421,546 results match your criteria: "University of Washington; and.[Affiliation]"

To discover the means of persuasion available to experts who embrace the responsibility of public communication in times of crisis, this study uses a text/countertext method of rhetorical analysis on U.S. newspaper editorials by scientists writing about COVID-19 policy.

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Lipid droplets (LDs) are the major sites of lipid and energy homeostasis. However, few LD biogenesis proteins have been identified. Using model microalga , we show that ABHD1, an α/β-hydrolase domain-containing protein, is localized to the LD surface and stimulates LD formation through two actions: one enzymatic and one structural.

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Celiac trunk angiography with balloon occlusion of splenic artery for diagnosis and treatment of splenic steal syndrome.

Radiol Case Rep

March 2025

University of Maryland School of Medicine, Department of Diagnostic Radiology and Nuclear Medicine, Division of Vascular and Interventional Radiology, Baltimore, MD, USA.

Splenic steal syndrome (SSS) post liver transplant is a potential cause of graft dysfunction in the setting of peripheral hepatic arterial bed resistance and redirection of blood flow to a dominant splenic artery resulting in reduction of hepatic arterial inflow. We report utilization of balloon occlusion of the proximal splenic artery as an objective measure to confirm the diagnosis of SSS in a patient with orthotopic liver transplant followed by successful treatment with proximal splenic artery embolization using Gelfoam and Amplatzer vascular plug. Written informed consent for the publication of this case report was obtained from the patient.

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Background: It is increasingly recognized that policies played a role in mitigating or exacerbating health inequities during the COVID-19 pandemic. While US counties were particularly active in policymaking, limited work has characterized geographic and temporal variation in pandemic-era policymaking at the local level, a prerequisite for later studies examining the health effects of these policies. This paper fills this gap by characterizing county-level COVID-19-related policy trajectories over time using a novel national policy database and innovative methods.

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Background: Alterations in cellular metabolism affect cancer survival and can manifest in metrics of body composition. We investigated the effects of various body composition metrics on survival in patients with glioblastoma (GBM).

Methods: We retrospectively analyzed patients who had an abdominal and pelvic computed tomography (CT) scan performed within 1 month of diagnosis of GBM (178 participants, 102 males, 76 females, median age: 62.

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Objectives: Despite progress in promoting gender equality, gender bias remains a significant obstacle for women and hinders their academic advancement. We aim to survey and critically analyze women's representation in conferences and changes over time in various regions of Asian countries.

Methods: An international survey was conducted with representatives from East Asia (Hong Kong, China, and Japan), South Asia (India and Pakistan), and Southeast Asia (Vietnam and Thailand).

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Coping and Social Support in Relation to Minority Stress and Cigarette Smoking Among Lesbian, Gay, and Bisexual Veterans.

Ann LGBTQ Public Popul Health

December 2024

Department of Health Systems and Population Health, University of Washington, School of Public Health, Seattle, WA, USA.

The intersection between a minoritized sexual orientation identity and a U.S. military Veteran status places lesbian, gay, and bisexual (LGB) Veterans at increased risk for cigarette smoking.

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Objective: To evaluate the pharyngeal airway dimensions and regional pharyngeal adipose distribution in the young adult minipig model.

Materials And Methods: Eight 7-8-months-old Yucatan minipigs, half male and female, were sedated and placed prone to scan the pharyngeal region. Magnetic resonance imaging (MRI) was performed using dynamic turbo-field echo (TFE)-sequence with respiratory gating and adipose-weighted sequence.

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Collaboration practices have been utilized within applied behavior analysis (ABA) to build relationships among relevant stakeholders. A recent focus within the field of ABA highlights collaborative practices for behavior analysts to utilize in service delivery positions. However, myriad barriers, such as sources of funding and competing stakeholder interests, inhibit behavior analysts' ability to build collaborative partnerships with families.

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Introduction: The 2018 Common Rule revision intended to improve informed consent by recommending a concise key information (KI) section, yet provided little guidance about how to describe KI. We developed innovative, visual KI templates with attention to health literacy and visual design principles. We explored end users' attitudes, beliefs, and institutional policies that could affect implementing visual KI pages.

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Introduction: Integrating community expertise into scientific teams and research endeavors can holistically address complex health challenges and grand societal problems. An in-depth understanding of the integration of team science and community engagement principles is needed. The purpose of this scoping review was to identify how and where team science and community engagement approaches are being used simultaneously in research.

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Introduction: There is increasing pressure on the federal research budget and shifting public opinions about the value of the academic enterprise. We must develop and apply metrics that demonstrate the broad benefits of research for health and society. The Translational Science Benefits Model (TSBM) measures the impact of large-scale translational science initiatives, such as the National Cancer Institute's Cancer Moonshot.

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Neurotechnological cognitive enhancement has become an area of intense scientific, policy, and ethical interest. However, while work has increasingly focused on ethical views of the general public, less studied are those with personal connections to cognitive impairment. Using a mixed-methods design, we surveyed attitudes regarding implantable neurotechnological cognitive enhancement in individuals who self-identified as having increased likelihood of developing dementia (n=25; 'Our Study'), compared to a nationally representative sample of Americans (n=4726; 'Pew Study').

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Background: Tricuspid valve surgical procedures (TVS) concomitant with mitral valve (MV) surgical procedures for less than severe tricuspid regurgitation (TR) remains controversial. This study examined the long-term outcomes of patients with moderate or mild to moderate TR undergoing MV surgical procedures with or without TVS.

Methods: Patients with moderate or mild to moderate TR undergoing MV replacement or repair between January 2002 and June 2021 were included.

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The Specialized Donor Care Facility Model Improves Operating Room Efficiency.

Ann Thorac Surg Short Rep

September 2024

Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Missouri.

Background: Organ procurement organizations coordinate organ donation through 2 distinct models of care: the conventional model, in which donors are managed at hospitals where brain death occurs, and the specialized donor care facility (SDCF) model, where brain dead donors are transferred to a freestanding facility. The aim of this study is to compare operating room efficiency for procurements between the SDCF and conventional models of care.

Methods: We performed a prospective analysis of operating room efficiency between thoracic donor procurement operations performed at a SDCF and other organ procurement organizations using the conventional model of care.

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Intelligent biology and medicine: Accelerating innovative computational approaches.

Comput Struct Biotechnol J

November 2024

Center for Precision Health, McWilliams School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.

In this editorial, we summarize the 2023 International Conference on Intelligent Biology and Medicine (ICIBM 2023) conference which was held on July 16-19, 2023 in Tampa, Florida, USA. We then briefly describe the nine research articles included in this special issue. ICIBM 2023 scientific program included four tutorials and workshops, four keynote lectures, four eminent scholars' presentations, 11 concurrent scientific sessions, and a poster session.

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Demographic and Clinical Characteristics of Mental Health Crisis Line Callers Who Were Transferred to 911.

Psychiatr Serv

January 2025

Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle (Goldman); Keck School of Medicine, University of Southern California, Los Angeles (Elser); Center for Health Policy and Health Services Research, Henry Ford Health, Detroit (Yeh, Ma, Ahmedani); Department of Psychology, University of Wisconsin, Madison (McDaniel); Department of Emergency Medicine, University of California San Francisco, San Francisco (Foster).

Objective: This study aimed to describe the characteristics of callers to a statewide mental health crisis line who were transferred to 911 (active rescue).

Methods: This retrospective cohort study examined mental health crisis line calls transferred to active rescue (N=3,538 calls; N=3,132 unique callers) from the Georgia Crisis and Access Line (2016-2018). Chi-square analyses and t tests were used to examine descriptive differences between caller characteristics and call features.

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Recent studies have demonstrated the ability to switch weakly coupled interlayer magnetic orders by using electric polarization in insulating van der Waals heterostructures. However, controlling strongly coupled intralayer magnetic orders remains a significant challenge. In this work, we propose that frustrated multiferroic heterostructures can exhibit enhanced intralayer magnetoelectric coupling.

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Guidance for an Effective Approach to Integrated Evidence Planning in a Dynamic World.

Clin Pharmacol Ther

January 2025

Boston Consulting Group, Zurich, Switzerland.

The value of a medicine is defined by its impact on patients, caregivers, health system, and society. A pharmaceutical company will generate evidence to demonstrate this value in various studies, including randomized clinical trials, non-interventional and observational studies, real-world data analyses, modeling, and simulation. The quality and strength of the evidence supporting a medicine's effectiveness, safety and product quality will drive decisions by healthcare system stakeholders for marketing authorization (regulatory authorities).

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Background: Seasonal influenza illness and acute respiratory infections can impose a substantial economic burden in low- and middle-income countries (LMICs). We assessed the cost of influenza illness and acute respiratory infections across household income strata.

Methods: We conducted a secondary analysis of data from a prior systematic review of costs of influenza and other respiratory illnesses in LMICs and contacted authors to obtain data on cost of illness (COI) for laboratory-confirmed influenza-like illness and acute respiratory infection.

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In vivo calcium imaging in freely moving rats using miniscopes provides valuable information about the neural mechanisms of behavior in real time. A gradient index (GRIN) lens can be implanted in deep brain structures to relay activity from single neurons. While such procedures have been successful in mice, few reports provide detailed procedures for successful surgery and long-term imaging in rats, which are better suited for studying complex human behaviors.

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Background: Chronic hepatitis C virus (HCV) infection affects >1% of the U.S. population, higher among U.

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Pregnancy Intendedness by Presence and Extent of Disability in the USA, 2019-2020.

Perspect Sex Reprod Health

January 2025

Institute on Development and Disability, School of Medicine, Oregon Health & Science University, Portland, Oregon, USA.

Context: Over 40% of pregnancies in the United States are unintended. Women with unintended pregnancies may be less likely to receive timely prenatal care and engage in healthy behaviors immediately before and during pregnancy. Limited research suggests that women with disabilities are more likely to have an unintended pregnancy, but to date no studies have assessed whether intendedness varies by extent of disability.

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Historically, it takes an average of 17 years to move new treatments from clinical evidence to daily practice. Given the highly effective treatments now available to prevent or delay kidney disease onset and progression, this is far too long. The time is now to narrow the gap between what we know and what we do.

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