7,343 results match your criteria: "Urticaria Chronic"
Commun Med (Lond)
November 2024
Division of Immunology and Allergy, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.
Postepy Dermatol Alergol
October 2024
Special Hospital for Pulmonary Diseases, Zagreb, Croatia.
Introduction: Chronic urticaria (CU) is defined as the presence of recurring hives and/or angioedema lasting more than 6 weeks. The precise impact of food allergies, particularly to galactose-α-1,3-galactose (α-gal) and omega-5-gliadin (O5G), on the development of CU is not well established.
Aim: The study examines the frequency of sensitisation to these allergens and their clinical significance in individuals with CU.
Cytokine
January 2025
Department of Allergy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Institute of Allergy and Clinical Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.. Electronic address:
Background: Omalizumab, an anti-IgE biological agent, is commonly prescribed as a second-line therapy for Chronic Spontaneous Urticaria (CSU). However, there is a lack of biomarkers to predict which CSU patients will respond favorably to omalizumab.
Objective: Our study aims to identify cytokine markers associated with the efficacy of omalizumab in treating CSU.
Allergol Select
November 2024
Institute of Allergology, Charité Universitätsmedizin Berlin und Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin.
Curr Opin Rheumatol
January 2025
Marmara University School of Medicine, Department of Dermatology, Istanbul, Türkiye.
Pharmaceuticals (Basel)
November 2024
Department of Pathophysiology and Transplantation, Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, 20122 Milan, Italy.
Chronic spontaneous urticaria (CSU) is a complex dermatological condition characterized by recurrent wheals and/or angioedema lasting for more than six weeks, significantly impairing patients' quality of life. According to European guidelines, the first step in treatment involves second-generation H1-antihistamines (sgAHs), which block peripheral H1 receptors to alleviate symptoms. In cases with inadequate responses, the dose of antihistamines can be increased by up to fourfold.
View Article and Find Full Text PDFJ Clin Med
November 2024
Department of Internal Diseases, Allergology, Endocrinology and Gastroenterology, Institute of Medical Sciences, University of Opole, 45-040 Opole, Poland.
Int J Mol Sci
November 2024
Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon 16499, Republic of Korea.
Eur Ann Allergy Clin Immunol
November 2024
Division of Allergy and Clinical Immunology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
There is limited data on the use of baseline IgE level as a predictor of omalizumab response in chronic urticaria (CU). The aim of the present study was to determine if baseline serum total IgE level is associated with response at six months of standard-dose omalizumab. The study was designed as a retrospective, single-center, cohort survey.
View Article and Find Full Text PDFExpert Rev Clin Immunol
December 2024
Urticaria Center of Reference and Excellence (UCARE), Institute of Allergology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
World Allergy Organ J
November 2024
Menarini Asia-Pacific Holdings Pte Ltd, Singapore.
Int Arch Allergy Immunol
November 2024
Department of Dermatology and Venereology, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Background: Immunoglobulin E (IgE) plays a pivotal role in the pathogenesis of allergic diseases by engaging with FcεRI and FcεRII receptors, triggering allergic responses. The development of anti-IgE antibodies, such as omalizumab, has introduced a targeted approach to allergy treatment by neutralizing free IgE and dampening the allergic cascade.
Summary: This review synthesizes the current understanding of IgE's role in allergic diseases and evaluates the clinical utility of omalizumab.
Actas Dermosifiliogr
November 2024
Universidad de Castilla-La-Mancha, Toledo, España; Servicio de Dermatología. Hospital Universitario de Guadalajara, Guadalajara, España; Servicio de Dermatología. Hospital Universitario Fundación Jiménez Díaz, Madrid, España; Departamento de Medicina y Especialidades Médicas. Facultad de Medicina y Ciencias de la Salud. Universidad de Alcalá, Alcalá de Henares, España. Electronic address:
Background And Objective: Diagnosis of vibratory urticaria/angioedema is established after performing the vortex provocation test. There is current consensus on measuring the forearm perimeter after running such test to define a positive response to it.
Material And Method: We evaluated the frequency of prior symptoms following vibratory stimuli in volunteers using a questionnaire, response to the vortex provocation test in the same volunteers (increase in forearm perimeter, erythema, localized edema, heat, and pruritus), interrater reliability, and correlation between the scores obtained in the questionnaire and response to the test.
Eur Ann Allergy Clin Immunol
November 2024
Department of Pathophysiology and Transplantation, Università Degli Studi di Milano, Milan, Italy.
Chronic spontaneous urticaria (CSU) response to anti-IgE treatment can be rapid, late or absent. Recently, potential mechanisms of activation of mast cells alternative to FceRI, including mas-related G protein-coupled receptor X2 (MRGPRX2), activation of coagulation cascade, and activation of eosinophils have been described. We measured several potential in-vitro markers, including well-known MRGPRX2 activators, in sera of patients CSU both responding and not responding to omalizumab.
View Article and Find Full Text PDFObjective: To assess the efficacy of combining acupuncture with pricking blood therapy to treat chronic spontaneous urticaria (CSU) and compare its outcomes with those of second-generation H1-antihistamines.
Methods: Seventy CSU patients were enrolled and randomly assigned to receive treatment with either oral loratadine tablets or a combination of acupuncture and pricking blood therapy (n=35 each). Evaluations were conducted at baseline, at the conclusion of the 4-week treatment period, and at the 4th and 8th weeks post-treatment time points.
J Allergy Clin Immunol
November 2024
Division of Allergic Diseases, Mayo Clinic, Rochester, Minn. Electronic address:
Bull Math Biol
November 2024
Department of Dermatology, Hiroshima City Hiroshima Citizens Hospital, Motomachi, Naka-ku, Hiroshima, 730-8518, Japan.
PLoS One
November 2024
Dongnam Esoo Korean Medical Clinic, Cheongju-si, Republic of Korea.
BMJ Case Rep
November 2024
Memorial University of Newfoundland Faculty of Medicine, St. John's, Canada.
Aquagenic urticaria, a rare dermatological condition characterised by urticarial eruptions following water contact, poses significant diagnostic and therapeutic challenges. This condition, although uncommon, necessitates heightened clinical awareness due to its substantial impact on the patient's quality of life. We present a comprehensive account of a paediatric case involving a girl in her mid-teens, who developed recurrent wheals post-exposure to water, independent of its temperature or source.
View Article and Find Full Text PDFCureus
October 2024
Medical Affairs, Alkem Laboratories Ltd., Mumbai, IND.
Managing pruritic conditions is essential due to their significant impact on patients' quality of life. Chronic urticaria (CU), characterized by persistent itching and hives, severely affects daily activities and sleep. CU includes chronic inducible urticaria and chronic spontaneous urticaria, with the latter lacking identifiable triggers, making treatment especially challenging.
View Article and Find Full Text PDFAm J Clin Dermatol
November 2024
Institute of Allergology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Hindenburgdamm 27, 12203, Berlin, Germany.
Thromb J
November 2024
Department of Dermatology, University of Nebraska Medical Center, 985645, Omaha, NE, 68198-5645, USA.
Radiol Case Rep
January 2025
Shanxi Key Laboratory of Brain Disease Control, Shanxi Provincial People's Hospital, Taiyuan, China.
Allergy Asthma Proc
November 2024
Chronic Skin Diseases Unit, Department of Dermatology, Urticaria Center of Reference and Excellence, Kayseri City Education and Research Hospital, University of Health Sciences, Kayseri, Turkey.
Symptomatic dermographism (SD) is the most common form of chronic inducible urticaria. SD disease activity increases with food intake in adult patients. Whether this is also so in children with SD is currently unknown.
View Article and Find Full Text PDFAllergol Immunopathol (Madr)
November 2024
Department of Internal Medicine, Faculty of Medicine. King Abdulaziz University, Jeddah, Saudi Arabia.