4,298 results match your criteria: "Urinary Tract Infections in Pregnancy"
Transitional outcomes of adults who underwent Cohen ureteroneocystostomy for the treatment of vesicoureteral reflux as children.
Urology
December 2024
İstanbul University, İstanbul Faculty of Medicine, Department of Urology, Division of Pediatric Urology, Turkey.
Objective: To analyze the transitional outcomes of children who underwent Cohen ureteroneocystostomy(UNC) due to vesicoureteral reflux(VUR).
Methods: Files of patients who underwent UNC between January 2003 and December 2013 and had>10 years of follow-up were retrospectively reviewed.Demographic and clinical data before surgery were noted.
Pivmecillinam for Uncomplicated Acute Cystitis: A Contemporary Review.
Ann Pharmacother
December 2024
Department of Pharmacy Practice, ETSU Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, USA.
Article Synopsis
- - The review highlights the efficacy and safety of pivmecillinam in treating uncomplicated acute cystitis, based on data from six randomized controlled trials showing effectiveness at doses of 200 to 400 mg taken three times daily for 3 to 7 days.
- - Higher doses (400 mg) and longer treatment durations resulted in better clinical and bacteriologic outcomes, while pivmecillinam is particularly beneficial for populations not commonly approved by the FDA, like men or pregnant women.
- - As antibiotic resistance increases, pivmecillinam offers a new, potentially effective outpatient treatment option for uncomplicated acute cystitis in the U.S., with a focus on cost and its low resistance profile in managing uropathogens. *
Obstetrical Outcomes in Women With a History of Bladder Augmentation.
Health Sci Rep
December 2024
Department of Pediatric Surgery, New Children's Hospital Helsinki University Hospital and University of Helsinki Helsinki Finland.
Article Synopsis
Determinants of premature membrane rupture among mothers receiving labor care at public hospitals in Northeast Ethiopia: an unmatched case-control study.
Sci Rep
November 2024
Department of Reproductive Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Article Synopsis
- Premature rupture of membranes (PROM) contributes to higher risks of death and health issues in newborns, making it critical to identify its influencing factors.
- * A study was conducted at three public hospitals in Northeast Ethiopia involving 353 women in labor to explore the factors associated with PROM between December 2022 and March 2023.
- * Key determinants identified included a history of cesarean sections, abortions, previous PROM, chronic cough, malnutrition, suspected sepsis, and urinary tract infections, emphasizing the importance of thorough prenatal care.
Prevalence and Antibiotic Resistance of in Women of Childbearing Age Presenting Urinary Tract Infections from Western Romania.
Life (Basel)
November 2024
Multidisciplinary Research Center of Antimicrobial Resistance, Microbiology Department, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Article Synopsis
- * In a study of 17,273 urine samples, 130 cases tested positive for GBS, with a higher prevalence among women aged 25-34 years compared to younger women.
- * Antibiotic resistance testing revealed that GBS strains were sensitive to penicillin, ampicillin, and vancomycin, but showed high resistance rates to clindamycin and tetracycline, highlighting the need for careful antibiotic management.
Multidrug-Resistant Urinary Tract Infections in Pregnant Patients and Their Association with Adverse Pregnancy Outcomes-A Retrospective Study.
J Clin Med
November 2024
Department of Mother and Child Care, "Grigore T. Popa" University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.
Article Synopsis
- Multidrug-resistant urinary tract infections (MDR UTIs) are a significant public health issue for pregnant women, prompting a study to analyze the types of bacteria involved and their resistance patterns.
- The study included 371 pregnant patients with UTIs, categorizing them based on their resistance to antibiotics into four groups, and used statistical methods to assess the impact of these infections on pregnancy outcomes.
- Key findings revealed that MDR UTIs are associated with high resistance to common antibiotics like ampicillin and increased risks of complications such as preterm birth and neonatal health issues, highlighting the need for improved treatment protocols.
Association Between Spontaneous Preterm Labor and Genitourinary Tract Infections Among Pregnant Women in a Tertiary Care Hospital in South India: A Cross-Sectional Study.
Cureus
October 2024
Community and Family Medicine, Employee's State Insurance Corporation (ESIC) Medical College and Hospital, Chennai, IND.
Article Synopsis
- Preterm labor occurs between 20 and 37 weeks of gestation and is linked to high rates of neonatal complications; urinary tract infections (UTIs) are a major risk factor for spontaneous preterm births, with studies suggesting that 40% of cases are associated with infections.
- A cross-sectional study of 144 antenatal women at Sri Ramachandra Medical College examined the relationship between spontaneous preterm labor and genitourinary tract infections by collecting urine and vaginal samples for testing, and assessing various maternal and neonatal factors.
- Results showed that 24% of participants tested positive for UTIs, mainly women aged 25-29 from lower socioeconomic backgrounds, and UTI positivity correlated with higher white blood cell counts and CR
[Asymptomatic bacteriuria in pregnant women: controversial issues and the need to achieve interdisciplinary consensus].
Urologiia
November 2024
Rostov State Medical University, Rostov-on-Don, Russia.
Article Synopsis
- The review focuses on the current understanding of asymptomatic bacteriuria (AB) in pregnant women, highlighting the controversial aspects of its causes, diagnosis, and treatment.
- It analyzes data from various medical databases to explore global perspectives on whether antibacterial treatment for AB in pregnant women is necessary and effective.
- The conclusion suggests that AB is often a normal state rather than a pathological one, indicating that traditional approaches to diagnosing and treating it are outdated and unnecessary in most cases.
Article Synopsis
- * Timely diagnosis and appropriate antibacterial therapy (ABT) are essential for preventing adverse outcomes, with treatment varying based on the severity of the UTI; severe cases may require hospitalization and intravenous medications, while milder cases can be treated with oral drugs.
- * For uncomplicated UTIs in pregnant women, effective oral ABT options include nitrofurans, fosfomycin trometamol, and third-generation cephalosporins, particularly cefixime, which is
Article Synopsis
- The study aimed to assess the obstetric outcomes and urological complications related to asymptomatic bacteriuria (AB) in pregnant women using different diagnostic criteria.
- A total of 225 pregnant women participated, categorized into five groups based on their urine culture outcomes and treatment decisions, with factors like preterm birth and preeclampsia analyzed across these groups.
- Findings indicated that preterm birth was more common in all groups with AB, while preeclampsia was particularly prevalent in certain groups, though no significant differences were noted in complications such as hypertension or amnionitis.
Screening of urinary and genital tracts of adult females for the Chlamydia-like bacterium Parachlamydia acanthamoebae.
New Microbiol
November 2024
School of Medicine, the University of Jordan, Amman, 11942 Jordan.
Article Synopsis
Molecular investigate of slim and adhesion genes of Staphylococcus saprophyticus isolated from pregnant women with asymptomatic bacteriuria in Thi-Qar governorates.
Wiad Lek
November 2024
DEPARTMENT OF PATHOLOGICAL ANALYSIS, SCIENCE COLLAGE, THI-QAR UNIVERSITY, THI-QAR, IRAQ.
Article Synopsis
- - The study aimed to analyze and compare the occurrence of biofilm formation genes and adhesion genes in both the chromosome and plasmid of *Staphylococcus saprophyticus* from pregnant women with asymptomatic bacteriuria.
- - Out of 48 randomly selected bacterial isolates, it was found that the genes for biofilm formation (ica A) and adhesion (fnb A) were fully present in the chromosome, while their occurrence was significantly lower in the plasmid, highlighting a more substantial genetic prevalence in the chromosome.
- - The findings suggest that genes ica A, fnb A, clf A, and cna A are more frequently found compared to fnb B, indicating that the plasmid may enhance the expression
Maternal illnesses during pregnancy and the risk of childhood cancer: A medical-record based analysis (UKCCS).
Int J Cancer
November 2024
Epidemiology and Cancer Statistics Group, Department of Health Sciences, University of York, York, UK.
Article Synopsis
- The study investigates the link between maternal illnesses during pregnancy and the risk of childhood cancers, utilizing detailed medical records to avoid recall bias.
- Findings indicate that maternal anaemia is significantly associated with increased odds of childhood acute myeloid leukaemia (AML) and several embryonal tumours, suggesting a need for further investigation into nutritional deficiencies.
- Other potential associations were noted for urinary tract infections (UTIs) and preeclampsia with non-Hodgkin lymphoma, but these findings are less conclusive and require caution due to limited data.
Determinants of preterm prelabor rupture of fetal membrane among pregnant women in Ethiopia: A systematic review and meta-analysis.
PLoS One
November 2024
Department of Public Health, College of Medicine and Health Science, Debre Markos University, Debre Markos, Ethiopia.
Article Synopsis
- - Ethiopia faces high neonatal and maternal mortality rates, largely influenced by preterm prelabor rupture of membrane (PPROM), yet there's limited research on its prevalence and causes in the country
- - A systematic review gathered data from 13 studies involving 24,386 participants, finding a pooled prevalence of 6.58% for PPROM and identifying significant risk factors like urinary tract infections, abnormal vaginal discharge, and malnutrition
- - The findings highlight the urgent need for improved maternal health strategies in Ethiopia, given the strong links between PPROM and various health issues affecting pregnant women
Prevalence of urinary tract infections in pregnancy in rural Andean communities of Peru.
Womens Health (Lond)
November 2024
Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
Article Synopsis
- Urinary tract infections (UTIs) are common during pregnancy and can negatively impact health, but their prevalence in rural communities like San Marcos, Peru is not well understood.
- A study involving 250 pregnant women revealed a UTI prevalence of 27.6%, higher than other areas in Peru, despite 96% of women accessing antenatal care services.
- The results indicate that while there are no significant risk factors linked to UTIs in this population, routine UTI screenings during antenatal visits are essential to improving maternal health outcomes.
Article Synopsis
- Urinary tract infections (UTIs) are notably more frequent in pregnant women due to hormonal changes, and if untreated, can lead to complications for both mother and fetus.
- In a study of 400 patients, UTIs were identified in 26.75% of cases, with the most common bacterial uropathogens being identified and assessed for antibiotic resistance.
- The results showed high susceptibility to carbapenems among gram-negative organisms and highlighted concerns about resistance to other antibiotics, particularly among staphylococci and non-albicans yeast species.
Intrapartum antibiotic exposure and infectious diseases in childhood - a population-based cohort study.
EBioMedicine
November 2024
Research Unit of Clinical Medicine and Medical Research Centre Oulu, University of Oulu, Oulu, Finland; Department of Paediatrics and Adolescent Medicine, Oulu University Hospital, Oulu, Finland; Biocenter Oulu, University of Oulu, Oulu, Finland.
Article Synopsis
- Intrapartum antibiotics may increase the risk of infectious diseases in children, as shown in a study of nearly 10,000 children born in Northern Finland between 2007-2018.
- The research found that exposure to these antibiotics led to a higher number of infections during the first few years of life, particularly urinary tract infections.
- The study suggests that the impact of intrapartum antibiotics on childhood infections is influenced by the types of bacteria involved and their resistance to penicillin.
Pandemic-induced healthcare shifts: an observational analysis of maternal and neonatal outcomes in adolescent pregnancies.
Front Med (Lausanne)
October 2024
Departamento de Inmunobioquímica, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Ciudad de Mexico, Mexico.
Article Synopsis
- The COVID-19 pandemic significantly impacted healthcare delivery for pregnant adolescents, affecting their maternal and neonatal outcomes due to challenges like isolation and restricted access to care.
- A study of 340 adolescent patients revealed that during the pandemic, cesarean delivery rates and cervicovaginitis caused by Ureaplasma spp. increased, while pre-pandemic patients exhibited higher rates of substance use and urinary tract infections.
- Overall, the findings indicate that healthcare system changes during the pandemic led to differing health outcomes, emphasizing the need for focused care for this vulnerable group during public health crises.
Asymptomatic bacteriuria screening for developing countries using a modified water quality test kit.
Appl Environ Microbiol
November 2024
Department of Microbiology and Immunology, University of South Alabama, Frederick P. Whiddon College of Medicine, Mobile, Alabama, USA.
Article Synopsis
- - Between 2% and 15% of pregnant women have asymptomatic bacteriuria (ASB), which can lead to serious pregnancy complications like pyelonephritis and low-birth weight infants, but routine screening is often missing in developing countries.
- - The Aquagenx water quality test kits, typically used for water testing, have been adapted to detect ASB in urine, showing high accuracy in clinical samples and minimal false positive and negative rates.
- - This innovative ASB screening protocol using Aquagenx not only has the potential to improve healthcare in low-resource settings but could also effectively diagnose the majority of ASB cases, as it covers 90.1% of the common causative agents.
Urogenital colonization and pathogenicity of E. Coli in the vaginal microbiota during pregnancy.
Sci Rep
October 2024
Department of Computational Biology, Institut Pasteur, Université Paris Cité, 75015, Paris, France.
Article Synopsis
- The study investigates the impact of vaginal microbiota (VM) on asymptomatic bacteriuria (ASB) in 1,553 pregnant women, highlighting the dominance of E. coli as a common cause of bacteriuria and newborn infections.
- Results indicate that a healthy VM, usually rich in Lactobacillus species, is disturbed during bacteriuria, leading to an increase in harmful gut-associated bacteria, particularly E. coli.
- Molecular analysis of E. coli genomes reveals the presence of extraintestinal pathogenic strains, suggesting that reduced Lactobacillus abundance may enable opportunistic pathogens to thrive, thereby compromising women's health during pregnancy.
Urinary tract infection among pregnant Jordanian women: role of hygiene and sexual practices.
BMC Pregnancy Childbirth
October 2024
Nursing Faculty, Liberty University, Lynchburg, VA, USA.
Article Synopsis
- - The study aimed to explore how hygiene and sexual practices relate to urinary tract infections (UTIs) in Jordanian pregnant women, involving 200 married participants aged 18-45.
- - Significant links were identified between UTI incidence and factors such as the husbands' educational levels, women's previous UTI history, and being in the second trimester of pregnancy, along with hygiene and sexual behaviors.
- - The findings suggest that improving hygiene and sexual practices, along with addressing past UTI experiences, could enhance health outcomes and reduce healthcare costs for pregnant women in Jordan.
Implementation of an algorithm for testing, diagnosis, and antibiotic stewardship of asymptomatic bacteriuria in pregnancy.
Am J Obstet Gynecol MFM
November 2024
Department of Clinical Laboratory Sciences, The University of Texas Medical Branch, Galveston, TX (Bergbower and Rajendran). Electronic address:
Article Synopsis
- - Asymptomatic bacteriuria affects a notable percentage of pregnant women, with some developing symptomatic urinary tract infections (UTIs) that carry risks like low birthweight and preterm delivery.
- - Current methods for detecting UTIs, including urine cultures and dipstick tests, have limitations, particularly in interpreting results for asymptomatic bacteriuria, highlighting the need for more reliable diagnostic guidelines.
- - The study aims to create and assess an evidence-based algorithm to improve the interpretation of urinalysis results and treatment decisions for asymptomatic bacteriuria among pregnant patients during routine obstetric visits.
Safety and efficacy of praziquantel in pregnant women infected with Schistosoma haematobium in Lambaréné, Gabon - Clinical results from the randomized, single-blinded, controlled freeBILy-Gabon trial.
Int J Infect Dis
December 2024
Centre de Recherches Médicales de Lambaréné (CERMEL), B.P. 242 Lambaréné, Gabon; Institut für Tropenmedizin, Universität Tübingen, Wilhelmstraße 27, 72074 Tübingen, Germany; Leiden University Center for Infectious Diseases (LUCID), Leiden University Medical Center (LUMC), Department of Parasitology, Albinusdreef 2, 2333 ZA Leiden, The Netherlands; Fondation pour la Recherche Scientifique (FORS), BP:88 ISBA Cotonou, Benin; German Center for Infection Research (DZIF), Partner Site Tübingen, Braunschweig, Germany.
Objectives: Despite evidence of praziquantel's (PZQ) safety for treating schistosomiasis in pregnancy, many countries withhold treatment. Only two randomized controlled trials have investigated PZQ in pregnancy, none involving Schistosoma haematobium.
Methods: Pregnant women during the second trimester in Lambaréné (Gabon) were screened for S.
Asymptomatic bacteriuria and its associated fetomaternal outcomes among pregnant women delivering at Bugando Medical Centre in Mwanza, Tanzania.
PLoS One
October 2024
Department of Microbiology and Immunology, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza, Tanzania.
Article Synopsis
- * The study examined 1,093 pregnant women at Bugando Medical Center, finding that factors like anemia and prior antenatal care are linked to higher ASB risk.
- * Women with ASB showed significantly higher rates of pre-term labor, premature rupture of membranes, and low birth weight, with E. coli being the most frequent bacteria identified.