Global review reveals how disparate study motivations, analytical designs, and focal ions limit understanding of salinization effects on freshwater animals.

Global salinization of freshwaters is adversely affecting biotic communities and ecosystem processes. We reviewed six decades (1960-2020) of literature published on animal responses to increased salinities across different taxonomic and ecological contexts and identified knowledge gaps. From 585 journal articles, we characterized 5924 responses of mollusks, crustaceans, zooplankton, non-arthropod invertebrates (NAI), insects, fishes, and amphibians to salinization.

Older Adults Documenting Purpose and Meaning Through Photovoice and Narratives.

Background And Objectives: The purpose of this study was to explore how older adults perceived meaning and purpose in their lives.

Research Design And Methods: Participants (N = 15) ranged in age from 66 to 89 years, and were asked to document purpose and meaning in their lives for 15 consecutive days by using photovoice and narrative methodologies. Latent thematic analysis was used to interpret the data.

The Influence of the Motivational Climate on Rehabilitation Behaviors and Patient Satisfaction.

Context: Athletic trainers influence the motivational climate in rehabilitation, but little is known about the role of the motivational climate on patient outcomes. The purpose of this study was to investigate the influence of the motivational climate in rehabilitation on athletes' behaviors in rehabilitation (eg, effort and energy) and overall satisfaction with rehabilitation.

Design: Cross-sectional, descriptive research.

Implementing Social-Emotional Learning in the Elementary Classroom.

Social-emotional learning has the power to change how educators deliver instruction across the country. For this article, social-emotional learning research and journal articles were reviewed for the purposes of identifying common themes among existing research. Multiple perspectives were considered in the review of literature and the findings were used to identify potential issues and create overall recommendations.

Personality and compliance with COVID-19 protective measures among older Americans: Moderating effects of age, gender, and race/ethnicity.

Following the growing evidence that personality is related to various health behaviors, we examined whether personality traits were related to compliance with COVID-19 protective measures and evaluated the extent to which associations were moderated by age, gender, or race/ethnicity among older adults during a summer 2020 surge of COVID-19 cases in the United States. Data were from the 2020 Health and Retirement Study COVID-19 module. Multivariate ordinary least squares regression analyses were computed adjusting for health, psychosocial, and sociodemographic factors.

Tailoring rice varieties to consumer preferences induced by cultural and colonial heritage: Lessons from New Rice for Africa (NERICA) in The Gambia.

Rice breeding priorities in Africa often focus on agronomic gains. However, being a net importer of rice, the continent's varietal replacement success also crucially hinges on new varieties' market competitiveness vis-à-vis imports. Markets have been profoundly shaped by cultural and colonial heritage.

The Lived Experiences of African American Centenarians: Narrative Exploration From a Life Course Theory Perspective.

Background And Objectives: The purpose of this study was to examine examples of inequality experienced by African American centenarians throughout the life course.

Research Design And Methods: Data were derived from 111 oral history transcripts from the Oklahoma Oral History Project. A subsample of all centenarians who identified as African American (n = 12) was utilized.

Confronting genetic gains with markets: Retrospective lessons from New Rice for Africa (NERICA) in Uganda.

Breeders have two non-exclusive strategic investment options for increasing smallholder farmers' and consumers' livelihoods through genetic improvement of crop varieties: (i) enhancing productivity; and (ii) enhancing value and market access. New Rice for Africa (NERICA) varieties with superior agronomic characteristics were bred and introduced in various African countries in the early 2000s. Two decades later, drought tolerant NERICA4 is among the popular upland rice varieties grown across Africa.

IL-10-producing NK cells exacerbate sublethal Streptococcus pneumoniae infection in the lung.

Lung inflammation is tightly controlled to balance microbial clearance with the tissue damage that accompanies this response. Bacterial pathogens including Streptococcus pneumoniae (S. pneumoniae) modulate immune regulation by promoting secretion of the anti-inflammatory cytokine IL-10.

Feasibility of Sijunzi Tang (Chinese medicine) to enhance protein disulfide isomerase activities for reactivating malate dehydrogenase deactivated by polycyclic aromatic hydrocarbons.

The objective of this research is to investigate the enzymatic activities between protein disulfide isomerase (PDI) found in animals and plants and the properties found in a commonly used Chinese medicine called Sijunzi Tang. During the investigation, PDI, which is a monomer with a molecular mass of 57.0 kDa, was used to reactivate malate dehydrogenase (MDH).

A New Strategy to Control and Eradicate "Undruggable" Oncogenic K-RAS-Driven Pancreatic Cancer: Molecular Insights and Core Principles Learned from Developmental and Evolutionary Biology.

Oncogenic K-RAS mutations are found in virtually all pancreatic cancers, making K-RAS one of the most targeted oncoproteins for drug development in cancer therapies. Despite intense research efforts over the past three decades, oncogenic K-RAS has remained largely "undruggable". Rather than targeting an upstream component of the RAS signaling pathway (i.

Comparative assessment of soil quality parameters after implementing afforestation programme in forest areas of Hong Kong.

The objective of this research is to investigate and compare the alteration of soil parameters with and without afforestation programme in a Hong Kong forest, analysed by Principal Component Analysis (PCA). One hundred soil samples were collected from the following sites: Pak Ngau Shek (PNS), Shing Mun (SM), Tai Po Kau (TPK), Tai Tong (TT) (forest with afforestation programme) and Lantau Peak (LP) (control site). A significant difference was found in only two out of 16 parameters: pH (8.

Concept-Based Curriculum: Changing Attitudes and Overcoming Barriers.

Many nursing educators have considered the implementation of a concept-based curriculum, with active, conceptual teaching and learning strategies, which offers a way to respond to the overwhelming content saturation in many nursing curricula. However, barriers abound, including faculty concerns about loss of control, changing faculty role and identity, and fear of failure. This article clarifies these legitimate barriers and offers practical strategies for success in curriculum change.

Combined effects of land reclamation, channel dredging upon the bioavailable concentration of polycyclic aromatic hydrocarbons (PAHs) in Victoria Harbour sediment, Hong Kong.

The up-to-date concentration of polycyclic aromatic hydrocarbons (PAHs) in sediment materials of Victoria Harbour was investigated so as to evaluate the pollution potential associated with the reclamation projects in Hong Kong. A total of 100 sediment samples were collected at 20 locations. Except the control point in reservoir, the PAHs concentrations were detectable levels all sites (131-628.

Monitoring and assessment of heavy metal contamination in a constructed wetland in Shaoguan (Guangdong Province, China): bioaccumulation of Pb, Zn, Cu and Cd in aquatic and terrestrial components.

The objective of this study is to evaluate the current status of heavy metal concentrations in constructed wetland, Shaoguan (Guangdong, China). Sediments, three wetland plants (Typha latifolia, Phragmites australis, and Cyperus malaccensis), and six freshwater fish species [Carassius auratus (Goldfish), Cirrhinus molitorella (Mud carp), Ctenopharyngodon idellus (Grass carp), Cyprinus carpio (Wild common carp), Nicholsicypris normalis (Mandarin fish), Sarcocheilichthys kiangsiensis (Minnows)] in a constructed wetland in Shaoguan were collected and analyzed for their heavy metal compositions. Levels of Pb, Zn, Cu, and Cd in sediments exceeded approximately 532, 285, 11, and 66 times of the Dutch Intervention value.

Mating and memory: an educational primer for use with "epigenetic control of learning and memory in Drosophila by Tip60 HAT action".

An article by Xu et al. in the December 2014 issue of GENETICS can be used to illustrate epigenetic modification of gene expression, reverse genetic manipulation, genetic/epigenetic influence on behavioral studies, and studies using the Drosophila model organism applied to human disease. This Primer provides background information; technical explanations of genetic, biochemical, and behavioral approaches from the study; and an example of an approach for classroom use with discussion questions to aid in student comprehension of the research article.

Combining clinicopathological predictors and molecular biomarkers in the oncogenic K-RAS/Ki67/HIF-1α pathway to predict survival in resectable pancreatic cancer.

Background: The dismal prognosis of patients diagnosed with pancreatic cancer points to our limited arsenal of effective anticancer therapies. Oncogenic K-RAS hyperactivation is virtually universal in pancreatic cancer, that confers drug resistance, drives aggressive tumorigenesis and rapid metastasis. Pancreatic tumours are often marked by hypovascularity, increased hypoxia and ineffective drug delivery.

The delivery of distance education--is it time for doctoral programs in gerontology?

The delivery of higher education in gerontology is changing; students are now able to receive an education solely online. Perhaps it is time to consider offering this option at the doctoral level. A needs assessment was conducted to assess whether a doctoral program in gerontology should be created in the Great Plains Interactive Distance Education Alliance (GPIDEA) program.

A roadmap to understanding toll pathway changes: an educational primer for use with "regulation of toll signaling and inflammation by β-arrestin and the SUMO protease Ulp1".

An article by Anjum et al. in the December 2013 issue of GENETICS can be used to illustrate reverse genetic manipulation in a model organism, targeted RNA interference, synergistic gene interaction, and biochemical regulation of gene expression using post-translational modification. This Primer provides background information, technical explanations of methods and genetic approaches from the study, an example approach for classroom use, and discussion questions to promote understanding of the research article.

Review of measurement methods and clinical validation studies of noninvasive blood pressure monitors: accuracy requirements and protocol considerations for devices that require patient-specific calibration by a secondary method or device before use.

Existing standardized protocols for clinical validation of noninvasive blood pressure (BP) monitors do not have specific provisions for monitors that require patient-specific calibration by a secondary method or device before use. This article seeks to identify accuracy requirements and protocol considerations for such monitors. Measurement methods that require patient-specific calibration were reviewed to identify their clinical accuracy requirements.

History of ankle sprain as a risk factor of future lateral ankle sprain in athletes.

Despite the attention and focus lateral ankle sprains receive in athletic training practice and research, they remain the most common injury in many sports. Whereas the functional limitations and time loss from lateral ankle sprains are apparent, consistently reducing their incidence is less certain. One important step in preventing lateral ankle sprains is identifying their risk factors.

Evaluation of the Cadi ThermoSENSOR wireless skin-contact thermometer against ear and axillary temperatures in children.

The Cadi ThermoSENSOR skin-contact thermometer measures body temperature continuously and transmits readings wirelessly to a central server. This study evaluated the ThermoSENSOR against ear temperatures (ETs) measured by a Braun ThermoScan ear thermometer and axillary temperatures (ATs) measured by a Terumo digital clinical thermometer. The test participants consisted of 109 children aged 6 months to 16 years from a pediatric ward.

A study of PCR inhibition mechanisms using real time PCR.

In this project, real time polymerase chain reaction (PCR) was utilized to study the mechanism of PCR inhibition through examination of the effect of amplicon length, melting temperature, and sequence. Specifically designed primers with three different amplicon lengths and three different melting temperatures were used to target a single homozygous allele in the HUMTH01 locus. The effect on amplification efficiency for each primer pair was determined by adding different concentrations of various PCR inhibitors to the reaction mixture.