Atrioventricular re-entrant and ventricular tachycardias of left origin: a rare combination.

The simultaneous occurrence of atrial and ventricular tachycardias, or junctional and ventricular tachycardias, has been reported previously. We report on a patient presenting with syncope and demonstrating, simultaneously, atrioventricular re-entrant tachycardia and ventricular tachycardia of left origin. A left lateral concealed pathway was responsible for the former arrhythmia, while the latter arrhythmia was located in the anterolateral wall of the left ventricle.

Diabetes increases both N-ras and ets-1 expression during rat oral oncogenesis resulting in enhanced cell proliferation and metastatic potential.

Background: The expression of N-ras and ets-1 proteins was investigated in an experimental model of chemically-induced carcinogenesis in normal and diabetic (type I) Sprague-Dawley rats.

Materials And Methods: Tissue sections ranging from normal mucosa to moderately-differentiated oral squamous cell carcinoma were studied using monoclonal antibodies against N-ras and ets-1 proteins.

Results: In diabetic rats, N-ras expression increased with tumor advancement, while in normal rats N-ras was not detected in initial stages of oral oncogenesis and increased only in well-differentiated OSCC.