Evaluation of the adverse effects of subcutaneous carprofen over six days in healthy cats.

This study evaluated the adverse effects of carprofen in seven healthy cats. Values for CBC, biochemical profiles and platelet aggregation were measured before and at seven days after SID treatment with subcutaneous carprofen: 4 mg/kg (day 1), 2mg/kg (day 2 and 3) and 1mg/kg (day 4 and 6) (CG) or 0.35 ml of saline (SG) for six days in a randomized, blinded, cross-over study with a four-week washout period.

Disease management of dairy calves and heifers.

This article focuses on the most important diseases of dairy calves and heifers and presents clinical approaches that can improve detection, diagnosis, and treatment of herd-based problems. A systematic herd investigation strategy is pivotal to define the problems, understand important risk factors, develop a plan, and make recommendations for disease management accurately. A review of records, colostrum and feeding routines, housing and bedding management, routine procedures, vaccination, and treatment protocols begins the investigation and determines which diagnostic procedures and testing strategies are most useful.

Common malignant musculoskeletal neoplasms of dogs and cats.

Malignancies of the musculoskeletal system in dogs and cats can be categorized as either primary or metastatic within the bony or soft structures that comprise the musculoskeletal system. By far, the most common tumor that affects the musculoskeletal system in dogs is osteosarcoma. The most common tumors that affect the musculoskeletal system in cats are injection site sarcomas.

Efficacy and safety of transdermal methimazole in the treatment of cats with hyperthyroidism.

The objective of this study was to determine whether transdermal methimazole was as safe and effective as oral methimazole for the control of hyperthyroidism in cats. Forty-seven cats with newly diagnosed hyperthyroidism were randomized to receive either transdermal methimazole in pluronic lecithin organogel (PLO; applied to the inner pinna), or oral methimazole (2.5 mg q12h for either route).

Managing the production, storage, and delivery of colostrum.

Provision of an adequate immunoglobulin mass to dairy calves is an essential component for survival, health, and future productivity. To prevent FPT of immunity due to suckling of the dam, newborn dairy calves should be removed from the calving area within 30 minutes of birth. First and later lactation cows are suitable colostrum donors, provided they are healthy, well-vaccinated, have had optimal transition management, and an appropriate dry-period length.

Orthogonal view analysis for evaluating the femoral component position of total hip implants in dogs using postoperative radiographs.

Objective: To show the ability to obtain repeatable, accurate, quantitative data to assess the position of the femoral component of canine total hip implants using postoperative radiographs.

Study Design: Cadaveric study and clinical trial.

Animals: Five cadaveric canine femurs and 4 patients.

Intramyocardial arterial cushions of coronary vessels in animals and humans: morphology, occurrence and relation to heart disease.

The existence of coronary endoarterial cushions (CEC) in the human heart as nonpathological, functional entities has been debated, and CEC have been sparsely reported in animals. Arterial cushions are localized thickenings that protrude into the lumen of specific arteries. We have identified CEC in the rhesus monkey, dog, sheep, goat, pig, rabbit and rat, and in the human heart.

Characterization and identification of interleukin-1 receptors on bovine fibroblasts.

Interleukin-1 (IL-1), a pro-inflammatory cytokine, initiates its many biological effects by first binding to cell-surface receptors. Prior to this study, there were no published reports addressing the nature of the bovine IL-1 receptor. In this study, we characterized and identified cell-surface IL-1 receptors on bovine fibroblasts.

Treatment of cardiovascular disease in cattle.

Cardiac diseases of cattle may involve valvular structures, myocardium, pericardium, or blood vessels and are manifested by the clinical signs of cardiac dysrhythmias, cardiac murmurs, generalized edema, muffled heart sounds, jugular venous distention, jugular venous pulsations, pulmonary edema, pleural effusion, or ascites. Digoxin, quinidine, and furosemide can be used effectively to control signs of CHF and cardiac arrhythmias. Combination antimicrobial therapy can be successful for cows with infective endocarditis and thrombophlebitis.

Immortalized retinal neurons used as immunogen for the generation of cell-specific antisera.

We have recently described a class of immortalized neurons which were derived from retinal tumors induced in PNMT-SV40 transgenic mice (TgBri59)9. These neurons possess a differentiated neuronal phenotype which includes the elaboration of extensive neurite processes and the expression of markers specific for amacrine and horizontal neurons, as well as the expression of the neurofilament triplet proteins. As these 'RT-1' neurons are derived from a restricted set of retinal neurons, they represent an enriched source of immunogen for the production of cell-specific antisera.

Equine bandaging techniques.

Topical medications and bandages play an important role in the management of equine wounds. Certain water-soluble antibacterial ointments (povidone-iodine, polymixin-neosporin-bacitracin) may be appropriate for use on contaminated wounds. A well-designed equine bandage is usually composed of primary, secondary, and tertiary layers.

Erythrocytic rickettsia and protozoa of the dog and cat.

This article summarizes the biologic and clinical features of the rickettsia and protozoa of canine and feline erythrocytes that are significant in North America: Haemobartonella canis, Haemobartonella felis, Cytauxzoon felis, Babesia canis, and Babesia gibsoni.