346 results match your criteria: "University of Washington Bothell[Affiliation]"

In the United States of America, the Federal Communications Commission's repeal of the popular Open Internet Order (a.k.a 'net neutrality') has yielded pointed criticism from many different sectors, but it has yet to be examined for its potential effect on the public's health.

View Article and Find Full Text PDF

Purpose Of Review: The purpose of this review is to examine current sexual health education technologies for adolescents and identify gaps in knowledge. Disparities in sexual health education are prominent and mainly affect young women of color. As a result, the use of technology to reach these marginalized populations could potentially invoke change.

View Article and Find Full Text PDF

Chronic pain is a leading cause of disability among active duty service members in the U.S. armed forces.

View Article and Find Full Text PDF

Effective interprofessional (IP) team-based care is critical to enhance the delivery of efficient care and improve nursing and IP team outcomes. This study aims to review the most recent IP team intervention studies that focused on outcomes related to nursing and IP teams. PubMed, CINAHL, PsycINFO, and Embase were searched for existing literature published between January 2011 and December 2016.

View Article and Find Full Text PDF

US particulate matter air quality improves except in wildfire-prone areas.

Proc Natl Acad Sci U S A

July 2018

Department of Atmospheric Sciences, University of Washington, Seattle, WA 98195;

Using data from rural monitoring sites across the contiguous United States, we evaluated fine particulate matter (PM) trends for 1988-2016. We calculate trends in the policy-relevant 98th quantile of PM using Quantile Regression. We use Kriging and Gaussian Geostatistical Simulations to interpolate trends between observed data points.

View Article and Find Full Text PDF

Intrinsically disordered proteins (IDPs) make up a large class of proteins that lack stable structures in solution, existing instead as dynamic conformational ensembles. To perform their biological functions, many IDPs bind to other proteins or nucleic acids. Although IDPs are unstructured in solution, when they interact with binding partners, they fold into defined three-dimensional structures via coupled binding-folding processes.

View Article and Find Full Text PDF

Biological steroids were traditionally thought to be synthesized exclusively by the adrenal glands and gonads. Recent decades have seen the discovery of neurosteroid production that acts locally within the central nervous system to affect physiology and behavior. These actions include, for example, regulation of aggressive behavior, such as territoriality, and locomotor movement associated with migration.

View Article and Find Full Text PDF

The role of vasopressin in olfactory and visual processing.

Cell Tissue Res

January 2019

Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.

Neural vasopressin is a potent modulator of behaviour in vertebrates. It acts at both sensory processing regions and within larger regulatory networks to mediate changes in social recognition, affiliation, aggression, communication and other social behaviours. There are multiple populations of vasopressin neurons within the brain, including groups in olfactory and visual processing regions.

View Article and Find Full Text PDF

The detection of gravitational waves with Advanced LIGO and Advanced Virgo has enabled novel tests of general relativity, including direct study of the polarization of gravitational waves. While general relativity allows for only two tensor gravitational-wave polarizations, general metric theories can additionally predict two vector and two scalar polarizations. The polarization of gravitational waves is encoded in the spectral shape of the stochastic gravitational-wave background, formed by the superposition of cosmological and individually unresolved astrophysical sources.

View Article and Find Full Text PDF

Complex microbial communities shape the dynamics of various environments, ranging from the mammalian gastrointestinal tract to the soil. Advances in DNA sequencing technologies and data analysis have provided drastic improvements in microbiome analyses, for example, in taxonomic resolution, false discovery rate control and other properties, over earlier methods. In this Review, we discuss the best practices for performing a microbiome study, including experimental design, choice of molecular analysis technology, methods for data analysis and the integration of multiple omics data sets.

View Article and Find Full Text PDF

Mississippi has some of the most pronounced racial disparities in HIV infection in the country; African Americans comprised 37% of the Mississippi population but represented 80% of new HIV cases in 2015. Improving outcomes along the HIV care continuum, including linking and retaining more individuals and enhancing adherence to medication, may reduce the disparities faced by African Americans in Mississippi. Little is understood about clergy's views about the HIV care continuum.

View Article and Find Full Text PDF

Critical perspectives on the 'end of AIDS'.

Glob Public Health

August 2018

c Department of Sociomedical Sciences , Mailman School of Public Health, Columbia University, New York , USA.

This special symposium critically examines optimistic promises about an imminent 'end of AIDS,' currently circulating in global health discourse and policy. We aim not simply to interrogate the discourse surrounding calls to end AIDS, but to also explore the broader practices, contexts, and policy landscapes that have transformed the global HIV response during the fourth decade of the epidemic and allowed this discourse to gain such political traction. In this introduction we preview the collection's five substantive papers, which delve beneath the 'end of AIDS' rhetoric, bringing greater realism as well as resolve together with empirical evidence about the state of efforts to end AIDS in diverse locations and populations.

View Article and Find Full Text PDF

The LIGO Scientific and Virgo Collaborations have announced the event GW170817, the first detection of gravitational waves from the coalescence of two neutron stars. The merger rate of binary neutron stars estimated from this event suggests that distant, unresolvable binary neutron stars create a significant astrophysical stochastic gravitational-wave background. The binary neutron star component will add to the contribution from binary black holes, increasing the amplitude of the total astrophysical background relative to previous expectations.

View Article and Find Full Text PDF

Specialty-care access for community health clinic patients: processes and barriers.

J Multidiscip Healthc

February 2018

School of Nursing and Health Studies, University of Washington Bothell, Bothell, WA, USA.

Introduction: Community health clinics/centers (CHCs) comprise the US's core health-safety net and provide primary care to anyone who walks through their doors. However, access to specialty care for CHC patients is a big challenge.

Materials And Methods: In this descriptive qualitative study, semistructured interviews of 37 referral coordinators of CHCs were used to describe their perspectives on processes and barriers to patients' access to specialty care.

View Article and Find Full Text PDF

Objective Evaluate the efficacy of a 12 month nursing case-management intervention over a period of 18 months, 6 months after the end of intervention, for families of children attention deficit hyperactivity disorder (ADHD). Methods Mother and child dyads were enrolled to participate in a randomized controlled clinical trial. Children were 4-18 years old.

View Article and Find Full Text PDF

Objectives Test the 12-month efficacy of an inclusive non-diagnosis-specific, parent education program with seven in-person sessions. Methods Parents of 110 children, 2-11 years old, with a variety of special health care conditions, were recruited to participate in a randomized clinical trial. At twelve months data from 104 parents were available for longitudinal analysis.

View Article and Find Full Text PDF

First Search for Nontensorial Gravitational Waves from Known Pulsars.

Phys Rev Lett

January 2018

Jodrell Bank Centre for Astrophysics, School of Physics and Astronomy, University of Manchester, Manchester M13 9PL, United Kingdom.

Article Synopsis
  • * The analysis focused on detecting continuous signals from pulsars and did not depend on any specific gravity theory.
  • * After examining data from advanced LIGO, we found no signs of these gravitational waves, but established upper limits for scalar and vector strains that are similar to existing limits for tensor strain.
View Article and Find Full Text PDF

Heart disease is the leading cause of mortality in the U.S. with approximately 610,000 people dying every year.

View Article and Find Full Text PDF

Community psychology (CP) abandoned the clinic and disengaged from movements for community mental health (CMH) to escape clinical convention and pursue growing aspirations as an independent field of context-oriented, community-engaged, and values-driven research and action. In doing so, however, CP positioned itself on the sidelines of influential contemporary movements that promote potentially harmful, reductionist biomedical narratives in mental health. We advocate for a return to the clinic-the seat of institutional power in mental health-using critical clinic-based inquiry to open sites for clinical-community dialogue that can instigate transformative change locally and nationally.

View Article and Find Full Text PDF

Objective: The obesity paradox has been documented in aged populations, yet it remains unclear if this paradox persists for physical and cognitive outcomes in community-dwelling older adult populations. Our study examines associations between body mass index (BMI) classification, cognitive function, and physical function. We also investigate whether these associations are modified by race or age.

View Article and Find Full Text PDF

In the United States, one in 60,000 adults live with Crouzon Syndrome (CS) and facial malformations. Phenomenological studies about their lived experiences and quality of life are lacking. The purpose of this participatory action research study was to gain a richer understanding of the perceived biopsychosocial and socioecological factors that impact quality of life for adults living with CS using Photovoice.

View Article and Find Full Text PDF

Evolution on the bright side of life: microorganisms and the evolution of mutualism.

Ann N Y Acad Sci

June 2018

Biological Sciences Division, School of STEM, University of Washington Bothell, Bothell, Washington.

Mutualistic interactions, where two interacting species have a net beneficial effect on each other's fitness, play a crucial role in the survival and evolution of many species. Despite substantial empirical and theoretical work in past decades, the impact of these interactions on natural selection is not fully understood. In addition, mutualisms between microorganisms have been largely ignored, even though they are ecologically important and can be used as tools to bridge the gap between theory and empirical work.

View Article and Find Full Text PDF
Article Synopsis
  • The sulfate-reducing bacterium Hildenborough evolved rapid adaptations to salt stress over 5,000 generations, showcasing significant genetic and phenotypic changes, particularly in the clone ES10-5.
  • Differences between ES10-5 and another well-adapted clone, ES9-11, highlighted new mutations in ES10-5 related to salt tolerance, along with increased levels of glutamate and specific phospholipid fatty acids under high-salinity conditions.
  • Enhanced growth energy efficiency and changes in gene expression related to osmolyte and energy metabolism were key factors associated with improved salt tolerance in the evolved strains.
View Article and Find Full Text PDF

Discussions of community psychology (CP) ethics often examine how we might best uphold CP values in community-based practice. However, for many community psychologists in faculty positions, our main domain of practice is the undergraduate classroom. Teaching is essential to the growth and sustainability of our field as prospective students tend to discover CP during their undergraduate studies.

View Article and Find Full Text PDF

On August 17, 2017 at 12∶41:04 UTC the Advanced LIGO and Advanced Virgo gravitational-wave detectors made their first observation of a binary neutron star inspiral. The signal, GW170817, was detected with a combined signal-to-noise ratio of 32.4 and a false-alarm-rate estimate of less than one per 8.

View Article and Find Full Text PDF