1,647 results match your criteria: "University of Vermont Medical Center[Affiliation]"

Article Synopsis
  • Malalignment of the great toenails is a frequently overlooked nail disorder that is not often recognized in general medical practice.
  • The study reviewed 34 articles involving 117 patients, all exhibiting lateral deviation of the toenails along with yellow-brown discoloration and thickening.
  • The findings highlight the need for increased awareness among healthcare providers to improve diagnosis and management of this underdiagnosed condition.
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Although telehealth was a viable means of delivering psychiatric care even before the COVID-19 public health emergency, flexibilities at the federal and state levels during the pandemic prompted mass adoption in a short timeframe. Little is known about how psychiatrists plan to offer care going forward and to what degree services will be offered virtually, in-person, or in a hybrid format. We conducted a survey of American Psychiatric Association (APA) members regarding telepsychiatry practice and potential barriers.

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Background: The choice of transcatheter aortic valve replacement (TAVR) prosthesis is crucial in optimizing short- and long-term outcomes. The objective of this study was to conduct a meta-analysis comparing outcomes of third-generation balloon-expandable valves (BEV) vs self-expanding valves (SEV).

Methods: Electronic databases were searched from inception to June 2023 for studies comparing third-generation BEV vs SEV.

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Pericardial Diseases: International Position Statement on New Concepts and Advances in Multimodality Cardiac Imaging.

JACC Cardiovasc Imaging

August 2024

Department of Medicine, University of Udine, Udine, Italy; Cardiothoracic Department, University Hospital Santa Maria della Misericordia, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.

Pericardial diseases have gained renewed clinical interest, leading to a renaissance in the field. There have been many recent advances in pericardial diseases in both multimodality cardiac imaging of diagnoses, such as recurrent, transient constrictive and effusive-constrictive pericarditis, and targeted therapeutics, especially anti-interleukin (IL)-1 agents that affect the inflammasome as part of autoinflammatory pathophysiology. There remains a large educational gap for clinicians, leading to variability in evaluation and management of these patients.

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Context.—: Laboratory testing practices for diagnosis of Clostridioides difficile infection (CDI) have evolved in response to published guidelines, availability of highly sensitive nucleic acid amplification tests (NAATs), perceived problems with the specificity of NAATs, and CDI reporting requirements.

Objective.

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Article Synopsis
  • Mohs micrographic surgery (MMS) is an effective treatment for melanoma in situ (MIS), but inconsistent surgical techniques make it hard to apply current data broadly.
  • To standardize MMS techniques for MIS in future studies, a modified Delphi method was used, involving expert input through voting on various surgical approaches.
  • The study generated 8 consensus recommendations, with five agreed upon in the first round and the others in the second, aimed at providing uniform guidelines to improve future clinical trials.
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In this study, we describe the role of ultrasound in diagnosing pediatric peritonsillar abscesses (PTAs). A retrospective chart review was conducted on 54 children aged 4 to 17 years who had an ultrasound performed for suspected PTA. Based on ultrasound imaging, the patients were classified into 2 groups: PTA-positive (8, 14.

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Article Synopsis
  • - The Intensive Care Medicine Rapid Practice Guideline (ICM-RPG) provides evidence-based recommendations for using small-volume versus conventional blood collection tubes in adult ICU patients.
  • - A systematic review of 23 panelists across 8 countries revealed high certainty that small-volume tubes minimize blood sampling volume and show moderate certainty in reducing transfusion risks, despite some imprecision in the data.
  • - The panel strongly recommends small-volume tubes due to their benefits, including reduced waste and successful implementation in various countries, although there are initial costs related to validating these tubes for laboratory use.
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The publication of Clinical and Laboratory Standards Institute's guideline H62 has provided the flow cytometry community with much-needed guidance on development and validation of flow cytometric assays (CLSI, 2021). It has also paved the way for additional exploration of certain topics requiring additional guidance. Flow cytometric analysis of rare matrices, or unique and/or less frequently encountered specimen types, is one such topic and is the focus of this manuscript.

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Background: Rilonacept inhibits the interleukin-1 pathway, and extended treatment in patients with recurrent pericarditis (RP) reduced recurrence risk by 98% in the phase 3 trial, RHAPSODY long-term extension (LTE). Severe acute respiratory syndrome (SARS)-CoV-2 vaccination and/or infection may trigger pericarditis recurrence, and in clinical practice, it is unknown whether to continue rilonacept during SARS-CoV-2 infection. This post-hoc analysis of the RHAPSODY LTE aimed to inform rilonacept management in RP patients vaccinated against SARS-CoV-2 or who contract COVID-19.

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Article Synopsis
  • Klinefelter syndrome is a genetic condition characterized by the presence of an extra X chromosome (47,XXY), occurring in about 1 in 600 male births, while a rarer combination with some 46,XX cells also exists.
  • A study analyzed the clinical records of 34 patients with this unique karyotype across 14 medical institutions, finding significant variability in symptoms and the proportion of XX cells in their samples.
  • The research concluded that clinical manifestations are highly diverse, which complicates treatment, and emphasized the importance of using advanced genetic testing methods to accurately identify the condition due to potential mosaicism.
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Introduction: Pediatric head and neck (HN) trauma is an important contributor to pediatric morbidity, resulting in significant downstream consequences. Few studies provide epidemiological predictors of pediatric HN trauma on a national scale. The present study aims to identify risk factors of HN injury and mortality in the pediatric population.

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Acute kidney injury in subarachnoid hemorrhage: Exploring its clinical significance and prognostic implications.

J Stroke Cerebrovasc Dis

September 2024

Department of Neurology, Westchester Medical Center, Valhalla, NY, USA; Department of Neurosurgery, Westchester Medical Center, Valhalla, NY, USA. Electronic address:

Article Synopsis
  • The study investigates the link between acute kidney injury (AKI) and outcomes in patients with spontaneous subarachnoid hemorrhage (SAH), a serious condition with a high risk of complications.
  • An analysis of over 76,000 SAH patients from 2010 to 2019 shows that about 14% developed AKI, with these patients being older and more likely to be obese compared to those without AKI.
  • Findings indicate that AKI is significantly associated with poorer functional outcomes, longer hospital stays, and higher in-hospital mortality, highlighting the need for early detection to improve recovery chances.
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The Impact of Large Language Model-Generated Radiology Report Summaries on Patient Comprehension: A Randomized Controlled Trial.

J Am Coll Radiol

December 2024

Department of Radiology, Larner College of Medicine at the University of Vermont, Burlington, Vermont; ACR Delegate to the American Medical Association House of Delegates; Division Chief Ultrasound Imaging, Director of CM; Associate Program Director Diagnostic Radiology Residency. Electronic address: https://twitter.com/NaiimAli.

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Factors Associated with Delays in Initiating Biologic Therapy in Patients with Inflammatory Bowel Disease.

Dig Dis Sci

August 2024

Center for Inflammatory Bowel Diseases, Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave., Boston, MA, 02215, USA.

Article Synopsis
  • - The study highlights that quick initiation of biologic therapy is crucial for patients with inflammatory bowel disease (IBD), but various factors can delay this process in an outpatient setting.
  • - Researchers analyzed data from 411 patients receiving biologics between March 2019 and September 2020, finding an overall median delay of 20 days, with specific delays varying by medication.
  • - Key factors contributing to delays included being self-identified as Black, living farther from treatment facilities, and not having immediate insurance coverage approval.
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Background/objectives: Ambulatory thromboprophylaxis (AT) in patients with pancreatic adenocarcinoma (PAC) reduces venous thromboembolism (VTE) risk and is recommended for patients receiving systemic chemotherapy. We evaluated VTE rates, severity, timing, and risk factors in PAC patients as well as AT rates and initiation times.

Methods: Patients diagnosed with PAC were included.

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Background: Multiple guidelines recommend assessment of bleeding and venous thromboembolism (VTE) risk in adult medical inpatients to inform prevention strategies. There is no agreed-upon method for VTE and bleeding risk assessment.

Objectives: To validate the International Medical Prevention Registry on Venous Thromboembolism (IMPROVE) VTE and bleeding risk scores in an independent population.

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Objective criteria are required for prostate cancer (PCa) risk assessment, treatment decisions, evaluation of therapy, and initial indications of recurrence. Circulating microRNAs were utilized as biomarkers to distinguish PCa patients from cancer-free subjects or those encountering benign prostate hyperplasia. A panel of 60 microRNAs was developed with established roles in PCa initiation, progression, metastasis, and recurrence.

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