Effects of the hangover secret on mitigating hangover symptoms: A pilot study.

Background: Due to the popularity of excessive alcohol consumption, there is an increasing need for hangover symptom remedies. Most commercially available hangover treatment products have not been tested for efficacy through clinical study.

Aims: The purpose of this pilot study was to characterize the activity of a commercially available hangover product, The Hangover Secret (THS).

EECP improves markers of functional capacity regardless of underlying ranolazine therapy.

Objective: Enhanced external counterpulsation (EECP) and ranolazine are approved treatments for patients with chronic stable angina by the United States Food and Drug Administration (FDA). Whether EECP offers clinical benefits regardless of underlying ranolazine therapy needs further investigation.

Methods: This was a retrospective evaluation of patients referred to a specialized EECP center.

City limits: Heat tolerance is influenced by body size and hydration state in an urban ant community.

Cities are rapidly expanding, and global warming is intensified in urban environments due to the urban heat island effect. Therefore, urban animals may be particularly susceptible to warming associated with ongoing climate change. We used a comparative and manipulative approach to test three related hypotheses about the determinants of heat tolerance or critical thermal maximum ( ) in urban ants-specifically, that (a) body size, (b) hydration status, and (c) chosen microenvironments influence .

Impact of High Volume Energy Drink Consumption on Electrocardiographic and Blood Pressure Parameters: A Randomized Trial.

Background Energy drinks have been linked to an increase in emergency room visits and deaths. We aim to determine the impact of energy drinks on electrocardiographic and hemodynamic parameters in young healthy volunteers. Methods and Results A randomized, double-masked, placebo-controlled, crossover study was conducted in healthy volunteers.

The active engagement model of applied ethics as a structure for ethical reflection in the context of course-based service learning.

Purpose: The purpose of this case report is to explore the active engagement model as a tool to illuminate the ethical reflections of student physical therapists in the context of service learning in a developing country.

Methods: The study participants were a convenience sample of six students. The study design is a case report using a phenomenological perspective.

Adolescent BMI trajectories with clusters of physical activity and sedentary behaviour: an exploratory analysis.

Objective: The purpose of this study is to identify distinct body mass index (BMI) trajectories associated with weight classification, and to examine demographic characteristics and clusters of obesogenic behaviours in adolescents with these trajectories.

Methods: Data were extracted from the National Institute of Child Health and Human Development Study of Early Child Care and Youth Development ( = 1,006, Grades 5-8). The independent variables were physical activity (accelerometer and child report), sports participation, television/video watching time and recreational computer use.

Temperature and injection water source influence microbial community structure in four Alaskan North Slope hydrocarbon reservoirs.

A fundamental knowledge of microbial community structure in petroleum reservoirs can improve predictive modeling of these environments. We used hydrocarbon profiles, stable isotopes, and high-density DNA microarray analysis to characterize microbial communities in produced water from four Alaskan North Slope hydrocarbon reservoirs. Produced fluids from Schrader Bluff (24-27°C), Kuparuk (47-70°C), Sag River (80°C), and Ivishak (80-83°C) reservoirs were collected, with paired soured/non-soured wells sampled from Kuparuk and Ivishak.

The effect of α-mating factor secretion signal mutations on recombinant protein expression in Pichia pastoris.

The methylotrophic yeast, Pichia pastoris, has been genetically engineered to produce many heterologous proteins for industrial and research purposes. In order to secrete proteins for easier purification from the extracellular medium, the coding sequence of recombinant proteins is initially fused to the Saccharomyces cerevisiae α-mating factor secretion signal leader. Extensive site-directed mutagenesis of the prepro-region of the α-mating factor secretion signal sequence was performed in order to determine the effects of various deletions and substitutions on expression.

Risk factors for drug-related problems in elderly ambulatory patients.

Medication use among elderly patients in ambulatory care, home health care, and long-term care settings has become increasingly complicated during the past decade. Home intravenous therapy, multiple drug regimens to treat multiple chronic diseases, increased acuity of nonhospitalized patients, and increased longevity have placed elderly patients at increased risk for drug-related problems.