5 results match your criteria: "Urumqi General Hospital of Lanzhou Military Command of PLA[Affiliation]"
Clinical potential of miRNA-221 as a novel prognostic biomarker for hepatocellular carcinoma.
Cancer Biomark
March 2017
Department of Internal Medicine, Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Article Synopsis
- miRNA-221 is a type of tiny molecule that has been found in many tumors, which might mean it helps cancer grow.
- Researchers studied how miRNA-221 appears in liver cancer (HCC) and found it is higher in cancer tissues than in normal nearby tissues.
- Patients with more miRNA-221 in their tumors tend to have worse outcomes and shorter survival times, making it an important marker to help predict how patients will do.
Interaction of KLF6 and Sp1 regulates basigin-2 expression mediated proliferation, invasion and metastasis in hepatocellular carcinoma.
Oncotarget
May 2016
Department of Oncology, Urumqi General Hospital of Lanzhou Military Command of PLA, Urumqi, 830000, P. R. China.
Accumulating evidence suggests that the tumor suppressor gene Krüppel-like factor 6 (KLF6) plays important roles in both development and progression of cancer. However, the role of KLF6 in hepatocellular carcinoma (HCC) remains unclear. Cancer-related molecule basigin-2 plays an important role in HCC progression and metastasis.
View Article and Find Full Text PDFBasigin-2 upregulated by receptor activator of NF-κB ligand enhances lung cancer-induced osteolytic lesions.
Cancer Cell Int
April 2016
Department of Oncology, Tangdu Hospital, Cancer Institute, Fourth Military Medical University, Xi'an, 710038 People's Republic of China.
Background: Lung cancer bone metastasis causes poor prognosis. Basigin-2, a novel cancer-associated biomarker, is upregulated in lung cancer and has been linked with tumor progression. But little is known about the role of basigin-2 in lung cancer bone metastasis and osteolytic lesion.
View Article and Find Full Text PDFCD147 overexpression promotes tumorigenicity in Chinese hamster ovary cells.
Cell Biol Int
April 2016
State Key Laboratory of Cancer Biology, Department of Cell Biology, Cell Engineering Research Center, Fourth Military Medical University, Xi'an, 710032, China.
CD147 overexpresses in many epithelium-originated tumors and plays an important role in tumor migration and invasion. Most studies aim at the role of CD147 in tumor progression using tumor cell models. However, the influence of abnormal overexpression of CD147 on neoplastic transformation of normal cells is unknown.
View Article and Find Full Text PDFA regulatory loop involving miR-22, Sp1, and c-Myc modulates CD147 expression in breast cancer invasion and metastasis.
Cancer Res
July 2014
Authors' Affiliations: Cell Engineering Research Center and Department of Cell Biology, Fourth Military Medical University, Xi'an;
Breast cancer is the most common cancer in women for which the metastatic process is still poorly understood. CD147 is upregulated in breast cancer and has been associated with tumor progression, but little is known about its regulatory mechanisms. In this study, we demonstrated that CD147 was overexpressed in breast cancer tissues and cell lines, and the high expression correlated with tumor invasion and metastasis.
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