2,802 results match your criteria: "University of Wollongong and Illawarra Health & Medical Research Institute[Affiliation]"
Contemp Nurse
August 2024
Prince of Wales Hospital (South Eastern Sydney Local Health District), Randwick, NSW, 2031, Australia.
Unlabelled: Person-centred care is an international healthcare priority. Strategies are needed to support nurses and midwives to understand the meaning of person-centredness and support them to embed this philosophy into practice. Clinical supervision has been proposed as a strategy to support this but requires more evidence.
View Article and Find Full Text PDFIntern Med J
October 2024
Endocrine and Metabolic Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Background: Insulin degludec/insulin aspart (IDegAsp) is a fixed-ratio co-formulation of insulin degludec and insulin aspart for the treatment of people with diabetes and suboptimal glycaemic control. Few real-world studies of IDegAsp treatment have been conducted. Here, we report results from the Australian cohort of the global ARISE study of real-world IDegAsp use.
View Article and Find Full Text PDFStress Health
October 2024
University of Wollongong, Wollongong, New South Wales, Australia.
Health Promot J Austr
January 2025
School of Health and Society, Faculty of the Arts, Social Sciences and Humanities, University of Wollongong, Wollongong, Australia.
Issue Addressed: Munch & Move is a New South Wales (NSW) Ministry of Health program offering family day care (FDC) educators training to support children's healthy behaviours. This study examined educators' nutrition, physical activity and screen time practices and relationships between Munch & Move training and professional development (PD) on these practices.
Methods: NSW FDC educators (n = 186) completed an online survey from July 2020-June 2021.
medRxiv
August 2024
Colorectal Oncogenomics Group, Department of Clinical Pathology, The University of Melbourne, Parkville, VIC, 3010, Australia.
Int J Mol Sci
August 2024
Molecular Horizons, School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2500, Australia.
The keratinocyte carcinomas, basal cell carcinoma (BCC), and cutaneous squamous cell carcinoma (cSCC), are the most common cancers in humans. Recently, an increasing body of literature has investigated the role of miRNAs in keratinocyte carcinoma pathogenesis, progression and their use as therapeutic agents and targets, or biomarkers. However, there is very little consistency in the literature regarding the identity of and/or role of individual miRNAs in cSCC (and to a lesser extent BCC) biology.
View Article and Find Full Text PDFInt J Psychophysiol
October 2024
Graduate School of Medicine, Faculty of Science, Medicine and Health, University of Wollongong, Australia; Illawarra Health and Medical Research Institute, University of Wollongong, 2522, Australia. Electronic address:
Dog ownership has been linked to numerous benefits to human health and wellbeing. However, due to the lack of previous research on changes to brain activity during interactions with pet dogs, the underlying psychophysiological mechanisms are still unclear. The aim of the present study was to examine changes in heart rate (HR), heart rate variability (HRV), and electroencephalogram (EEG) power during interactions between dog owners and their pet dog.
View Article and Find Full Text PDFBiofabrication
August 2024
Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW 2522, Australia.
Three-dimensional (3D) tissue models have gained recognition for their improved ability to mimic the native cell microenvironment compared to traditional two-dimensional models. This progress has been driven by advances in tissue-engineering technologies such as 3D bioprinting, a promising method for fabricating biomimetic living tissues. While bioprinting has succeeded in generating various tissues to date, creating neural tissue models remains challenging.
View Article and Find Full Text PDFImplement Sci
July 2024
Susan Wakil School of Nursing and Midwifery, Faculty of Medicine and Health, RC Mills Building, University of Sydney, Camperdown, NSW, 2006, Australia.
Surgery
October 2024
School of Computing and Information Technology, Faculty of Engineering and Information Sciences, University of Wollongong, Wollongong, New South Wales, Australia. Electronic address:
Background: This study aims to identify the common pathways of appendicectomy, the most common emergency surgery in Australia's public hospitals and any variations within a regional public health district in New South Wales, Australia.
Methods: We analyzed the electronic medical records of 3,943 patients who underwent appendicectomy between January 2014 and July 2020 at 2 hospitals in the Illawarra Shoalhaven Local Health District, New South Wales, Australia, using the PM approach for surgical pathway identification and subsequent statistical analyses.
Results: Among 3,943 patients, 3,606 (91.
Int J Biochem Cell Biol
September 2024
Children's Cancer Research Unit, Kids Research, The Children's Hospital at Westmead, Westmead, Australia; The University of Sydney, Discipline of Child and Adolescent Health, The Children's Hospital at Westmead, Westmead, Australia. Electronic address:
Diffuse Intrinsic Pontine Gliomas (DIPGs) are deadly brain cancers in children for which there is no effective treatment. This can partly be attributed to preclinical models that lack essential elements of the in vivo tissue environment, resulting in treatments that appear promising preclinically, but fail to result in effective cures. Recently developed co-culture models combining stem cell-derived brain organoids with brain cancer cells provide tissue dimensionality and a human-relevant tissue-like microenvironment.
View Article and Find Full Text PDFMed J Aust
August 2024
Sydney School of Health Sciences, University of Sydney, Sydney, NSW.
Objectives: To estimate the long term cost savings, return on investment, and gain in quality-adjusted life years (QALYs) that could be achieved by a national anterior cruciate ligament (ACL) injury prevention program for amateur football (soccer) players in Australia.
Study Design: Markov model decision analysis.
Setting, Participants: Two hypothetical scenarios including all amateur football players in Australia (340 253 players): no intervention, and a national ACL injury prevention program.
Int J Qual Health Care
July 2024
Early Start, Faculty of the Arts, Social Sciences and Humanities, University of Wollongong, Wollongong, NSW 2522, Australia.
As technology continues to advance, it is important to understand how website-based tools can support quality improvement. Website-based tools refer to resources such as toolkits that users can access and use autonomously through a dedicated website. This review examined how website-based tools can support healthcare professionals with quality improvement, including the optimal processes used to develop tools and the elements of an effective tool.
View Article and Find Full Text PDFHeliyon
June 2024
School of Medical and Indigenous Health Sciences, University of Wollongong, NSW, Australia.
Repressor element-1 silencing transcription factor (REST) is a transcriptional repressor involved in neurodevelopment and neuroprotection. REST forms a complex with the REST corepressors, CoREST1, CoREST2, or CoREST3 (encoded by , , and , respectively). Emerging evidence suggests that the CoREST family can target unique genes independently of REST, in various neural and glial cell types during different developmental stages.
View Article and Find Full Text PDFClin Nutr ESPEN
October 2024
School of Medicine, Smart Foods Centre, Illawarra Health and Medical Research Institute, University of Wollongong, Building 32, Northfields Ave, Keiraville, NSW, 2500, Australia.
Australas Emerg Care
December 2024
Faculty of Medicine and Health, The University of Sydney, Susan Wakil School of Nursing and Midwifery, Camperdown, NSW, Australia.
Background: The emergency resuscitation nurse is a challenging and specialised role at the forefront of critical care practice in the emergency department. Despite their extensive specialist knowledge and skill requirements, in Australia there is no state-wide or nationally agreed approach to how to best provide training that meets a set of fixed objectives and requisite skills for resuscitation nurses. Due to an ageing nursing population and increasing workforce attrition, an efficacious accelerated pathway to acquire specialist resuscitation nursing knowledge, is necessary.
View Article and Find Full Text PDFSci Adv
July 2024
Cancer Ecosystems Program, Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.
Pancreatic ductal adenocarcinoma (PDAC) is characterized by increasing fibrosis, which can enhance tumor progression and spread. Here, we undertook an unbiased temporal assessment of the matrisome of the highly metastatic KPC (, , ) and poorly metastatic KPC (, , ) genetically engineered mouse models of pancreatic cancer using mass spectrometry proteomics. Our assessment at early-, mid-, and late-stage disease reveals an increased abundance of nidogen-2 (NID2) in the KPC model compared to KPC, with further validation showing that NID2 is primarily expressed by cancer-associated fibroblasts (CAFs).
View Article and Find Full Text PDFTrials
June 2024
IMPACT, School of Medicine, Deakin University, Geelong, Australia.
Background: There are no approved pharmacotherapies for methamphetamine use disorder. Two preliminary phase 2 randomised controlled trials have found mirtazapine, a tetracyclic antidepressant, to be effective in reducing methamphetamine use. The proposed Tina Trial is the first phase 3 placebo-controlled randomised trial to examine the effectiveness and safety of mirtazapine as an outpatient pharmacotherapy for methamphetamine use disorder.
View Article and Find Full Text PDFSci Rep
June 2024
Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW, 2522, Australia.
Disrupted proteome homeostasis (proteostasis) in amyotrophic lateral sclerosis (ALS) has been a major focus of research in the past two decades. However, the proteostasis processes that become disturbed in ALS are not fully understood. Obtaining more detailed knowledge of proteostasis disruption in association with different ALS-causing mutations will improve our understanding of ALS pathophysiology and may identify novel therapeutic targets and strategies for ALS patients.
View Article and Find Full Text PDFIndividuals experiencing socio-economic disadvantage face higher rates of food insecurity and health disparities. This study explored the perceptions, attitudes, and knowledge of individuals providing nutrition services, and users of these services, to identify nutrition needs and inform potential strategies for addressing diet-related health inequities. Semi-structured interviews were conducted utilizing a phenomenological approach to explore lived experiences, beliefs, and perceptions influencing nutrition-related health.
View Article and Find Full Text PDFPalliat Med
July 2024
Palliative Care Services, Illawarra Shoalhaven Local Health District, Wollongong, NSW, Australia.
Background: Tracheostomy ventilation in motor neurone disease is an uncommon life-sustaining treatment. Best practice is having a plan for ventilation withdrawal, but the literature to guide practice is limited. Case reports have documented standard doses of opioids and benzodiazepines used for sedation in such cases.
View Article and Find Full Text PDFJ Addict Med
November 2024
From the Faculty of Medicine, University of New South Wales, Sydney, Australia (NH, ElB and EmB, NE, MM); Drug and Alcohol Services, South Eastern Sydney Local Health District, Sydney, Australia (NH, EB, EB, AD, KM, LM, RD, NL); New South Wales (NSW) Drug and Alcohol Clinical Research and Improvement Network, Sydney, Australia (EB, EB, AD, KM, LM, RD, NE, MM, DR, KJS, NL); School of Population Health, University of NSW, Sydney, Australia (EB, AD); Specialty of Addiction Medicine, Sydney University, Sydney, Australia (EB, LM, RD, MM, NL); Alcohol and Drug Service, St Vincent's Hospital Sydney, Sydney, Australia (NE, KJS); National Centre for Clinical Research on Emerging Drugs, Australia, Sydney, Australia (NE, KJS); Drug and Alcohol Services, Northern Sydney Local Health District, Sydney, Australia (MM); Drug and Alcohol Services, Illawarra Shoalhaven Local Health District, Wollongong, Australia (DR); School of Psychological Sciences, University of Tasmania, Hobart, Australia (RB); National Drug and Alcohol Research Centre, University of NSW, Sydney, Australia (RB, AS, MF); and Poche Centre for Indigenous Health, University of Queensland, Brisbane, Australia (AS).
Objectives: Although factors associated with alcohol use have been researched at a population level, descriptions of the alcohol and other drug (AOD) treatment-seeking population in New South Wales (NSW), Australia, are limited. This study addresses this gap by analyzing sociodemographic and health characteristics in the NSW AOD treatment-seeking population.
Methods: Self-reported Australian Treatment Outcomes Profile data on substance use, health ratings, and sociodemographic factors were acquired from public AOD services (offering services from counseling to ambulatory/inpatient withdrawal management) in 6 administrative health districts from 2016 to 2019 (n = 14,287).
Issues Ment Health Nurs
June 2024
School of Nursing and Midwifery, University of Sydney, Sydney, Australia.
This review explores the transformative impact of sensory modulation interventions in acute inpatient mental health care setting utilising meta-ethnography. The methodology by Noblit & Hare guided the approach to creating the review. Searches of articles published within the previous 10 years were conducted in Cumulative Index of Nursing and Allied Health Literature (CINAHL), MEDLINE, and PsycINFO.
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