2,603 results match your criteria: "Use of Cardiac Markers in the Emergency Department"

Background: Oxygen-rich breathing mixtures up to 100% are used in some underwater diving operations for several reasons. Breathing elevated oxygen partial pressures (PO) increases the risk of developing central nervous system oxygen toxicity (CNS-OT) which could impair performance or result in a seizure and subsequent drowning. We aimed to study the dynamics of the electrodermal activity (EDA) and heart rate (HR) while breathing elevated PO in the hyperbaric environment (HBO) as a possible means to predict impending CNS-OT.

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To assess the link between systemic immune-inflammation index (SII) and risk of major adverse cardiovascular events (MACE), contrast-induced nephropathy (CIN), and overall mortality in patients with acute myocardial infarction (AMI). Electronic search of PubMed, EMBASE, Web of Science, and Scopus databases was done for observational studies with the data on the association of SII and outcomes, such as MACE, and CIN in adult (≥18 y) patients with AMI. A random-effects model was used, and the pooled effect sizes were expressed as relative risk (RR) with corresponding 95% confidence intervals (CI).

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Toward Precision in Nutrition Therapy.

Crit Care Med

December 2024

Meakins-Christie Laboratories and Translational Research in Respiratory Diseases Program, Research Institute of the McGill University Health Centre, Montreal, QC, Canda.

Precision in critical care nutrition is paramount, as it focuses nutrition interventions on those patients most likely to benefit, or those who might potentially be harmed. Critical care nutrition must therefore be tailored to individual metabolic needs as determined by factors that control the capacity for tissue homeostasis and anabolic responses. This ideally involves the accurate and timely assessment of macronutrient and micronutrient requirements, a careful evaluation of metabolic response mechanisms and the identification of circumstances that might interfere with the productive utilization of dietary substrates.

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Objectives: To investigate the effect of Danlou tablets combined with aspirin for treating phlegm and blood stasis syndrome in coronary heart disease (CHD).

Methods: This study is a retrospective study, a total of 120 patients with phlegm and blood stasis syndrome with CHD were randomly assigned to either a control group (aspirin, 100 mg, once daily) or an observation group (Danlou tablets, 1.5 g, three times daily; aspirin, 100 mg, once daily) at a 1:1 ratio.

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Association between adverse birth outcomes and long-term risk of premature cardiovascular disease and mortality in a contemporary population-based cohort of 502,383 pregnant women.

Am Heart J

December 2024

Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, T6G 2R7; Women and Children's Health Research Institute, 232 HMRC, University of Alberta, Edmonton, Alberta, T6G 2S2.

Background: Relatively few studies have examined the association between the entire spectrum of adverse birth outcomes [stillbirth, preterm birth (PTB), term births that are low birth weight (LBW) or high birth weight (HBW)] and long-term risk of CVD in the mother. Our objective was to examine the association between birth outcomes and risk of premature CVD or death in a contemporary cohort of pregnant women.

Methods: We conducted a retrospective population-based cohort study of women in Alberta, Canada, between 01/01/2005 and 01/01/2023.

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Extranodal marginal zone lymphoma (EMZL) is a rare subtype of non-Hodgkin's lymphoma characterized by the malignant transformation of lymphoid tissue at sites affected by chronic inflammation. Pleural marginal zone lymphoma (PMZL) is an infrequent manifestation of this condition. We report a case of PMZL co-occurring with primary lung adenocarcinoma.

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Gamma-glutamyl transferase to high-density lipoprotein cholesterol ratio: A valuable predictor of coronary heart disease incidence.

Nutr Metab Cardiovasc Dis

October 2024

Department of Emergency, Wuhan Fourth Hospital, No. 473 Hanzheng Street, Qiaokou District, Wuhan, Hubei, 430033, China.

Background And Aim: Existing studies have found that serological markers for predicting coronary heart disease (CHD) have relatively low predictive value for the severity of coronary arteries and the types of CHD. GGT to HDL-C ratio (GHR) has been shown to be associated with T2DM and non-alcoholic fatty liver disease. Therefore, we explore the relationship among GHR, CHD and its subgroups.

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Article Synopsis
  • Smoking significantly increases resistin concentrations in perivascular adipose tissue (PVAT) among coronary artery disease (CAD) patients, with ever-smokers showing notably higher levels than never-smokers.
  • The study involved 110 CAD patients scheduled for coronary artery bypass grafting (CABG), categorized by smoking status (never, current, and past smokers), with resistin and inflammatory markers measured.
  • Findings indicate a strong correlation between smoking history (pack-years), plasma resistin, and inflammatory markers (IL-6, hs-CRP), highlighting the negative impact of smoking on endothelial function and fat tissue biology in CAD patients.
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Article Synopsis
  • The study investigates how T follicular helper cells and the cytokine IL-21 contribute to hypoxia-induced pulmonary hypertension (HPH), a condition that can lead to serious heart problems.
  • Using mouse models, the research found that mice lacking IL-21 or with reduced T cells showed less severe pulmonary hypertension, suggesting that IL-21 plays a crucial role in the disease's progression.
  • The findings revealed that chronic exposure to hypoxia increases germinal center B cell activity and promotes a shift in macrophages towards a phenotype that exacerbates vascular remodeling, showcasing potential targets for future therapies.
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Purpose: Reducing renal ischemia is crucial for the function and survival of grafts from nonheartbeat donors, as it leads to inflammatory responses and tubulointerstitial damage. The primary concern with organs from nonheartbeat donors is the long warm ischemia period and reperfusion injury following renal transplantation. This study had two main goals; one goal is to determine how Necrostatin-1 targeting the PANoptosome affects PANoptosis in the nonheart-beating donor rat model.

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Article Synopsis
  • About 70% of bladder cancer cases are non-muscle invasive (NMIBC) and inflammation, influenced by factors like smoking, affects treatment outcomes with BCG therapy.
  • A study analyzed data from 1,313 NMIBC patients to examine how smoking and systemic inflammation impact the effectiveness of BCG using a machine-learning algorithm.
  • The results indicated that both smoking status and specific inflammatory markers can significantly predict the risk of disease progression, highlighting the need for tailored treatment strategies and further research to confirm the findings.
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Article Synopsis
  • Malondialdehyde (MDA) is identified as a potential predictor of inhospital mortality in patients with acute coronary syndrome (ACS), a condition with limited research on this marker compared to stable angina pectoris.
  • The study involved 556 ACS patients, using leftover plasma samples to analyze various blood markers, including MDA, troponin, and others, in relation to inhospital mortality.
  • Results showed that MDA levels, along with age and creatine, were independent predictors of inhospital mortality, with an optimal MDA cutoff value of >33.1 providing high sensitivity (85%) and specificity (88.17%) for predicting outcomes.
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Circulating RBP4 and FABP4 concentrations in patients with chronic schizophrenia are associated with increased epicardial adipose tissue volume and metabolic syndrome.

Eur Arch Psychiatry Clin Neurosci

November 2024

Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Yuli Branch, No. 91, Xinxing St., Yuli Township, Hualien, 981002, Taiwan.

Schizophrenia has been linked to an elevated cardiovascular risk profile and premature onset of cardiovascular disease. Quantifying epicardial adipose tissue (EAT) volume provides insight into its correlation with coronary artery disease (CAD) severity and associated risk factors. Previous research indicates higher pericardial adipose tissue in individuals with schizophrenia compared to non-schizophrenic counterparts.

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PiCCO or Cardiac Ultrasound? Which Is Better for Hemodynamic Monitoring in ICU?

Medicina (Kaunas)

November 2024

Department of Cardiology, Emergency County Hospital of Craiova, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.

Advanced hemodynamic monitoring is fundamental in the management of the critically ill. Blood pressure and cardiac function are key markers of cardiovascular system function;, thus, having accurate measurements of these parameters in critically ill patients is essential. Currently, there are various methods available to choose from, as well as a greater understanding of the methods and criteria to be able to compare devices and select the best option for our patients' needs.

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Aims: Mineralocorticoid receptor antagonists (MRA) improve outcomes in heart failure with reduced ejection fraction (HFrEF) but are underused. Point prevalent use has been described, but the kinetics of discontinuation and the extent of reinitiation have not been studied.

Methods And Results: Patients with HFrEF enrolled in the Swedish Heart Failure Registry between 2006 and 2021 were linked to the Prescribed Drug Register.

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Time-dependent association of grey-white ratio on early brain CT predicting outcomes after cardiac arrest at hospital discharge.

Resuscitation

November 2024

Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

Article Synopsis
  • Cerebral edema after cardiac arrest can be assessed using the grey matter to white matter radiodensity (GWR) ratio from CT scans, with severe edema linked to worse patient outcomes.
  • A study examined 2,204 patients who were unresponsive after cardiac arrest, analyzing how the GWR's ability to predict in-hospital mortality and death by neurologic criteria (DNC) changed in the first 24 hours following the event.
  • Results indicated that the sensitivity of GWR for predicting mortality improved over the first five hours post-arrest, while maintaining a low false positive rate, suggesting that timing of GWR assessments is critical for accurate prognostication.
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The diagnostic value investigation of programmed cell death genes in heart failure.

BMC Cardiovasc Disord

November 2024

Department of Emergency, Jiangnan University Medical Center, JUMC, No.68 Zhongshan Road, Wuxi, Jiangsu Province, 214002, China.

Article Synopsis
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The impact of ulinastatin on lymphocyte apoptosis and autophagy in sepsis patients.

Sci Rep

November 2024

Emergency Department, The Second Affiliated Hospital of Harbin Medical University, No.246 Xuefu Road, Nangang District, Harbin, 150001, Heilongjiang Province, China.

Article Synopsis
  • * 40 sepsis patients were divided into two groups: one receiving UTI with standard treatment and the other receiving only standard treatment; blood samples were analyzed for various health markers.
  • * Results indicated that UTI significantly reduced lymphocyte apoptosis, enhanced autophagy, lowered inflammatory markers, and improved liver, kidney, and heart function in the treated patients.
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