Soft molecularly imprinted nanoparticles with simultaneous lossy mode and surface plasmon multi-resonances for femtomolar sensing of serum transferrin protein.

The simultaneous interrogation of both lossy mode (LMR) and surface plasmon (SPR) resonances was herein exploited for the first time to devise a sensor in combination with soft molecularly imprinting of nanoparticles (nanoMIPs), specifically entailed of the selectivity towards the protein biomarker human serum transferrin (HTR). Two distinct metal-oxide bilayers, i.e.

Correspondence Between Values of Vertical Loading Rate and Oxygen Consumption During Inclined Running.

Purpose: The aim of this study was to provide a theoretical model to predict the vertical loading rate (VLR) at different slopes and speeds during incline running.

Methods: Twenty-nine healthy subjects running at least once a week performed in a randomized order 4-min running trials on an instrumented treadmill at various speeds (8, 10, 12, and 14 km h) and slopes (- 20%, - 10%, - 5%, 0%, + 5%, + 10%, + 15%, + 20%). Heart rate, gas exchanges and ground reaction forces were recorded.

History of cannabis and the endocannabinoid system .

This article retraces the story of cannabis from the earliest contacts of humans with the plant to its subsequent global expansion, its medicinal uses, and the discovery of the endocannabinoid system in the 20 century. Cannabis was attested to around 12 000 years ago near the Altai Mountains in Central Asia, and since then, cannabis seeds have accompanied the migration of nomadic peoples. Records of the medicinal use of cannabis appear before the Common Era in China, Egypt, and Greece (Herodotus), and later in the Roman empire (Pliny the Elder, Dioscorides, Galen).

Current status on aortic endografts.

Endovascular treatment has become widespread to treat aneurysmal disease, especially located in the aorta. The modern era of abdominal aortic aneurysm repair started between 1986 and 1991, and in the last 30 years, Endovascular Treatment for abdominal aortic aneurysms evolved both due to the development of new materials and devices and the increasing appeal and effectiveness of the endovascular therapy itself. Vascular surgeons are using nowadays different solutions of Endovascular Treatment to treat all the expressions of aortic pathology (aneurysms, dissections and trauma) both in the acute and elective setting.

Lignosulfonate Salt Tolerance and the Effect on Emulsion Stability.

In this article, we adapted and compared methods to assess lignosulfonates for technical applications. Salt-induced agglomeration and precipitation were studied via mechanical separation and subsequent UV spectrometry. The effect of lignosulfonates on emulsion stability was investigated in two steps: measuring the amount of oil separated after centrifugation and subjecting the remaining emulsion to shear in a rheometer.

Syntheses and analytical characterizations of novel (2-aminopropyl)benzo[b]thiophene (APBT) based stimulants.

Two groups of amphetamine-like drugs with psychostimulant properties that were first developed during the course of scientific studies and later emerged as new psychoactive substances (NPS) are based on the (2-aminopropyl)indole (API) and (2-aminopropyl)benzofuran (APB) structural scaffolds. However, sulfur-based analogs with a benzo[b]thiophene structure (resulting in (2-aminopropyl)benzo[b]thiophene (APBT) derivatives) have received little attention. In the present investigation, all six racemic APBT positional isomers were synthesized in an effort to understand their structure-activity relationships relative to API- and APB-based drugs.

Sustainable metropolitan areas perspectives through assessment of the existing waste management strategies.

Human activities are considered among the main producers of any kind of pollution. This paper, through a Driver-Pressure-State-Impact-Response (DPSIR) model analyses, focuses on the evaluation and assessment of the existing practices, procedures, and results obtained in order to determine whether the municipal solid waste (MSW) management implemented in three major Greek municipalities in the greater urban area of Attica, namely the municipalities of Nea Smirni, Vyronas, and Piraeus, could be considered viable and sustainable. The evaluation indicated that MSW in Greek cities have reduced over the last years, also suggesting a steady downward trend, which could be considered consistent with that of the per capita incomes in Greece due to the extended economic austerity, while at the same time the recycling indicator seems to optimize.

Enhanced GROMACS: toward a better numerical simulation framework.

The GROMACS software package represented a promising direction toward the molecular dynamic simulation and there is ongoing interest to extend it. In this study, we introduce a new component into the conventional package with the goal being to facilitate the process of finding the native structure of proteins with minimal free-energy value. We achieved this through incorporating a wide range of metaheuristic optimization algorithms and force fields, leading up to the EGROMACS molecular simulation toolkit.