8,378 results match your criteria: "University of l'Aquila[Affiliation]"
Digit Health
December 2024
Department of Biological and Environmental Sciences and Technologies (DiSTeBA), Università del Salento, Lecce, Italy.
Objective: Osteoarthritis (OA), particularly knee OA, is a leading cause of disability and poses significant challenges in healthcare management. Mobile applications (apps) have emerged as potential tools to support therapeutic exercise by providing tailored programs, instructional content, and progress tracking. This systematic review evaluates the efficacy of mobile apps in enhancing therapeutic exercise for knee OA management.
View Article and Find Full Text PDFLife Sci
December 2024
"Aurel Ardelean" Institute of Life Sciences, "Vasile Goldis" Western University of Arad, 310144 Arad, Romania; Department of Histology, Faculty of Medicine, "Vasile Goldis" Western University of Arad, 310144 Arad, Romania. Electronic address:
Aims: COVID-19, caused by the SARS-CoV-2 virus, can lead to serious lung conditions, notably interstitial pulmonary fibrosis.
Main Methods: Our study tracked the progression of fibrosis markers in serial bronchoalveolar lavage (BAL) measurements collected from 16 COVID-19 patients at 1, 3, and 6 months post-infection. Additionally, BAL samples from 10 healthy control subjects were included.
Maturitas
December 2024
Department of Translational and Precision Medicine, Sapienza-University of Rome, Viale del Policlinico 155, Rome 00161, Italy. Electronic address:
Sleep-disordered breathing is a highly prevalent disorder with negative impact on healthcare systems worldwide. This condition has detrimental effects on cardiovascular health and quality of life, and is frequently associated with a variety of comorbidities, including cardiovascular disease, heart failure, diabetes and atrial fibrillation. Nevertheless, it remains frequently undiagnosed and undertreated, especially in specific populations.
View Article and Find Full Text PDFRadiol Med
December 2024
Department of Radiology, ASST Papa Giovanni XXIII Hospital, Piazza OMS, 1, 24127, Bergamo, Italy.
Coronary computed tomography angiography (CCTA) is a powerful tool to rule out coronary artery disease (CAD). In the last decade, myocardial perfusion CT (CTP) technique has been developed for the evaluation of myocardial ischemia, thereby increasing positive predictive value for diagnosis of obstructive CAD. A diagnostic strategy combining CCTA and perfusion acquisitions provides both anatomical coronary evaluation and functional evaluation of the stenosis, increasing the specificity and the positive predictive value of cardiac CT.
View Article and Find Full Text PDFFront Pediatr
December 2024
Laboratory of Neuromotor Physiology, Istituto di Ricovero e Cura a Carattere Scientifico Fondazione Santa Lucia, Rome, Italy.
Cerebral Palsy (CP) is a leading cause of childhood motor disability, making independent walking a crucial therapeutic goal. Robotic assistive devices offer potential to enhance mobility, promoting community engagement and quality of life. This is an observational report of 22 cases of children with CP in which we evaluated the Moonwalker exoskeleton (a dynamic moving aid system) usability, functional changes, and caregivers' perspectives based on the International Classification of Functioning (ICF).
View Article and Find Full Text PDFBMC Health Serv Res
December 2024
Golgi Redaelli Istitute, Milan, Italy.
Introduction: In the evolving healthcare landscape, technology has emerged as a key component in enhancing system efficiency and offering new avenues for patient rehabilitation. Despite its growing importance, detailed information on technology's specific use, types, and applications in clinical rehabilitation settings, particularly within the Italian framework, remains unclear. This study aimed to explore the use of technology and its needs by Physical Medicine and Rehabilitation medical doctors in Italy.
View Article and Find Full Text PDFRadiol Cardiothorac Imaging
December 2024
From the Department of Radiology, School of Medicine, Vita-Salute San Raffaele University, Via Olgettina 58-60, 20132 Milan, Italy (A. Palmisano, E.B., S.B., D.V., A.E.); Experimental Imaging Center, IRCCS San Raffaele Scientific Institute, Milan, Italy (A. Palmisano, E.B., M.C., D.V., A.E.); Academic Radiology Department of Translational Research, University of Pisa, Pisa, Italy (G.D.A., C.D.G., M.A., D.P., L.F., E.N.); Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, Department of Radiodiagnostics, Università di Brescia-Spedali Civili, Brescia, Italy (P.R., N.d.M., M.R., D.F.); Department of Emergency Radiology, University Hospital Careggi, Florence, Italy (A.R., S.P., V.M.); Department of Radiological Sciences, Oncology and Pathology, Sapienza University of Rome, Rome, Italy (L.M., G.C., N.G.); Department of Surgical Sciences, University of Turin, Turin, Italy (D.T., M.G., R.F.); Department of Diagnostic Imaging, Area of Cardiovascular and Interventional Imaging, Abruzzo Health Unit 1, L'Aquila, Italy (P.P.); Department of Biotechnological and Applied Clinical Science, University of L'Aquila, L'Aquila, Italy (E.D.C.); Diagnostic and Interventional Radiology Unit, BIOMORF Department, University Hospital Policlinico, Messina, Italy (T.D., L.R.M.L., A.B.); Department of Radiology, Santa Maria delle Grazie Hospital, Pozzuoli, Italy (S.D.); Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy (A. Ponsiglione, R.A., M.I.); Department of Radiology, AOU Cagliari, University of Cagliari, Cagliari, Italy (M.P., R.C., L.S.); Department of Radiology, Ospedale del Mare-ASL NA1 Centro, Naples, Italy (G.F., C.L.); Department of Radiology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy (V.S., S.S.); Department of Radiology, Ospedale Maggiore della Carità University Hospital, Novara, Italy (A.S., A.C.); and IRCCS Azienda Ospedaliero-Universitaria di Bologna, S. Orsola Hospital, University of Bologna, Italy (L.L.).
Purpose To determine the prevalence of mitral annular disjunction (MAD) in patients undergoing cardiac MRI for various clinical indications and to assess the association of MAD with arrhythmia, mitral valve prolapse (MVP), and myocardial alteration. Materials and Methods This study analyzed data from a retrospective observational registry of consecutive patients undergoing cardiac MRI for different clinical indications. Cardiac MRI examinations were performed from January 2019 to June 2019 at 13 Italian hospitals.
View Article and Find Full Text PDFHum Vaccin Immunother
December 2024
Department of Life, Health and Environmental Science, University of L'Aquila, L'Aquila, Italy.
We evaluated the efficacy of a booster dose of HBV in Italian medical students. We conducted a prospective observational study in students who had received a full course of anti-HBV vaccination for at least 15 y. Those with an anti-HBs titer <10 mIU/mL were offered a booster dose of the HBV vaccine and the antibody titer was reevaluated after 1 month.
View Article and Find Full Text PDFSensors (Basel)
November 2024
Research Unit of Electronics for Sensor Systems, Department of Engineering, University Campus Bio-Medico di Roma, 00128 Rome, Italy.
Electrical stimulation can be used in several applications such as fatigue reduction, muscle rehabilitation, neurorehabilitation, neuro-prosthesis and pain relief. Moreover, electrical stimulation can be used for drug delivery applications or body fluids extraction (e.g.
View Article and Find Full Text PDFJ Clin Med
December 2024
Interventional Cardiology, Sandro Pertini Hospital, 00157 Rome, Italy.
Cardio-cerebral vascular diseases due to atherosclerosis are still the leading cause of death worldwide. Low-density lipoprotein cholesterol (LDL-C) and apolipoprotein B have been identified as the primary factors responsible for the atherosclerotic process, with a causal effect. Many drugs aimed at reducing LDL-C levels are already on the market, acting in different ways in terms of mechanism of action, efficacy, and safety.
View Article and Find Full Text PDFCells
November 2024
Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Aging is a natural process that leads to time-related changes and a decrease in cognitive abilities, executive functions, and attention. In neuronal aging, brain cells struggle to respond to oxidative stress. The structure, function, and survival of neurons can be mediated by different pathways that are sensitive to oxidative stress and age-related low-energy states.
View Article and Find Full Text PDFTransl Neurodegener
December 2024
Laboratory for Research on Neurodegenerative Disorders, Istituti Clinici Scientifici Maugeri IRCCS, 27100, Pavia, Italy.
Eur Arch Psychiatry Clin Neurosci
December 2024
Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
The literature suggests that alterations in functional connectivity (FC) of the Salience Network (SN) may contribute to the manifestation of some clinical features of Autism Spectrum Disorder (ASD). The SN plays a key role in integrating external sensory information with internal emotional and bodily information. An atypical FC of this network could explain some symptomatic features of ASD such as difficulties in self-awareness and emotion processing and provide new insights into the neurobiological basis of autism.
View Article and Find Full Text PDFWorld J Urol
December 2024
Department of Urology, Rush University Medical Center, 1725 W. Harrison Street, Suite 970, Chicago, IL, 60612, USA.
Purpose: To evaluate the predictors of delayed discharge for patients undergoing robot-assisted partial nephrectomy (RAPN) at our Institution since the introduction of the single port (SP) robotic system.
Methods: We performed a retrospective review of our prospectively maintained database of patients undergoing RAPN from September 2020 to August 2024. Patients were categorized by the postoperative day of their discharge: POD1 (single overnight stay) or POD > 1 (more than one night stay).
Transl Lung Cancer Res
November 2024
Department of Pulmonary and Critical Care Medicine, Fuzhou General Hospital of Fujian Medical University, Dongfang Hospital of Xiamen University, The 900th Hospital of the Joint Logistic Support Force, People's Liberation Army of China, Fuzhou, China.
Int J Biol Sci
December 2024
Unit of Cell and Gene Therapies, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.
Extracellular vesicles (EV) have emerged as promising cell-free therapeutics in regenerative medicine. However, translating primary cell line-derived EV to clinical applications requires large-scale manufacturing and several challenges, such as replicative senescence, donor heterogeneity, and genetic instability. To address these limitations, we used a reprogramming approach to generate human induced pluripotent stem cells (hiPSC) from the young source of cord blood mesenchymal stem/stromal cells (CBMSC).
View Article and Find Full Text PDFFront Psychol
November 2024
Department of Physiology and Pharmacology "Vittorio Erspamer", Sapienza University of Rome, Rome, Italy.
Cell Tissue Res
December 2024
Department of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Via Alfonso Borelli 50 - 00161, Rome, Italy.
Alpha-synuclein (α-syn) is widely expressed in presynaptic neuron terminals, and its structural alterations play an important role in the pathogenesis of Parkinson's disease (PD). Aggregated α-syn has been found in brain, in the peripheral nerves of the enteric nervous system (ENS) and in the intestinal neuroendocrine cells during synucleinopathies and inflammatory bowel disorders. In the present study, we evaluated the histomorphological features of murine colon with 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis, a common model of colitis.
View Article and Find Full Text PDFDiabetes Metab Res Rev
January 2025
Department of Experimental Medicine, Sapienza University, Rome, Italy.
Context: The mechanisms underlying bone fragility and increased fracture risk observed in individuals with type 2 diabetes (T2D) are not yet fully elucidated. Previous research has suggested a role for neuropeptides in regulating bone metabolism; however, the contribution of the neuropeptide Neurotensin (NT), which is thoroughly implicated in T2D and cardiovascular disease, has not been investigated in this context.
Objective: To study the relationship between circulating levels of the NT precursor proneurotensin (proNT) and bone mineralisation in T2D women.
Ann Ig
December 2024
Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy.
Background: The term 'Missed Nursing Care' (MNC) refers to any aspect of nursing care that is not delivered, partially delivered, or delayed. MNC has significant negative consequences, including adverse patient outcomes, safety risks, and decreased job satisfaction. While extensively studied in hospitals, MNC in community healthcare settings, remains under-researched, especially in Italy.
View Article and Find Full Text PDFStroke
December 2024
Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy (M.F., E.D.M., F.D.S., F. Pistoia, R.O., S.S.).
Background: Sex may impact clinical outcomes in patients with stroke treated with dual antiplatelet therapy (DAPT). We aimed to investigate the sex differences in the short-term outcomes of DAPT within a real-world population of patients with noncardioembolic mild-to-moderate ischemic stroke or high-risk transient ischemic attack.
Methods: We performed a propensity score-matched analysis from a prospective multicentric cohort study (READAPT [Real-Life Study on Short-Term Dual Antiplatelet Treatment in Patients With Ischemic Stroke or Transient Ischemic Attack]) by including patients with noncardioembolic mild-to-moderate stroke (National Institutes of Health Stroke Scale score of 0-10) or high-risk transient ischemic attack (age, blood pressure, clinical features, duration of transient ischemic attack, presence of diabetes [ABCD] ≥4) who initiated DAPT within 48 hours of symptom onset.
Nanoscale
December 2024
Department of Physics "E. R. Caianiello", University of Salerno, via Giovanni Paolo II, 84084 Fisciano, Salerno, Italy.
Devices based on transition metal dichalcogenide nanotubes hold great potential for electronic and optoelectronic applications. Herein, the electrical transport and photoresponse characteristics of a back-gate device with a channel made of a single tungsten disulfide (WS) nanotube are investigated as functions of electric stress, ambient pressure, and illumination. As a transistor, the device exhibits p-type conduction, which can be transformed into ambipolar conduction at a high drain-source voltage.
View Article and Find Full Text PDFRiv Psichiatr
December 2024
Department of Biotechnological and Applied Clinical Sciences (DISCAB), University of L'Aquila, Italy.
Eur J Intern Med
December 2024
University of L'Aquila, MeSVA Department, Hypertension and Cardiovascular Prevention Center, UOC Internal Medicine and Nephrology, San Salvatore Hospital, L'Aquila, Italy. Electronic address:
Am J Hematol
December 2024
Internal Medicine Department, Tenon Hospital, AP-HP, Paris, France.