Harnessing antimicrobial peptides in endodontics.

Endodontic therapy includes various procedures such as vital pulp therapy, root canal treatment and retreatment, surgical endodontic treatment and regenerative endodontic procedures. Disinfection and tissue repair are crucial for the success of these therapies, necessitating the development of therapeutics that can effectively target microbiota, eliminate biofilms, modulate inflammation and promote tissue repair. However, no current endodontic agents can achieve these goals.

A novel approach for designing hands-on training programs using Quick Reference code-linked videos.

Providing training on the proper use of technology in the context of a large number of learners and limited faculty availability is a constant challenge to dental schools. We found the implementation of a QR-code-based autonomous program design to be efficient and effective at providing trainees hands-on training with newly installed perioperative equipment.

Interdisciplinary treatment for an adolescent with fusion of the left maxillary lateral and central incisors: A clinical report.

The interdisciplinary treatment provided for a 12-year-old boy with fusion of his left central and lateral incisors and concomitant distal space loss is described. His treatment was initiated with orthodontic therapy followed by endodontic treatment of the fused tooth. A conservative zirconia and porcelain cantilevered bonded fixed dental prosthesis was then completed to replace his left lateral incisor.

Single-centre, single-blinded, randomised, parallel group, feasibility study protocol investigating if mandibular advancement device treatment for obstructive sleep apnoea can reduce nocturnal gastro-oesophageal reflux (MAD-Reflux trial).

Introduction: Just under half of patients with obstructive sleep apnoea (OSA) also have gastro-oesophageal reflux disease (GORD). These conditions appear to be inter-related and continual positive airway pressure (CPAP) therapy, the gold standard treatment for OSA to prevent airway collapse, has been shown to reduce GORD. As the impact of mandibular advancement devices, a second-line therapy for OSA, on GORD has yet to be investigated, a feasibility study is needed prior to a definitive trial.

Development of KROHL, a tool for evaluating oral health knowledge.

Objectives: The authors aim to evaluate a scale assessing oral health knowledge, the KROHL (Knowledge Related to Oral Health Literacy) including the inter-rater reliability for scoring open-ended questions, internal consistency of the hypothesized scales, the discriminant validity of the resulting scale and its relationship to existing measures of oral health literacy.

Methods: The questionnaire was administered via face-to-face interviews to 144 volunteers recruited in the waiting areas of clinics throughout the NYU College of Dentistry.The KROHL questionnaire evaluates oral health knowledge by asking open-ended questions about the appearance, cause, treatment and prevention of caries, gum disease, oral cancer, tooth loss and malocclusion.

Evaluation of two implant-supported fixed partial denture abutment designs: Influence on screw surface characteristics.

Purpose: To compare screw surface characteristics between hemi-engaging and non-engaging implant-supported fixed partial denture (FPD) designs after cyclic loading.

Materials And Methods: Twenty-four implants measuring 4.3 × 10 mm were mounted on acrylic resin blocks.

Peri-implantitis after 40 years: Evidence, mechanisms, and implications: A mapping review.

Statement Of Problem: The high prevalence of peri-implantitis (PI) continues to plague patients and the disease is resistant to present treatment regimens. An analysis of the available research is lacking.

Purpose: Given the abundance and diversity of research on the topic of PI, the purpose of this mapping review was to synthesize the literature on the prevention of PI, the histopathology of the disease, the state of present therapeutics, and any emerging treatments.

Core Practices for Infection Prevention and Control in Oral Healthcare.

Infection prevention and control (IPC) is an essential part of every encounter with patients in a healthcare setting, including oral healthcare. To ensure best practices are being followed, dental healthcare personnel (DHCP) should be familiar with several guidelines from the Centers for Disease Control and Prevention, including the Core Infection Prevention and Control Practices. The core practices represent the foundation upon which all other IPC protocols are built.

Accuracy of the KontrolFlex AccuFile when used with the Root ZX electronic apex locator in vitro.

The aims of this study were to determine the efficacy of the KontrolFlex™ Accufile™ compared to the READY•STEEL™ Flexofile® using an electronic apex locator and to evaluate the instrument's design via scanning electron microscopy. Actual canal lengths of 30 extracted teeth were determined under magnification. An alginate model was used to determine experimental canal lengths with the Root ZX II apex locator (EAL) and size #10 Accufiles and Flexofiles.

Preload evaluation of 2 implant-supported fixed partial denture abutment designs.

Statement Of Problem: A hemi-engaging abutment design has been suggested to improve the stability of the implant-to-abutment interface compared with that of a fully nonengaging design to restore implant-supported fixed partial denture. However, controversy persists regarding the benefit of using a hemi-engaging abutment design and prompts the need for specific mechanical testing on the effect of these designs on screw preload under simulated clinical conditions.

Purpose: The purpose of this in vitro study was to determine whether significant differences in preload values of the screw before and after cyclic loading exist between hemi-engaging and nonengaging abutment fixed partial denture designs.

Infection of the oral cavity with SARS-CoV-2 variants: Scope of salivary diagnostics.

Coronaviruses, including SARS-CoV-2, have caused pandemics in the past two decades. The most prevalent SARS-CoV-2 variants of concern can re-infect individuals who have been previously infected with other variants or had protection from vaccines targeting the original SARS-CoV-2 variant. Given the high risk of transmission of coronavirus aerosols produced during dental procedures, it is important to understand the future risk of coronavirus infection for oral health professionals and to diagnose quickly early stages of outbreaks.

Dental hygiene students' participation as subjects in a randomized controlled trial: A full evidence-based dentistry experience.

Purpose: Demonstrate that dental hygiene students' participation in a randomized controlled trial comparing the plaque-removing capability of two toothbrushes provides a fuller understanding of the factors affecting the potential application of research to practice.

Methods: All students (N = 18) in a baccalaureate dental hygiene class were engaged in the design of a randomized controlled trial using the Consolidated Standards of Reporting Trials (CONSORT) standard and then participated as subjects in a staggered, repeated measures trial using plaque removal as the dependent variable and brush type, brush head wear, and time in study as independent variables. A debriefing of student participation and lessons learned from analyzing the results was conducted.

Guidelines for Medical Immobilization/Protective Stabilization for Your Practice.

Many patients with special healthcare needs present to medical, dental, and other health visits with behavioral, emotional, postural, and psychological issues. According to the American Academy of Developmental Medicine and Dentistry (AADMD) guidelines from 2017: "Clinical dental treatment is the most exacting and demanding medical procedure that persons with special needs undergo on a regular basis throughout their lifetime." Moreover, dental treatment is basically surgical in nature, usually requiring controlled placement of sharpened instruments in intimate proximity to the face, airway, and highly vascularized and innervated oral tissues.

Dental treatment of patients with prune belly syndrome.

Background: Prune belly syndrome (PBS), also known as Eagle-Barrett syndrome (EGBRS), is a rare congenital disease characterized by deficiency or absence of abdominal wall muscles, urological abnormalities, and bilateral cryptorchidism.

Types Of Studies Reviewed: A review of literature was done using four search engines (PubMed, Google Scholar, Scopus, Science Direct) and keywords (individually and in combinations): prune belly syndrome, PBS, Eagle-Barrett syndrome, dental manifestation, clinical manifestation, and psychological aspects. The search was run with no language restrictions and covered the 1965-2021 time period.

Influence of acidic pH on antimicrobial activity of different calcium silicate based-endodontic sealers.

Objective: To investigate the antibacterial activity of calcium silicate-based sealers (CSBSs) against Enterococcus faecalis biofilm in a neutral or acidic condition.

Materials And Methods: Dentin cylinders (4 mm length) were prepared and infected with 3-week-old E. faecalis.

From Restraint to Medical Immobilization/Protective Stabilization.

Clinical dental treatment is the most exacting and demanding medical procedure that persons with special needs undergo on a regular basis throughout their lifetime. Dental treatment is surgical in nature, usually requiring controlled placement of sharpened instrumentation in intimate proximity to the face, airway, and highly vascularized and inner aged oral tissues. Although approximately 90% of patients with special needs can and should be mainstreamed through any general dental practice, without significant behavioral guidance, techniques, or medical immobilization/protective stabilization, there has been a drastic shift toward pharmacologic management of these patients using various forms of sedation and general anesthesia.

Myofascial pain in temporomandibular disorders: Updates on etiopathogenesis and management.

Objectives: Temporomandibular disorders (TMDs) are an umbrella term encompassing disorders of both the temporomandibular joint (TMJD) and masticatory musculature (MMD). The objective of this review is to provide an overview of the etiopathogenesis, clinical features and diagnosis of MMD, and to summarize the current trends in the therapeutic management.

Methods: A review of the literature was performed from 1985 to 2020.

Reduction of headache intensity and frequency with maxillary stabilization splint therapy in patients with temporomandibular disorders-headache comorbidity: a systematic review and meta-analysis.

This systematic review and meta-analysis aimed to analyze the effectiveness of maxillary stabilization splint (SS) therapy to reduce headache (HA) intensity and HA frequency in patients with temporomandibular disorders (TMD)-HA comorbidity. Randomized controlled trials (RCTs) using full-arch coverage, hard resin, and maxillary SS therapy were included. Electronic databases, including Cochrane Library, MEDLINE through PubMed, Web of Science, and EMBASE, were searched.

A custom screw-retained implant-supported prosthesis for a patient with amelogenesis imperfecta: An 8-year clinical follow-up.

This clinical report with an 8-year follow-up describes the multidisciplinary management of a patient diagnosed with amelogenesis imperfecta. The rehabilitation included horizontal-guided bone regeneration, implant placement, use of a fixed interim prosthesis to preview the correction of occlusal disharmonies, and placement of a custom screw-retained definitive implant-supported restoration with a design that was retrievable and minimized maintenance problems.

Self-regeneration of an extensive bony defect following mandibular resection.

Spontaneous bone regeneration is a rapid and uncommon formation of new bone in a previous bone defect. Preservation of periosteum as the main source of osteogenesis, young age, and genetics are possible important factors related to this phenomenon.

Are teeth superior to implants? A mapping review.

Statement Of Problem: There is a long-held assumption that teeth are superior to implants because the periodontal ligament (PDL) confers a preeminent defense against biologic and mechanical challenges. However, adequate analysis of the literature is lacking. As a result, differential treatment planning of tooth- and implant-supported restorations has been compromised.