Homeotic transformation of tail to limbs: A novel morphogenesis in the framework of self-organization and reprogramming of cell fate during appendage regeneration.

Homeotic transformation of tail to hindlimbs in anuran tadpoles is a manifestation of the reprogramming of positional information in the event of tail regeneration. Such discovery of homeosis is of particular interest considering its occurrence in a vertebrate under the influence of a morphogen which represents a self-organizing system in the context of developmental and regenerative studies. This article reviews homeotic transformation of tail to hindlimbs including pelvic girdles induced by retinoic acid (RA) /vitamin A palmitate during tail regeneration under the scope of self-organization and the role of blastema as an organizer.

Characterization of extracellular chitin deacetylase from isolated from marine crustacean shell.

Chitosan is a promising biopolymer with wide range of applications. It is the deacetylated product of chitin. Commercially, it is produced from chitin via a harsh thermochemical process that has several shortcomings and heterogenous deacetylation product.

Energy conservation or expense? A possible dilemma under combined stresses of salinity and submergence in rice.

Salinity and flooding are two major production impediments affecting rice cultivation in coastal agro-ecosystems. We investigated how rice plants use two contrasting strategies such as energy conservation (for submergence tolerance) and energy expenditure (for ion exclusion) to adapt to the combined stresses of saline water submergence (SWS). Pot and hydroponic experiments were conducted using four selected rice genotypes carrying Sub1 (Submergence1) and/or Saltol (Salinity tolerance) QTLs in their genetic background and exposed them to salinity and submergence stresses individually and combined under controlled experimental conditions.

Improved Adsorption of Organic Dyes onto a Polypyrrole/Tannic Acid Nanocomposite.

Methyl orange (MO) and methylene blue (MB) dyes are toxic and carcinogenic; thus, their presence in water bodies has been a major concern. Designing an efficient adsorbent for removal of these dyes is a scientific challenge for researchers. In this work, a polypyrrole-tannic acid nanocomposite was prepared via a chemical oxidation method and used as a novel adsorbent for removing these toxic dyes.

Dietary interventions in mitigating the impact of environmental pollutants on Alzheimer's disease - A review.

Numerous studies linking environmental pollutants to oxidative stress, inflammation, and neurotoxicity have assigned pollutants to several neurodegenerative disorders, including Alzheimer's disease (AD). Heavy metals, pesticides, air pollutants, and endocrine disruptor chemicals have been shown to play important roles in AD development, with some traditional functions in amyloid-β formation, tau kinase action, and neuronal degeneration. However, pharmacological management and supplementation have resulted in limited improvement.

Pesticide pollution: toxicity, sources and advanced remediation approaches.

The Food and Agricultural Organization of the United Nations (FAO) estimates that food production must rise by 70% to meet the demands of an additional 2.3 billion people by 2050. This forecast underscores the persistent reliance on pesticides, making it essential to assess their toxicity and develop effective remediation strategies.

Biofilm Demolition by [Au(N N)Cl(NHC)][PF] Complexes Fastened with Bipyridine and Phenanthroline Ligands; Potent Antibacterial Agents Targeting Membrane Lipid.

The development of new antibacterial drugs is essential for staying ahead of evolving antibiotic resistant bacterial (ARB) threats, ensuring effective treatment options for bacterial infections, and protecting public health. Herein, we successfully designed and synthesized two novel gold(III)- NHC complexes, [Au(1)(bpy)Cl][PF] (2) and [Au(1)(phen)Cl][PF] (3) based on the proligand pyridyl[1,2-a]{2-pyridylimidazol}-3-ylidene hexafluorophosphate (1⋅HPF) [bpy=2,2'-bipyridine; phen=1,10-phenanthroline]. The synthesized complexes were characterized spectroscopically; their geometries and structural arrangements were confirmed by single crystal XRD analysis.

The multifaceted role of different SnRK gene family members in regulating multiple abiotic stresses in plants.

Abiotic stresses are a major constraint for agricultural productivity and food security in today's era of climate change. Plants can experience different types of abiotic stresses, either individually or in combination. Sometimes, more than one stress event may occur simultaneously or one after another during the lifecycle of the plant.

Mechanism of betterment towards growth and induction of defense in rice (Oryza sativa L.) by biopriming with bacterial endophytes isolated from wild rice.

Utilizing beneficial microorganisms associated with plants, particularly endophytes, is becoming more and more prevalent since it supports the physiological health and evolutionary adaption of the host. The range of enhanced endophytic bacteria found in wild rice makes it a promising resource for sustainable agriculture. Current study focused on benefits of bacterial endophytes isolated from tissues of wild rice plants' roots, stems, and leaves for managing the health and development of rice (Oryza sativa L.

Smear layer removal and antimicrobial efficacy of chitosan as a root canal irrigant: a systematic review of in-vitro studies.

This systematic review was designed to answer the following question: Does chitosan provide better smear layer removal and antimicrobial efficacy than other root canal irrigants? A literature search was done using electronic databases PubMed, Scopus, Web of Science, Cochrane Library, EBSCO host, Grey Literature Report, and Open Grey from inception to June 18, 2024. The reference lists of included articles were also hand-searched. Two reviewers independently assessed the studies' eligibility based on the inclusion and exclusion criteria and performed data extraction.

Trend, Pattern, and Prevalence of Adverse Pregnancy Outcomes among Women of Reproductive Age in India, 1992-2021.

Background: Adverse pregnancy outcomes (APOs) are the most important vital statistics used to assess maternal health and child health statistics. They are an indicator of the quality of maternal and child health care services, i.e.

Nanoquercetin based nanoformulations for triple negative breast cancer therapy and its role in overcoming drug resistance.

Triple Negative Breast Cancer (TNBC) is a highly aggressive and treatment-resistant subtype of breast cancer, lacking the expression of estrogen, progesterone, and HER2 receptors. Conventional chemotherapy remains the primary treatment option, but its efficacy is often compromised by the development of drug resistance. Nanoquercetin has garnered the attention of researchers due to its potential in combating cancer.

Shining light on environmental remediation: a type-II heterojunction MnFeO/rGO nanocomposites for enhanced photocatalytic degradation of organic dyes and bisphenol A.

In this study, the pressing issue of persistent organic pollutants in wastewater was addressed by designing and fabricating a magnetically separable MnFeO/rGO heterostructure catalyst for efficient mineralization of bisphenol A (BPA) and dyes such as alizarin red S (anionic) and malachite green (cationic), which are known for their resistance to biodegradation and carcinogenic properties. Comprehensive structural and surface analyses using XRD, XPS, SEM, and TEM/HRTEM coupled with magnetic and optical property measurements revealed the formation of the MnFeO/rGO heterostructures. Among all, the MnFeO/rGO-10 catalyst with 10% wt% of rGO exhibited 100% efficiency in the mineralization of BPA and both dyes under visible light illumination within 60 min.

Reporting of gridded ammonia emission and assessment of hotspots across India: A comprehensive study of 24 anthropogenic sources.

Ammonia (NH) acts as a key precursor of the particulate matter, could reduce visibility, deplete stratospheric ozone, and trigger perturbation in ecosystems. Being an agrarian country with a large livestock population and uncontrolled fertilizer application, India could be accountable as a major stakeholder of global NH emissions. This study developed a comprehensive gridded (0.

Synthesis, SAR, and application of JQ1 analogs as PROTACs for cancer therapy.

JQ1 is a wonder therapeutic molecule that selectively inhibits the BRD4 signaling pathway and is thus widely used in the anticancer drug discovery program. Due to its unique selective BRD4 binding property, its applications are further extended in the design and synthesis of bi-functional PROTAC molecules. This BRD4 targeting PROTAC molecule selectively degrades the protein by proteolysis.

Fabrication and characterization of natural fiber reinforced cowpea resin-based green composites: an approach towards agro-waste valorization.

A paradigm shift towards using bio-resins or bio-derived resins among materials scientists has led to wide exploration of the sector. Polymers such as soy protein isolate, poly(hydroxy alkanoate), poly(lactic acid), and thermoplastic starch are all synthetically modified bio-based resins and are costly. The cowpea-derived resin with the least chemical modification was used in this study as a matrix for the formation of composites with natural fibers at a lesser cost.