2 results match your criteria: "University of Verona Medical School and Azienda Ospedaliera di Verona[Affiliation]"
Insulin causes endothelial dysfunction in humans: sites and mechanisms.
Circulation
February 2002
Division of Endocrinology, Department of Biomedical and Surgical Sciences, University of Verona Medical School and Azienda Ospedaliera di Verona, Verona, Italy.
Article Synopsis
- The study investigates how hyperinsulinemia affects endothelial function in large arteries, which is important for understanding the risk of atherosclerosis in insulin-resistant individuals.
- Twenty-five healthy participants were subjected to various conditions of insulin levels, with assessments of both endothelium-dependent and independent vasodilation through ultrasound techniques.
- Results showed that hyperinsulinemia diminishes endothelium-dependent vasodilation but not endothelium-independent vasodilation, and the antioxidant vitamin C can restore endothelial function, suggesting oxidative stress may mediate these effects.
Prevalence of insulin resistance in metabolic disorders: the Bruneck Study.
Diabetes
October 1998
Division of Endocrinology and Metabolic Diseases, University of Verona Medical School and Azienda Ospedaliera di Verona, Italy.
The prevalence of insulin resistance in the most common metabolic disorders is still an undefined issue. We assessed the prevalence rates of insulin resistance in subjects with impaired glucose tolerance (IGT), NIDDM, dyslipidemia, hyperuricemia, and hypertension as identified within the frame of the Bruneck Study. The study comprised an age- and sex-stratified random sample of the general population (n = 888; aged 40-79 years).
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