Hemodynamic versus hydrodynamic effects of Guglielmi detachable coils on intra-aneurysmal pressure and flow at varying pulse rate and systemic pressure.

Background And Purpose: Alterations in intra-aneurysmal pressure and flow have been observed after treatment with Guglielmi detachable coils (GDCs). We wished to determine whether these changes could be assigned to a hydrodynamic effect of the coils themselves or a compound effect of coils plus thrombus formation.

Methods: Intra-aneurysmal pressure and flow were measured with a 0.

Endovascular treatment of experimental canine aneurysms: feasibility with MR imaging guidance.

Purpose: To evaluate the feasibility of using magnetic resonance (MR) imaging to guide and monitor endovascular therapeutic procedures.

Materials And Methods: Endovascular therapeutic procedures were performed with MR imaging guidance in eight dogs by using a 1.5-T MR unit with echo-planar imaging capabilities.

Estimating length of survival in end-stage cancer: a review of the literature.

Accurately estimating survival times in patients with end-stage cancer is on ongoing challenge for palliative care clinicians. Psychosocial as well as physiological factors have been thought to influence the length of the terminal phase of illness, but conclusive findings remain elusive. This review examines the studies that have addressed the issue using observable, measurable criteria associated with physiological, clinical status.

Cytogenetic instability with balanced chromosome changes in an SV40 transformed human uroepithelial cell line.

Cytogenetic analysis at the 15th, 34th, 50th, and 56th passages of an SV40 immortalized human uroepithelial cell line (SV-HUC-1) showed continuous chromosome change and marker formation. Throughout these passages the transformed cells maintained their epithelial morphology, were SV40 T antigen positive, did not shed infectious SV40 virus, and were repeatedly found to be nontumorigenic when innoculated into athymic nude mice. Each of the passages studied was characterized by extensive karyotypic changes due to formation, rearrangement, and disappearance of different markers.

An objective assessment of voice production after radiation therapy for stage I squamous cell carcinoma of the glottis.

Radiation therapy has been the primary treatment for early glottic carcinoma, especially when restoration of normal voice is essential; yet objective evidence of the status of vocal function after treatment is lacking. The purpose of this study was to assess vocal characteristics of patients with glottic carcinoma after they had undergone radiation therapy. Twenty males, who had previously been treated with external beam irradiation for T1N0M0 squamous cell carcinoma with no subsequent evidence of recurrence, volunteered for this study.