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The purpose of this study was to develop and validate cardiac computed tomog-raphy (CT) quantitative analysis software with a patient-specific, 17-segment myocardial model that uses electrocardiogram (ECG)-gated cardiac CT images to differentiate between normal controls and severe aortic stenosis (AS) patients. ECG-gated cardiac CT images from 35 normal controls and 144 AS patients were semiautomatically segmented to create a patient-specific, 17-segment myocardial model. Two experts then manually determined the anterior and posterior interven-tricular grooves to be boundaries between the 1st and 2nd segments and between the 3rd and 4th segments, respectively, to correct the model.

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