Reasons for the discontinuation of therapy of personal insulin pump in children with type 1 diabetes.

Introduction: Pump discontinuation is rare. It is estimated that only about 4% of patients return to multiple daily injections (MDI).

Objective: To study the factors that influence the decision to stop continuous subcutaneous insulin infusion therapy (CSII).

Usefulness of magnetic resonance findings of the hypothalamic-pituitary region in the management of short children with growth hormone deficiency: evidence from a longitudinal study.

Purpose: The purpose of this study is to assess the relationship between magnetic resonance images (MRI) of the hypothalamic-pituitary (H-P) region and response to recombinant human growth hormone (rhGH) treatment in short children with growth hormone deficiency, basing on changes of auxologic parameters, as well as to answer the question if MRI may serve for selecting and monitoring the rhGH responders.

Patients And Methods: The study group comprised 85 children treated with rhGH, aged 7.3-18.

Prospective assessment of continuous subcutaneous insulin infusion therapy in young children with type 1 diabetes.

The study assessed 3.5-year treatment with continuous subcutaneous insulin infusion (CSII) in well-controlled children with duration of type 1 diabetes mellitus longer than 1 year. Following groups were observed: the CSII group-40 children and the multiple injections (MDI) group-36 patients (age-matched, the mean of 6.