Feelings of stigmatization in patients with rosacea.

Background: Rosacea is a chronic facial disease that may lead to feelings of stigmatization, which can negatively impact psychological and social well-being.

Objective: The aim of this study was to evaluate different aspects of rosacea that could contribute to feelings of stigmatization.

Methods: An online survey of a representative sample of the adult population in the UK, France, Germany and US was conducted to identify patients with rosacea based on presence of three or more clinical features.

How People with Facial Acne Scars are Perceived in Society: an Online Survey.

Introduction: Atrophic scarring occurs throughout the course of inflammatory acne and across the spectrum of severity. This study evaluates perceptions of the general population toward individuals with clear skin and acne scars.

Methods: An online survey administered in the USA, UK, Japan, Germany, France and Brazil to respondents 18 years and over presented three facial pictures of clear skin or digitally superimposed acne scars (but no active acne lesions) in a random fashion.

A treatment for severe nodular acne: a randomized investigator-blinded, controlled, noninferiority trial comparing fixed-dose adapalene/benzoyl peroxide plus doxycycline vs. oral isotretinoin.

Background: Oral isotretinoin (ISO) is the gold standard for severe nodular acne. However, as some patients are unwilling or unable to take, or are intolerant to, ISO, other options are needed.

Objectives: To compare efficacy and safety of oral ISO vs.

Correlation of photographic images from the Leeds revised acne grading system with a six-category global acne severity scale.

Background: Few global acne grading systems include individualized assessments of chest and back as well as face. The Leeds revised acne grading system is based on photographic images while the Comprehensive Acne Severity Scale (CASS) is based on textual descriptions. There exists an unmet need for a global scale based on both text and photos.

Efficacy and safety of combined ethinyl estradiol/drospirenone oral contraceptives in the treatment of acne.

Acne is a common disorder affecting the majority of adolescents and often extends into adulthood. The central pathophysiological feature of acne is increased androgenic stimulation and/or end-organ sensitivity of pilosebaceous units leading to sebum hypersecretion and infundibular hyperkeratinization. These events lead to Propionibacterium acnes proliferation and subsequent inflammation.