630 results match your criteria: "Urticaria Pressure"
Occupational anaphylaxis: A Position Paper of the German Society of Allergology and Clinical Immunology (DGAKI).
Allergol Select
November 2024
Department of Dermatology and Allergy Biederstein, School of Medicine and Health, Technical University of Munich TUM).
Background: Anaphylaxis is a systemic allergic reaction that is potentially life-threatening. Occupational anaphylaxis is an anaphylaxis that occurs in an occupational context. In this position paper, we propose diagnostic criteria for occupational anaphylaxis and provide an overview of the current state of knowledge in terms of prevalence, triggers, prevention, and management.
View Article and Find Full Text PDFReducing diltiazem-related hypotension in atrial fibrillation: Role of pretreatment intravenous calcium.
Am J Emerg Med
November 2024
University of Health Sciences, Haseki Training and Research Hospital, Department of Emergency Medicine, Istanbul, Türkiye.
Article Synopsis
- This study investigated if intravenous calcium pretreatment can help prevent hypotension caused by diltiazem in adults with atrial fibrillation or flutter and fast heart rates.
- A total of 217 patients participated, being assigned to either a placebo group or groups receiving different doses of IV calcium before treatment with diltiazem.
- Results showed that calcium pretreatment was effective in preventing hypotension without reducing the effectiveness of diltiazem in controlling heart rates, and no significant side effects were noted between groups.
Key differences between chronic inducible and spontaneous urticaria.
Front Allergy
October 2024
Division of Allergy, University Clinic of Respiratory and Allergic Diseases Golnik, Golnik, Slovenia.
Introduction: The latest international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for urticaria recommends limited laboratory testing for chronic spontaneous urticaria (CSU) and selective testing for only certain chronic inducible urticaria (CIndU) subtypes, though the rationale for these recommendations is poorly explained. This study aimed to improve the understanding of CIndU subtypes by comprehensively comparing their demographic, clinical, and laboratory characteristics with those of the better-characterized CSU.
Methods: We conducted a retrospective analysis of 567 patients (median age 41 years, 67% female) diagnosed with CSU, symptomatic dermographism (SD), cold urticaria (ColdU), cholinergic urticaria (CholU), and delayed pressure urticaria (DPU).
High Efficacy of Dupilumab in Omalizumab-Refractory Severe Chronic Spontaneous Urticaria and Delayed Pressure Urticaria.
Actas Dermosifiliogr
October 2024
Universidad de Castilla La Mancha, Albacete, España; Servicio de Dermatología, Complejo Hospitalario Universitario de Toledo, Toledo, España.
Angry back.
Skin Health Dis
October 2024
Department of Dermatology Leiden University Medical Center Leiden Netherlands.
Article Synopsis
- - A 16-year-old boy developed a painful rash on his back after landing flat on it while performing acrobatics in a swimming pool.
- - The rash appeared minutes after the incident and was accompanied by discomfort in the affected area.
- - He was diagnosed with pressure urticaria, a condition that causes skin reactions in response to pressure on the skin.
A Sting in the Tale: Spurious Erythrocytosis Following Bee Stings Mimicking Gaisböck's Syndrome.
Cureus
August 2024
Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Article Synopsis
- Bee stings can be dangerous and sometimes lead to serious reactions like angioedema, which is swelling caused by bee venom.
- Getting stung multiple times can cause conditions like toxic shock syndrome, while a single sting can lead to rashes or even anaphylaxis, which is a severe allergic reaction.
- The report also mentions a man who got stung by bees and developed a rare condition called Gaisböck's syndrome, but he got treated and felt better afterward.
Potential anaphylactoid reaction to nicardipine.
J Am Coll Emerg Physicians Open
August 2024
Department of Pharmacy St. Elizabeth Hospital Youngstown Ohio USA.
Article Synopsis
- Anaphylactic and anaphylactoid reactions are serious allergic responses that require immediate treatment, presenting symptoms like bronchospasm, urticaria, and potentially fatal cardiovascular issues.
- The case involves a 52-year-old male with an acute left thalamic hemorrhage and dangerously high blood pressure, initially treated with hydralazine, which proved ineffective.
- While increasing the dose of nicardipine for better blood pressure control, the patient experienced severe side effects including swelling, urticaria, tachycardia, wheezing, and low oxygen saturation, indicating a serious reaction to the medication.
A Case Report of Dermatographia.
J Educ Teach Emerg Med
July 2024
Warren Alpert Medical School of Brown University, Providence, RI.
Article Synopsis
- The text discusses a case of symptomatic dermatographia, a condition where light scratching causes raised welts on the skin.
- Dermatographia is categorized as an inducible urticaria that can be visually alarming for patients but is harmless in nature.
- The main focus is on providing reassurance to patients experiencing this condition, despite its distressing appearance.
Acute urticaria and cardiovascular diseases.
Am J Med Sci
August 2024
Leumit Health Services, Tel Aviv-Yafo 6473817, Israel; Department of Family Medicine, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv-Yafo 6997801.
Article Synopsis
- The study explores the link between acute urticaria (AU) and cardiovascular conditions, aiming to identify common comorbidities among AU patients compared to a control group.
- Results showed higher levels of various health indicators (like blood pressure and BMI) in AU patients and significant associations with several cardiovascular issues, including heart diseases and arrhythmias.
- The findings highlight the need for medical professionals to be aware of cardiovascular risks in AU patients, suggesting that these conditions might share underlying mechanisms, warranting further investigation.
[Rapid determination of nine preservatives in tobacco flavor by three phase-hollow fiber-liquid phase microextraction-high performance liquid chromatography].
Se Pu
August 2024
Quality Inspection and Test Station, Shanghai Tobacco Group Co. Ltd., Shanghai 200082, China.
Article Synopsis
- Tobacco flavors in various products often contain preservatives like benzoic acid and sorbic acid to prevent fungal growth, but excessive consumption of these can be harmful to health.
- Accurate measurement of these preservatives is vital for safety, as they can lead to adverse reactions in sensitive individuals and some, like parabens, disrupt endocrine functions.
- A new method using three phase-hollow fiber-liquid phase microextraction combined with high performance liquid chromatography has been developed to effectively analyze nine key preservatives in tobacco flavors, addressing challenges in sensitivity and operational costs of previous methods.
New insights into chronic inducible urticaria.
Curr Allergy Asthma Rep
August 2024
Institute of Allergology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, and Berlin Institute of Health, 10178, Berlin, Germany.
Article Synopsis
- Chronic inducible urticaria (CIndU) is a difficult-to-manage condition marked by recurring hives and swelling, triggered by specific factors, and recent research has focused on understanding its causes and improving treatment options.
- New methods for evaluating patient experiences have been developed, highlighting the significant impact CIndU has on quality of life and enabling better diagnosis through provocation tests for different subtypes.
- Currently, second-generation non-sedating antihistamines are the primary recommended treatment, but they often fall short; however, off-label use of omalizumab shows promise, along with other emerging therapies being researched for future options.
Chronic urticaria: unmet needs, emerging drugs, and new perspectives on personalised treatment.
Lancet
July 2024
Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; Fraunhofer Institute for Translational Medicine and Pharmacology, Immunology and Allergology, Berlin, Germany.
Article Synopsis
- * Current treatment guidelines suggest increasing doses of second-generation antihistamines, but many patients don't see improvement due to various underlying causes.
- * New research is shifting toward personalized treatments based on individual patient factors, with promising developments like targeted therapies and medications that may effectively modify the disease.
Chronic Inducible Urticaria.
Immunol Allergy Clin North Am
August 2024
Department of Dermatology and Venerology, Kepler University Hospital, Urticaria Center of Excellence and Reference (UCARE), Linz, Austria; Center for medical research, Johannes Kepler University, Linz, Austria; Institute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany. Electronic address:
Article Synopsis
- * Diagnosis relies on patient history, trigger tests, and self-reported symptoms.
- * Current treatments mirror those for chronic spontaneous urticaria but are largely off-label; new targeted therapies are in clinical trials due to the significant impact on patients.
Delayed Pressure Urticaria Associated With Altitude Chamber Training Responsive to Cyclosporine and Omalizumab.
Mil Med
November 2024
Allergy and Immunology Fellowship Program, San Antonio Uniformed Services Health Education Consortium, Wilford Hall Ambulatory Surgical Center, Lackland AFB, TX 78236, USA.
Article Synopsis
- Delayed pressure urticaria (DPU) is a type of chronic urticaria that causes skin reactions like wheals 30 minutes to 24 hours after pressure is applied.
- A military flight crew member developed DPU after rapid decompression during altitude training, presenting symptoms like swelling and erythematous plaques.
- His condition did not respond to standard antihistamine treatment but improved significantly with a combination therapy and ultimately with omalizumab, allowing him to return to active duty.
Unveiling therapeutic frontiers: DON/DRP-104 as innovative Plasma kallikrein inhibitors against carcinoma-associated hereditary angioedema shocks - a comprehensive molecular dynamics exploration.
Cell Biochem Biophys
June 2024
Molecular Bio-Computation and Drug Design Research Group, School of Health Sciences, University of KwaZulu Natal, Westville Campus, Durban, 4001, South Africa.
Article Synopsis
- - Human plasma kallikrein (PKa) is crucial in regulating inflammation and blood processes, and dysregulation is linked to Hereditary Angioedema (HAE), which can occur alongside cancers.
- - There's a need for treatments that target both HAE and cancer, leading to the investigation of a prodrug (DRP-104) and its active form (DON) as potential PKa inhibitors with anti-cancer properties.
- - The study found that DON and DRP-104 showed promising binding characteristics and stability when compared to existing HAE treatments, highlighting their potential for clinical development.
Radiocontrast Medium-Induced Kounis Syndrome in a Dialysis Patient: A Case Report.
Cureus
May 2024
Emergency and Critical Care Medicine, Komaki City Hospital, Komaki, JPN.
Article Synopsis
- * After experiencing respiratory distress and chest pain shortly after the radiocontrast medium was administered, the patient showed signs of cardiac ischemia based on ECG and echocardiogram results, leading to the Kounis syndrome diagnosis.
- * Following an adrenaline injection that stabilized his condition, he was monitored without immediate coronary angiography, emphasizing the need for careful evaluation before such interventions in patients with similar radiocontrast-related reactions.
Tezepelumab improved chronic rhinosinusitis with nasal polyps in a Patient with aspirin exacerbated respiratory disease.
Respir Med Case Rep
May 2024
Department of Respirology, National Hospital Organization Yokohama Medical Center, 3-60-2 Harajuku, Totsuka-ku, Yokohama, 245-8575, Japan.
Article Synopsis
- * A 74-year-old Japanese woman with a long history of sinus issues and asthma developed AERD after an adverse reaction to NSAIDs, leading to a diagnosis of severe eosinophilic CRSwNP.
- * Switching her treatment from benralizumab to tezepelumab resulted in significant improvements in her asthma symptoms, nasal congestion, and olfactory dysfunction, indicating the importance of tailored therapies for CRSwNP and AERD.
Mast cell degranulation and bradykinin-induced angioedema - searching for the missing link.
Front Immunol
May 2024
Department of Immunology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
Article Synopsis
- Initiation of the bradykinin cascade can cause angioedema attacks without wheals, particularly in hereditary angioedema due to C1 inhibitor deficiency (HAE-C1-INH), highlighting a complex interplay between mast cells and this process.
- * Recent findings suggest mast cell degranulation might activate the kallikrein-kinin system, leading to bradykinin formation, while also revealing a connection between bradykinin and histamine symptoms, despite their distinct clinical presentations.
- * Exploring mast cell-related receptors, specifically MRGPRX2, and their ligands could help understand individual variability in HAE-C1-INH responses, raising important questions about potential therapeutic interventions targeting mast cell activation versus br
Acute quadruple extremity compartment syndrome due to angio-oedema after polypharmacy overdose including olmesartan medoxomil, telmisartan and vildagliptin.
BMJ Case Rep
April 2024
Department of Intensive Care Medicine, Kameda Medical Center, Kamogawa, Japan.
Article Synopsis
- - A middle-aged woman developed acute compartment syndrome (ACS) in all four extremities after overdosing on multiple medications, including nifedipine and olmesartan, which led to severe swelling and skin necrosis.
- - Her condition required emergency intubation due to haemodynamic instability, and despite initial stabilization, escalating limb swelling was noted, with compartment pressures exceeding 30 mm Hg.
- - The case suggests that the ACS was likely triggered by drug-induced angio-oedema from the medications, highlighting the need for careful monitoring for ACS in patients experiencing significant limb swelling after such overdoses.
Association Between Early Patient Characteristics and IgE-Mediated Allergy in the Perioperative Setting.
J Allergy Clin Immunol Pract
May 2024
Department of Anesthesiology and Intensive Care, Assistance Publique-Hôpitaux de Paris, University Hospitals Paris Seine-Saint-Denis and Sorbonne Paris Nord University, Bobigny, France.
Article Synopsis
- Early recognition of perioperative anaphylaxis is vital but challenging due to varying clinical presentations; IgE-mediated allergy can be life-threatening.
- A study analyzed 145 adults with suspected hypersensitivity, revealing that a specific cutaneous vasoconstriction phenotype shortly after drug exposure was strongly linked to IgE-mediated allergy.
- Associated factors included low end-tidal carbon dioxide and low mean arterial pressure, with delayed vasodilation further supporting the allergy diagnosis; a model using these characteristics showed promising accuracy in identifying allergic reactions.
[Standard technical specifications for methacholine chloride (Methacholine) bronchial challenge test (2023)].
Zhonghua Jie He He Hu Xi Za Zhi
February 2024
Article Synopsis
- The methacholine challenge test (MCT) is a key method for assessing airway hyperresponsiveness, particularly for diagnosing and treating bronchial asthma.
- A consensus group of experts in respiratory health has updated guidelines on MCT usage, focusing on common clinical issues, preparation, safety, and result interpretation.
- The updated guidelines specify who should undergo the MCT, outline absolute contraindications, and aim to assist healthcare practitioners in effectively using the test for patient assessment and treatment decisions.
Effects of Two Different Cold Application Methods After Rhinoplasty: A Randomized Clinical Trial.
Plast Aesthet Nurs (Phila)
January 2024
Arzu Ilce, PhD, is a Professor at Bolu Abant İzzet Baysal University, Faculty of Health, Department of Surgical Nursing, Bolu, Turkey.
Article Synopsis
- * Patients were randomly assigned to either the ice group or the gel mask group, with no significant differences in baseline characteristics between the two.
- * Results indicated that the cooling gel eye mask group experienced less pain and edema and reported better comfort, suggesting it is a more effective option for recovery after rhinoplasty.
Relevant adverse events and drug discontinuation of sacubitril/valsartan in a real-world Japanese cohort: REVIEW-HF registry.
J Cardiol
August 2024
Department of Medical and Health Information Management, National Cerebral and Cardiovascular Center, Osaka, Japan; Department of Cardiovascular Medicine, Nara Medical University, Nara, Japan.
Article Synopsis
- A multicenter study in Japan assessed the safety and outcomes of patients with heart failure prescribed sacubitril/valsartan, revealing that many patients treated are not typically included in clinical trials.
- Among 993 patients, significant adverse events (AEs) were noted in 22.5% within three months, with hypotension being the most common reason for discontinuation of the medication.
- High-risk factors for experiencing AEs were identified, including worse heart failure symptoms and lower blood pressure or kidney function, highlighting the need for careful monitoring by healthcare providers.
Sanya climatic-treatment cohort profile: objectives, design, and baseline characteristics.
Front Public Health
November 2023
Department of Science and Education, Hainan Branch, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Sanya, China.
Article Synopsis
- The study investigates the effects of tropical climates on allergic diseases among elderly individuals who migrate from northern China to Sanya City, Hainan Province, for the winter.
- A total of 756 participants, averaging 66.1 years old, were assessed for various allergic conditions, with results indicating significant symptom relief while living in the tropical environment.
- Preliminary findings suggest that the warmer climate may improve conditions such as allergic rhinitis, asthma, and COPD in these migratory-bird old people.
Airway Involvement and Intervention in Non-ACE-Inhibitor-Induced Angioedema.
Laryngoscope
May 2024
Department of Otolaryngology - Head and Neck Surgery, University of Rochester Medical Center, Rochester, New York, U.S.A.
Article Synopsis
- The study aims to identify the characteristics and risk factors of patients experiencing non-ACEI-induced angioedema who may need airway intervention.
- Over 4.5 years, medical records of 181 patients were analyzed, and key findings revealed that certain factors like diastolic blood pressure, symptoms of dysphonia, and specific areas of edema were significantly related to the need for airway management.
- The conclusions suggest that understanding these factors can help healthcare providers assess risk and manage care for patients with non-ACEI-induced angioedema more effectively.