4 results match your criteria: "Uppsala University Box 599[Affiliation]"

Article Synopsis
  • The interaction between the metabolic microbiome and humans is crucial for understanding human health and the development of diseases, with an emphasis on metabolite exchange.
  • The study aims to identify beneficial metabolites and disease modulators through targeted analysis of sulfated metabolites in plasma and urine samples.
  • Analysis of 27 individuals revealed a core sulfatome of 41 metabolites common in both plasma and urine, with age-related effects observed in 15 of these metabolites.
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An improved synthesis of Fmoc-N-methyl-alpha-amino acids.

J Org Chem

August 2005

Department of Chemistry, Organic Chemistry, Uppsala University Box 599, SE-751 24 Uppsala, Sweden.

A highly efficient and environmentally more benign synthesis of Fmoc-N-methyl-alpha-amino acids from the corresponding Fmoc-amino acid, via intermediate 5-oxazolidinones, has been developed by using Lewis acid catalysis for the reductive opening of the oxazolidinone ring.

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In this study, positively charged alkylaminosilyl monomers were used to modify the inner surface of fused silica capillaries, which subsequently were employed in capillary electrophoresis (CE) and capillary electrochromatography (CEC). The obtained surfaces yield a reversed electroosmotic flow (EOF) and have varying carbon chain lengths, that interact with the analytes and give chromatographic retention. The coating procedure is very simple and fast.

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