT), Universidad Del Rosario Escuela de Medicina y Ciencias de la Salud, Bogotá, Colombia.
Article Synopsis
- - The study aimed to identify the clinical features of patients with uveitic glaucoma (UG) and ocular hypertension secondary to uveitis (OHT-SU) by analyzing medical records from 2013 to 2021.
- - Among 660 patients with uveitis, 28.9% had OHT-SU and 16.4% developed UG, with females being more affected than males, especially in group-specific age ranges.
- - The findings suggest UG and OHT-SU are prevalent in the Colombian population, with a recommendation for earlier treatment to improve visual outcomes, as 81.1% of patients received topical hypotensive therapy and some required surgical intervention.
Diagnostic and Management Strategies of Tubulointerstitial Nephritis and Uveitis Syndrome (TINU): Current Perspectives.
Clin Ophthalmol
September 2023
Department of Ophthalmology, Rey Juan Carlos University Hospital, Madrid, Spain.
Article Synopsis
- TINU syndrome is a rare autoimmune disease that involves both kidney (tubulointerstitial nephritis) and eye (uveitis) issues, and its cause may involve genetic and environmental factors.
- Diagnosis can be difficult since kidney and eye symptoms can appear at different times; doctors must rule out other conditions to confirm it.
- The main treatment options include corticosteroids and immunosuppressive drugs, but relapses are common, making effective management challenging.
Trabeculectomy with ExPress - an effective solution to Posner-Schlossman syndrome.
Folia Med (Plovdiv)
August 2023
Medical University of Plovdiv, Plovdiv, Bulgaria.
Article Synopsis
Post-COVID-19 vaccine uveitis: A case series.
J Fr Ophtalmol
September 2023
Department of Ophthalmology, McMaster University, Ontario, Canada.
Article Synopsis
- A case series was conducted to explore potential uveitis (inflammation of the eye) after receiving the Pfizer and Moderna COVID-19 vaccines, as there is limited information about this side effect.
- Eight patients with uveitis symptoms developed their conditions within 14 days of vaccination, with most experiencing symptoms after the first dose and a mean onset of 5.19 days post-vaccine.
- The study aims to enhance understanding of the relationship between COVID-19 vaccines and uveitis, emphasizing the importance for physicians to recognize and treat these ocular complications as vaccination rates increase.
Behçet's disease uveitis.
Rev Med Interne
October 2023
Department of Internal Medicine and Clinical Immunology, centre de référence des maladies auto-immunes systémiques rares, centre de référence des maladies auto-inflammatoires et de l'amylose inflammatoire, Sorbonne universités, Pitié-Salpêtrière University Hospital, AP-HP, Inserm, UMR_S 959, 83, boulevard de l'Hôpital, 75013 Paris, France. Electronic address:
Article Synopsis
- The condition can manifest as anterior, posterior, or panuveitis, with panuveitis being the most common type, especially in men, and may appear as an initial symptom in 20% of patients or several years later.
- Management focuses on quickly resolving inflammation, preventing future episodes, achieving remission, and protecting vision, with recent advances in biologic therapies showing promise in treatment strategies.
Rise of biologics in noninfectious uveitis: a retrospective cohort study from Nepal.
Ann Med Surg (Lond)
May 2023
Department of Internal Medicine, Maharajgunj Medical Campus, Institute of Medicine, Kathmandu.
Article Synopsis
- Uveitis is a serious eye condition that can severely impact one's quality of life, but recent advances in treatment, especially with biologics, have made a significant difference.
- Biologics, like tumor necrosis factor-α inhibitors and other specific inhibitors, are particularly effective for noninfectious uveitis when traditional treatments fail or are poorly tolerated.
- A study of 10 patients demonstrated that most responded positively to biologic treatments, with no recurrences noted after a year of follow-up.
Long-term follow-up of acute retinal necrosis with retinal detachment secondary to herpes simplex virus type 2 with a successful visual outcome.
BMJ Case Rep
April 2023
Vitreo-retina, Narayana Nethralaya, Bengaluru, Karnataka, India.
Article Synopsis
Bilateral nongranulomatous anterior uveitis in a patient with recurrent NTM pneumonia: A rare presentation of adult-onset immunodeficiency.
J Fr Ophtalmol
October 2023
Department of Medicine, Suddhavej Hospital, Faculty of Medicine, Mahasarakham University, Thailand. Electronic address: