Emotional literacy programme in special schools for children with a learning disability in England: the ZF-SEND feasibility RCT.

Background: Children with a learning disability experience a range of inequalities and adverse life events that put them at greater risk of mental health problems. The construct of emotional literacy has been shown to be a moderating factor of how life stress affects mental health. Teaching emotional literacy in schools may therefore be an effective way to promote positive mental health.

Interventions to improve mental health and well-being in care-experienced children and young people aged less than 25: the CHIMES systematic review.

Background: Children and young people with experience of being in care (e.g. foster care, kinship care, residential care or at home with a supervision requirement order) are at higher risk of adverse mental health and well-being outcomes compared to the general population.

Public health, policy, and clinical interventions to improve perinatal care for migrant women and infants in high-income countries: a systematic review.

Background: Migrant women who are pregnant or postpartum and their infants are often at increased risk of poorer perinatal outcomes compared to host country populations. This review aimed to identify public health, policy, and clinical interventions to improve maternity care for migrant women and their infants in high-income countries (HICs).

Methods: In this systematic review we searched EMBASE, EMCARE, MEDLINE and PsycINFO, CENTRAL, Scopus, CINAHL Plus, Web of Science, and grey literature from inception to 13th March 2024, with no language or date restrictions (PROSPERO: CRD42022380678).

Childhood interstitial lung disease survivors in adulthood: a European collaborative study.

Background: Interstitial lung disease (ILD) is rarer in children (chILD) than adults, but with increasing diagnostic awareness, more cases are being discovered. chILD prognosis is often poor, but increasing numbers are now surviving into adulthood.

Aim: To characterize chILD-survivors and identify their impact on adult-ILD centers.

Toward a global understanding of neonatal behaviour: adaptation and validation of the Neonatal Behavioural Assessment Scale (NBAS) in the UK and rural Gambia.

There is a need of expanding research on neonatal behaviour to encompass diverse global populations. However, few measures appropriate for use from birth in diverse cultural contexts exist. We present data from rural Gambia and the UK using the Neonatal Behavioural Assessment Scale (NBAS).

DAIR for periprosthetic joint infections-One week to save the joint?

Background: Predicting the success of a Debridement, Antibiotics, and Implant Retention (DAIR) procedure for periprosthetic joint infection (PJI) for hip and knee joint arthroplasty remains a challenge. A failed DAIR might adversely affect the outcome of any future revision surgery for PJI. Hence, the ability to identify and optimize factors predictive of DAIR success would help target the procedure to the appropriate patient cohort and avoid unnecessary surgery for patients where a DAIR is unlikely to eradicate infection.

Future-proofing tomorrow: achieving a unified vision through population health and multi-hazard early warning systems.

In this piece Nunes addresses the importance of population health approaches and Multi-Hazards Early Warning Systems (MHEWS) in public health, particularly considering climate change and its associated risks and hazards. The article aims to highlight the challenges posed by climate change to public health and how integrating MHEWS with population health approaches can help address these challenges effectively.

Growing challenge of multimorbidity in patients undergoing surgery.

As populations age, the incidence of multimorbidity rises, posing significant challenges for surgical and perioperative healthcare systems. Emerging evidence suggests multimorbidity can lead to worse patient outcomes. Healthcare providers must consider multimorbidity as a critical factor when planning surgical interventions with patients.

Protocol for a feasibility and acceptability study for UK general population paediatric type 1 diabetes screening-the EarLy Surveillance for Autoimmune diabetes (ELSA) study.

Aim: The EarLy Surveillance for Autoimmune (ELSA) study aims to explore the feasibility and acceptability of UK paediatric general population screening for type 1 diabetes.

Methods: We aim to screen 20,000 children aged 3-13 years for islet-specific autoantibodies through dried blood spot sample collection at home, hospital or community settings. Children with two or more autoantibodies are offered metabolic staging via oral glucose challenge testing.

Cationic Star Polymers Obtained by the Arm-First Approach─Influence of Arm Number and Positioning of Cationic Units on Antimicrobial Activity.

Recently, we published a study demonstrating the promising structure-activity relationship of 4-arm star polymers toward bacterial cells and biofilms. The aim of this study was to increase the number of arms to determine if this could further enhance activity via the arm-first approach, which enables access to star structures with a higher number of arms. A library of amphiphilic diblock and miktoarm star polymers was successfully synthesized, and their biological properties were assessed.

Maternal self-efficacy during infancy: Investigating the roles of depression and social support among mothers in rural Pakistan.

Maternal self-efficacy during infancy is shaped by many factors, including maternal mental health and social support. This study examines how depression, emotional support, and childcare support relate to maternal self-efficacy among mothers of infants in rural Pakistan. Participants included 885 mothers assessed at 3 and 6 months postpartum.

Conceptual framework for data harmonisation in mental health using the International Classification of Functioning, Disability and Health: an example with the R2D2-MH consortium.

Introduction: Advancing research and support for neurologically diverse populations requires novel data harmonisation methods that are capable of aligning with contemporary approaches to understanding health and disability.

Objectives: We present the International Classification of Functioning, Disability and Health (ICF) as a conceptual framework to support harmonisation of mental health data and present a proof of principle within the Risk and Resilience in Developmental Diversity and Mental Health (R2D2-MH) consortium.

Method: 138 measures from various mental health datasets were linked to the ICF following the WHO's established linking rules.

Post-operative periprosthetic femoral fractures in England: Patient profiles and short-term outcomes.

Background And Objective: Post-operative periprosthetic femoral fractures (POPFF) present a growing challenge for healthcare services, but there are limited national data on patient profiles, short-term outcomes, and post-discharge follow-up. We aimed to fill these gaps.

Methods: Using Hospital Episode Statistics (HES), we identified POPFF discharges from hospitals in England for patients aged 18 and above between April 2016 and December 2022.

Uptake and experience of professional interpreting services in primary care in a South Asian population: a national cross-sectional study.

Background: Interpreting services bridge language barriers that may prevent patients and clinicians from understanding each other, impacting quality of care and health outcomes. Despite this, there is limited up-to-date evidence regarding the barriers to and facilitators of uptake in primary care. The aim of this study was to ascertain current national uptake and experience of interpreting services in primary care (general practice) by South Asian communities in England.

The Association Between Periconceptual Maternal Dietary Patterns and Miscarriage Risk in Women With Recurrent Miscarriages: A Multicentre Cohort Study.

Objective: To examine the association between periconceptual maternal diet and miscarriage risk among women with recurrent miscarriages.

Design: Prospective multicentre cohort study (Tommy's Net).

Setting: Three university hospital research centres in the United Kingdom.

Early Economic Modeling to Inform a Target Product Profile: A Case Study of a Novel Rapid Test for Infection.

Unlabelled: Target product profiles (TPPs) specify the essential properties tests must have to be able to address an unmet clinical need. To explore how early economic modeling can help to define TPP specifications based on cost-effectiveness considerations using the example of a new rapid diagnostic for infection (CDI), a contagious health care-associated infection causing potentially fatal diarrhea. A resource-constrained simulation model was developed to compare a hypothetical test for CDI with current practice (i.

Atlas of the plasma proteome in health and disease in 53,026 adults.

Large-scale proteomics studies can refine our understanding of health and disease and enable precision medicine. Here, we provide a detailed atlas of 2,920 plasma proteins linking to diseases (406 prevalent and 660 incident) and 986 health-related traits in 53,026 individuals (median follow-up: 14.8 years) from the UK Biobank, representing the most comprehensive proteome profiles to date.