Pathol Res Pract
December 2024
Nitte (Deemed To Be University), KS Hegde Medical Academy (KSHEMA), Department of obstetrics and gynecology, India; Nitte (Deemed To Be University), KS Hegde Medical Academy (KSHEMA), KSHEMA IVF Fertility & Reproductive Medicine Centre India, India.
Uterine Fibroids (UF) are the most common (about 70 % cases) benign gynecological smooth muscle tumors of the uterus in women of reproductive age, characterized by abnormal cholesterol, lipoproteins, and triglyceride levels, and are a major public health concern. Despite its high prevalence, this condition remains complex and poorly understood. These tumors are hormone-dependent and hormones and lipid levels are inversely related.
View Article and Find Full Text PDFSAGE Open Med Case Rep
December 2024
Department of Pathology, School of Medicine, Wollega University, Nekemte City, Oromia Regional State, Ethiopia.
Uterine fibroids are benign tumors, arising from uterine smooth muscle cells. They are one of the most common benign tumors of the female genital tract among childbearing women, occurring in 20%-50% of women of reproductive age. The association of uterine myomas with pregnancy is high.
View Article and Find Full Text PDFCureus
November 2024
Obstetrics and Gynecology, Konan Medical Center, Kobe, JPN.
We present the first case of low-grade endometrial stromal sarcoma (ESS) invading a leiomyoma, which was difficult to diagnose preoperatively. A 49-year-old multiparous woman was referred to our institution due to the enlargement of an old leiomyoma after menopause. Transvaginal ultrasonography revealed a 40-mm lesion in the myometrium of the uterine body with calcification and edema.
View Article and Find Full Text PDFRadiol Case Rep
February 2025
Radiology Department of Surgery, Medicine and Pharmacy, University of Sassari, Viale S. Pietro, Sassari, Italy.
Primary pelvic peritoneal masses, not arising from major organs, are uncommon in adults. Leiomyomas are a group of benign smooth muscle tumors, most commonly found in the uterus in premenopausal women (70-80%). Extra-uterine locations are very rare and more frequent in women.
View Article and Find Full Text PDFCureus
November 2024
Medical Oncology, Tata Main Hospital, Jamshedpur, IND.
J Midlife Health
October 2024
Department of Pathology, Esic Medical College and Hospital, Faridabad, Haryana, India.
Cureus
October 2024
Obstetrics and Gynecology, Watim Medical and Dental College, Islamabad, PAK.
Uterine fibroids are benign smooth muscle tumors of the uterus, are relatively common in reproductive-age women, and are associated with increasing maternal age. This case study details a 37-year-old female patient who was incidentally diagnosed with a larger lower segment fibroid during her first pregnancy scan and responded well to treatment, delivered by a cesarian due to transverse lie and lower uterine segment fibroid completely obstructing the birth canal.
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October 2024
Medical Records Statistics Division, Deyang People's Hospital, Deyang, Sichuan, China.
Intravenous leiomyomatosis (IVL), an abnormal growth pattern of uterine leiomyomas, is a rare tumor characterized by masses of smooth muscle cells appearing histologically benign and proliferating within the blood vessels but not invading the tissue. Currently, there have been limited reports of early cases of IVL, and the imaging characteristics of IVL remain uncertain, resulting in frequent misdiagnosis prior to surgery. The present study utilized a case of early IVL detected through conventional ultrasound and subsequently confirmed contrast-enhanced ultrasound (CEUS) to further investigate ultrasound's diagnostic efficacy for early IVL detection.
View Article and Find Full Text PDFGenes Chromosomes Cancer
November 2024
Department of Pathology, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China.
With no more than two dozen cases reported in the literature, malignant peripheral nerve sheath tumor (MPNST) is a rare primary mesenchymal neoplasm arising in the female genital tract. Most cases occurred in middle-aged adults with high grade histology, unfavorable clinical outcome, and no history of neurofibromatosis type 1. Its extreme rarity in this site no doubt poses a diagnostic challenge during routine clinical practice.
View Article and Find Full Text PDFIntroduction Endometrial cancer, one of the most prevalent gynecological malignancies, represents a significant contributor to global mortality and morbidity. The histological subtype of this cancer is pivotal in treatment planning and patient risk stratification. This case series, comprising seven cases, underscores the significance of rare endometrial cancer variants and the importance of ancillary studies, specifically immunohistochemistry, in comprehending and diagnosing the condition.
View Article and Find Full Text PDFMedicina (Kaunas)
October 2024
Institute of Medical Science, Gyeongsang National University, Jinju 52727, Republic of Korea.
Tunis Med
October 2024
Emergency Department Maternity and neonatology center of Tunis, Tunis, Tunisia. Faculty of medicine of Tunis, university Tunis el manar Tunisia.
Introduction: Intravenous leiomyomatosis (IVL), a rare type of uterine leiomyoma (its incidence is about 0.25% to 0.40% of patients who present uterine fibroma), is characterized by the formation and growth of benign leiomyoma tissue within the vascular wall or lymphatic lumen.
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September 2024
Obstetrics and Gynecology, Assisted Reproduction in Gynecology Center, London, GBR.
Ann Pathol
October 2024
Département de biopathologie, institut Bergonié, Bordeaux, France; Unité Inserm 1312, Bordeaux, France.
This review focuses on uterine mesenchymal tumors that are defined on a molecular level by a single and unique genetic alteration, that is somehow necessary and sufficient to allow tumor growth and progression. Although diverse from a clinical, morphological and immunohistochemical point of view, the different entities we are going to talk about share both a simple genomic profile with a low number of chromosomal alterations observed by CGH Array (few deletions, gains or amplifications..
View Article and Find Full Text PDFAm J Reprod Immunol
October 2024
Guangzhou Key Laboratory of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Case Rep Oncol Med
September 2024
Reproductive Endocrinology and Infertility Fakih Medical Center, Al Ain, UAE.
Uterine leiomyomas are a frequent finding in women of reproductive age. However, rare, unusual growth patterns exist, such as atypical, cellular, mitotically active, myxoid, and epithelioid leiomyomas, and present a major concern as they mimic highly malignant uterine tumors such as uterine leiomyosarcomas. An example of such cases is the epithelial type leiomyoma which is the subject of our report in a 35-year-old female.
View Article and Find Full Text PDFJ Int Med Res
September 2024
Department of CT Examination, Shengli Oilfield Central Hospital, Dongying, Shandong, China.
Rare Tumors
September 2024
Department of Surgery, University of Calabar/University of Calabar Teaching Hospital, Calabar, Nigeria.
Clin Med Insights Case Rep
September 2024
Department of Obstetrics and Gynecology, Bayelsa Medical University, Yenagoa, Bayelsa State, Nigeria.
Background: Uterine fibroids, or Leiomyoma is a type of Smooth Muscle Tumors of the uterus (SMTs) and are common in the black race. Giant uterine fibroids, on the other hand, are uncommon and may occur during patient dissimulation. Dissimulation may occur because of a dread of surgery and hospitals visits, fear of surgical death, chronic intake of herbal concussion, and a religio-traditional strong belief system on instant healing following prayers, among others.
View Article and Find Full Text PDFOchsner J
January 2024
Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Case Rep Pathol
September 2024
Department of Pathology and Laboratory Medicine King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.
Low-grade endometrial stromal sarcomas (LGESSs) are indolent tumors with a slow progression rate that tend to recur locally. They represent up to 10% of all primary sarcomas of the uterus and endometrium and only 0.2% of all genital tract tumors.
View Article and Find Full Text PDFCureus
July 2024
Radiodiagnosis, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Leiomyosarcoma (LMS) is an extremely rare malignant pathology affecting smooth muscle cells, with the uterus being the predominant location of LMS. Its occurrence in the duodenum is rare, making it a diagnostic challenge for radiologists. Patients with duodenal LMS can present with very vague symptoms such as abdominal discomfort, loss of weight, or manifestations associated with internal gastrointestinal bleeding.
View Article and Find Full Text PDFAm J Case Rep
August 2024
Department of Anatomopathology, Epicura Hospital, Hornu, Belgium.
Cureus
July 2024
Department of Obstetrics and Gynecology, Narendra Kumar Prasadrao (NKP) Salve Institute of Medical Sciences and Research Centre, Nagpur, IND.
The most common benign neoplastic uterine tumors that grow monoclonally from the smooth muscle cells of the uterus are uterine fibroids or leiomyomas, which may occur as a single lesion or as multiple lesions with variation in size from microscopic to large macroscopic extent. The majority are diagnosed in the preclinical routine reliably, despite challenges due to the possibility of multiple differential diagnoses. Hence, this report highlights a case of a postmenopausal female of 53-year-old working as a staff nurse at the same hospital and who visited the outpatient department of obstetrics and gynecology with chief complaints of pain in the right side of the abdomen for four hours (presentation similar to that of appendicitis).
View Article and Find Full Text PDFBMC Med Imaging
August 2024
Department of Obstetrics and Gynecology, The Second Hospital of Shanxi Medical University, No. 382, Wuyi Road, Xinghualing District, Taiyuan City, 030001, Shanxi Province, China.
Uterine fibroids are common benign tumors originating from the uterus's smooth muscle layer, often leading to symptoms such as pelvic pain, and reproductive issues. Early detection is crucial to prevent complications such as infertility or the need for invasive treatments like hysterectomy. One of the main challenges in diagnosing uterine fibroids is the lack of specific symptoms, which can mimic other gynecological conditions.
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