Traumatic dental injuries and related factors among sixth grade schoolchildren in four Palestinian towns.

Background: Traumatic dental injuries (TDI) are recognized as an important dental public health issue among children. The West Bank, a part of the Palestinian Authority, is in immediate neighborhood to Israel. There are inadequate epidemiologic data among the Palestinian people, on dental health issues.

Cytotoxic chemotherapy-induced odontalgia: a differential diagnosis for dental pain.

Introduction: Peripheral neurotoxicity and neuropathic pain are well-known complications of several anti-cancer chemotherapeutic agents. Such pain might cause an impairment of the patient's quality of life and is a common limiting factor of anti-cancer chemotherapy. Neurotoxicity in orofacial structures has been previously described as diffuse jaw pain or numbness.

Directly transfected langerin+ dermal dendritic cells potentiate CD8+ T cell responses following intradermal plasmid DNA immunization.

Dendritic cells (DCs) play a critical role in CD8(+) T cell priming following DNA vaccination. In contrast to other DNA injection routes or immunization with viral vectors, Ag presentation is delayed following needle injection of plasmid DNA into the skin. The contribution of various skin DC subsets to this process is not known.

[Dentinal hypersensitivity].

Dentinal hypersensitivity is defined as short and transient painful response of exposed dentin, usually cervical, to different stimuli, such as thermal, mechanical osmotic or chemical. The etiology of dentinal hypersensitivity is open tubules (because of enamel loss or gingival recession), allowing painful stimulus to reach the pulp. The hydrodynamic theory explains the mechanism through which pain is aroused.

Unsweetened ice popsicles impart a positive feeling and reduce self-mutilation after paediatric dental treatment with local anaesthesia.

Aim: The purpose of the current study was to assess whether an unsweetened ice-popsicle imparts a positive feeling to children after dental treatment in which local anaesthesia is administered, and whether it reduces the tendency of children to self-mutilate (bite the lip, cheek or tongue) after the administration of local anaesthesia.

Design: Crossover study of 31 children aged 4-11 years old who needed similar dental treatments on both sides of the mandible or maxilla under local anaesthesia. At the end of each appointment the child received a toy or an ice-popsicle especially made for this study.

The role of skin-derived dendritic cells in CD8+ T cell priming following immunization with lentivectors.

Although skin dendritic cells (DCs) have been shown to directly present Ag to CD8(+) T cells after intradermal immunization with lentivectors, the contribution of the different skin DC subsets to this process remains unclear. Using langerin-diphtheria toxin receptor transgenic mice we demonstrated that ablation of langerhans cells and langerin-expressing positive dermal DCs (Ln(+)dDCs) did not interfere with the generation of CD8(+) T cells by lentiviral vectors. Consistent with these findings, the absence of langerhans cells and Ln(+)dDCs did not hamper the presentation level of lentiviral-derived Ag by skin DCs in vitro.

Exceptional oral manifestations of amyloid light chain protein (AL) systemic amyloidosis.

Oral amyloidosis is usually presented in the tongue and is often associated with multiple myeloma. We present three patients with unusual oral manifestations of primary amyloidosis, which to the best of our knowledge have not been previously published. In two cases the oral manifestation was overt at the time of diagnosis and all cases ended in patient mortality.

Psychosocial reward of orthodontic treatment in adult patients.

The purpose of this study was to assess the short-term psychosocial impact of dental aesthetic improvement in adult subjects. Sixty-nine adult patients (61 females and 8 males, aged 21-59 years) requesting aesthetic dental improvement were prospectively and randomly recruited for the study in a private orthodontic office. A general interview included patient motivation and expectations from treatment.

Psychological distress and self-perception of oral health status among an immigrant population from Ethiopia.

Objectives: To examine the association between psychological distress (PD) and perception of oral health status among a group of Ethiopian immigrants compared to the 'gold standard' of clinical diagnosis.

Design: Three hundred and forty Ethiopian immigrants, aged 18 years or more, were interviewed using a version of the Self-Reporting Questionnaire (World Health Organization) for the assessment of psychological status and perceived dental and periodontal health status. Clinical data for dental and periodontal health status were used as the 'gold standard' against the self-perceived assessment scores among the PD and no psychological distress (NPD) groups.

IL-10 mediates resistance to adoptive transfer experimental autoimmune encephalomyelitis in MyD88(-/-) mice.

MyD88 is an adaptor molecule that functions in the innate signaling induced by proinflammatory adjuvants that interact with TLRs. Mice lacking MyD88, for example, resist active experimental autoimmune encephalomyelitis (EAE) induced by immunization with an encephalitogenic myelin oligodendrocyte glycoprotein (MOG) peptide in CFA. We reasoned that MyD88(-/-) mice, nevertheless, should be susceptible to EAE mediated by adoptive transfer of activated encephalitogenic T cell lines, which do not require adjuvant signaling for their effector functions.

Endoscopic root canal treatment.

Objective: To describe an innovative endoscopic technique for root canal treatment.

Materials And Methods: Root canal treatment was performed on 12 patients (15 teeth), using a newly developed endoscope (Sialotechnology), which combines an endoscope, irrigation, and a surgical microinstrument channel.

Results: Endoscopic root canal treatment of all 15 teeth was successful with complete resolution of all symptoms (6-month follow-up).

Saliva enables the antimicrobial activity of LL-37 in the presence of proteases of Porphyromonas gingivalis.

Proteolysis is a common microbial virulence mechanism that enables the destruction of host tissue and evasion from host defense mechanisms. Antimicrobial peptides, also known as host defense peptides, are effector molecules of the innate immunity that demonstrate a broad range of antimicrobial and immunoregulatory activities. Deficiency of the human LL-37 antimicrobial peptide was previously correlated with severe periodontal disease.

The influence of handheld mobile phones on human parotid gland secretion.

Background: Handheld mobile phones (MPHs) have become a 'cultural' accessory device, no less so than a wrist watch. Nevertheless, the use of MPHs has given rise to great concern because of possible adverse health effects from exposure to the radiofrequency radiation (RFR) emitted by the device. Previous studies suggested correlation between MPH and salivary gland tumors.

Mandibular reconstruction using stereolithographic 3-dimensional printing modeling technology.

Mandibular reconstruction can be challenging for the surgeon wishing to restore its unique geometry. Reconstruction can be achieved with titanium bone plates followed by autogenous bone grafting. Incorporation of the bone graft into the mandible provides continuity and strength required for proper esthetics and function and permitting dental implant rehabilitation at a later stage.

Trends of oral and pharyngeal cancer in Israel, by gender, age, ethnic group, and country of origin: 1970-2006.

Background: Oral and pharyngeal cancer is one of the few life-threatening oral diseases. Israel is recognized as a developed country, characterized by a heterogeneous population, a high level of sun exposure, and a large proportion of faired skinned inhabitants. The purpose of this study was to describe trends in incidence and survival rates of oral and pharyngeal cancer between 1970 and 2006.

Buccal ectopia of maxillary canines with no crowding.

Introduction: Buccally displaced canines (BDC) are usually found in crowded dentitions. Nevertheless, a small but significant number of patients with BDC have no crowding. In this study, we compared BDC dentitions with no crowding (BDC-nc), BDC dentitions with crowding (BDC-c), and uncrowded dentitions with normally erupted canines (C).