Experimental exposure of bivalves (Ruditapes decussatus) and meiobenthos (Metoncholaimus pristiurus) to 2,2'4,4'-tetrabromodiphenyl ether (PBDE-47) assessed by biochemical, computational modeling, and microbial tools.

PBDE-47, with lipophilic properties, was found in mussels, clams, and fish where it causes developmental issues, and endocrine and immune disruptions. The current study investigated the effects of PBDE-47 (0.1, 1, and 10 μg.

NEOADJUVANT TREATMENT OF LIVER METASTASES OF COLORECTAL CANCER: PREDICTIVE FACTORS OF PATHOLOGICAL RESPONSE.

Background: Surgery after neoadjuvant chemotherapy (CT) improves the prognosis of colorectal liver metastases (CRLM).

Aims: The aim of this study was to evaluate the predictive factors of the histological response of CRLM after neoadjuvant treatment.

Methods: A retrospective monocentric study including patients with CRLM operated after neoadjuvant treatment.

Desmoid-type fibromatosis in an uncommon location: A case report of shoulder involvement misdiagnosed as rhabdomyosarcoma.

Introduction And Importance: Desmoid-type fibromatosis is an uncommon tumor characterized by its local invasiveness, with shoulder involvement being notably infrequent. The optimal treatment strategy for this tumor remains a topic of ongoing debate.

Case Presentation: A 47-year-old Tunisian woman with a history of hypothyroidism, presented with pain and swelling in her left shoulder for a year.

UAV Trajectory Tracking Using Proportional-Integral-Derivative-Type-2 Fuzzy Logic Controller with Genetic Algorithm Parameter Tuning.

Unmanned Aerial Vehicle (UAV)-type Quadrotors are highly nonlinear systems that are difficult to control and stabilize outdoors, especially in a windy environment. Many algorithms have been proposed to solve the problem of trajectory tracking using UAVs. However, current control systems face significant hurdles, such as parameter uncertainties, modeling errors, and challenges in windy environments.

Disease Activity in Pregnant and Postpartum Women With Multiple Sclerosis Receiving Ocrelizumab or Other Disease-Modifying Therapies.

Background And Objectives: Women with multiple sclerosis (MS) are at risk of disease reactivation in the early postpartum period. Ocrelizumab (OCR) is an anti-CD20 therapy highly effective at reducing MS disease activity. Data remain limited regarding use of disease-modifying therapies (DMTs), including OCR, and disease activity during peripregnancy periods.

Factors influencing valproic acid trough levels in epileptic children.

Objective: In this study, we aimed to assess main factors influencing the Valproic Acid (V.Acid) plasma trough levels (C0) and to determine their degree of influence on V.Acid C0 in children with epilepsy who had Therapeutic Drug Monitoring (TDM).

[Not Available].

Introduction: Virtual reality is being used more and more in the healthcare field, particularly during treatment. In the context of pain management, the question arises as to the effectiveness of using virtual reality during care in reducing the perception of procedural pain.

Aim: To study the impact of using virtual reality on the perception of procedural pain and on the course of care in pediatric oncology.

[Not Available].

Introduction: Audiovisual distraction (AVD) is one of the non-pharmacological means of anxiety prevention. However, few studies have evaluated its perioperative effect in adults.

Aim: To evaluate the contribution of audio-visual distraction in the prevention of perioperative anxiety in adult patients proposed for surgery under spinal anesthesia.

GAIA therapeutic farm: Prospective study on multidisciplinary care efficacy.

Introduction: The therapeutic farm "GAIA" in Sidi Thabet is a non-profit organization created in 2009, situated in the North-Western suburbs of the capital Tunis/Tunisia. Its main aims are the day-care for and the socio-professional integration of children and young adults between age 6 and 30 with diverse types of disability through multiple activities, such as pet assisted therapy and horticulture.

Aim: to assess the potential benefits of therapeutic on-farm management.

[Not Available].

Introduction: Several non-invasive tests (NIT) have been reported for predicting liver fibrosis to avoid percutaneous liver biopsy (PLB).

Aim: To evaluate the performance of NIT in Tunisian patients with chronic hepatitis B (CHB).

Methods: We calculated the ASAT/platelet ratio index (APRI), GGT-to-platelet ratio (GPR), Fibrosis-4 score (FIB-4), and RDW/platelet ratio (RPR).

Bill Length of Non-breeding Shorebirds Influences the Water Depth Preferences for Foraging in the West Coast of India.

Body size, bill length and shape determine foraging techniques, habitat selection and diet among shorebirds. In this study, water depth preferences of different shorebirds with different bill sizes in various habitats including mudflats, mangroves at Kadalundi-Vallikkunnu Community Reserve (KVCR) (19 shorebird species) and adjacent agroecosystems at Vazhakkad (12 species) were studied between 2017 and 2020. The bill length of the shorebirds was significantly and positively associated with the average water depth, where shorebirds were observed to forage.

Tremor Ataxia With Central Hypomyelation Phenotype Related to a Recurrent POLR3A Mutation in Six Unrelated Tunisian Families.

Background: POLIII-related leukodystrophies are a group of recently recognized hereditary white matter diseases with a similar clinical and radiological phenotype. No Tunisian studies have been published about POLIII-related leukodystrophy due to POLR3A variants. The aim of this study was to contribute to the clinical, radiological, and genetic characterization of POLR3A-related leukodystrophy in a Tunisian cohort.

Elevated Interleukin-21 expression is correlated with systemic sclerosis' severity in Tunisian patients.

Systemic sclerosis (SSc), a rare and lethal autoimmune disorder where patients presents diverse clinical features, therefore unravelling a potential biomarker within a specific cohort is crucial for improving patient care, especially for rare diseases. This study sought to identify potential biomarkers in Tunisian SSc patients. Gene expression analysis of interleukins (IL)-21 and IL-22 in peripheral blood mononuclear cells, using quantitative real-time polymerase chain reaction (qrt-pcr), revealed upregulated IL-21 and downregulated IL-22 in SSc patients compared to healthy controls.

Structure-Function Relationship of a Novel MTX-like Peptide (MTX1) Isolated and Characterized from the Venom of the Scorpion .

Maurotoxin (MTX) is a 34-residue peptide from venom. It is reticulated by four disulfide bridges with a unique arrangement compared to other scorpion toxins that target potassium (K) channels. Structure-activity relationship studies have not been well performed for this toxin family.

First principles approach and experimental exploration of a new double perovskite phase Sr(In SnSb)O: evaluation of structural, optical, and dielectric properties.

A new double perovskite phase, Sr(SnSbIn)O, was successfully synthesized a solid-state reaction and comprehensively characterized using both experimental and theoretical techniques. Powder X-ray diffraction was used to determine the crystal structure, while scanning electron microscopy (SEM) revealed a high degree of densification and uniform grain distribution across the ceramic. Raman and Fourier-transform infrared (FTIR) absorption spectra of the powder present broad bands predominantly due to different stretching modes of the various SnO , InO and SbO octahedra in the region = 400-800 cm.