Intestinal tuberculosis complicated with perforation in an immunocompetent patient: Case report and review of the literature.

Introduction: Intestinal tuberculosis (ITB), a rare yet severe manifestation of infection, poses significant diagnostic and therapeutic challenges due to its nonspecific clinical presentation. Perforation, a life-threatening complication, necessitates prompt surgical intervention and effective antituberculous therapy.

Case Presentation: This case study highlights a 41-year-old immunocompetent male who presented with fever, abdominal pain, vomiting, and significant weight loss.

Cost-effectiveness of human papillomavirus (HPV) vaccination in Tunisia: a modelling study.

Objectives: The objective of this study is to assess the cost utility of the implementation of the human papillomavirus (HPV) vaccination programme in Tunisia in addition to the current cytology screening strategy. This study is very important to guide health policy decision-makers and to help them allocate their scarce healthcare resources.

Design: We used a previously described Markov model on the Online Cost Effectiveness Analysis tool programmed with R Software.

Congenital portosystemic shunts: experience of a tertiary Tunisian referral center.

Congenital portosystemic shunt is a rare condition in which communications between the systemic venous circulation and the portal veins drain blood directly into the systemic circulation. Diagnosis may occur from the prenatal period to adulthood. Nevertheless, diagnosing and treating a congenital portosystemic shunt, particularly in the perinatal stage, remain challenging, as multiple complications can occur.

Congenital heart disease: Epidemiological, genetic and evolutive profil.

Introduction: Congenital heart disease is a heterogeneous group of malformations and one of the most common causes of mortality in children.

Aim: The aim of this study was to investigate the clinical, genetic and evolutive characteristics of congenital heart disease.

Methods: A retrospective, descriptive study was carried out between 2020 and 2023 at the pediatrics and neonatology department of Mongi Slim university hospital of Tunis.

Key Guidelines for Responding to Reviewers.

Background: The process of preparing a scientific manuscript is intricate, encompassing several critical stages, including pre-writing, research development, drafting, peer review, editing, publication, dissemination, and access. Among these, the peer review process (PRP) stands out as a pivotal component requiring seamless collaboration among editors, reviewers, and authors. Reviewers play a crucial role in assessing the manuscript's quality and providing constructive feedback, which authors must adeptly navigate to enhance their work and meet journal standards.

Routine CSF parameters as predictors of disease course in multiple sclerosis: an MSBase cohort study.

Background: It remains unclear whether routine cerebrospinal fluid (CSF) parameters can serve as predictors of multiple sclerosis (MS) disease course.

Methods: This large-scale cohort study included persons with MS with CSF data documented in the MSBase registry. CSF parameters to predict time to reach confirmed Expanded Disability Status Scale (EDSS) scores 4, 6 and 7 and annualised relapse rate in the first 2 years after diagnosis (ARR2) were assessed using (cox) regression analysis.

A qualitative study about critical appraisal of medical literature learning among medical students.

Introduction: Skills in critical appraisal of medical literature are compulsory to achieve in medical practice. This step is the third step of the evidence-based medicine process whose main role is to bridge a gap between scientific evidence and practice. Acquiring skills in critical appraisal of the literature has been reported to be challenging for the trainees with different limits according to their levels, backgrounds or specialties.

Is critical thinking potential correlated to critical appraisal skills of medical literature?

Introduction: Critical appraisal of medical literature is a mandatory skill to practice evidence-based medicine. The relation between the critical appraisal skills and the critical thinking potential has been rarely assessed in the literature.

Aim: To assess the relation of critical thinking potential to critical appraisal of medical literature competencies.

A case report of intestinal acute intussusception secondary to a lipoma: Imagery has a great value.

Introduction: Acute intestinal intussusception (AII) in adults, unlike in children, is a rare manifestation that is frequently secondary to malignant or benign tumors and intestinal intussusception on a lipoma is more exceptional.

Case Presentation: We present a rare case of AII caused by a lipoma in a previously healthy 44-year-old man. He experienced severe right lower quadrant pain and constipation.

A cadaveric anatomical study of the adrenals: vascular relationship.

The adrenal gland is a retroperitoneal organ with intimate relationships with neighboring organs but also with the large retroperitoneal vessels. Our aim was to study the vascular relationships of the adrenal gland with the large abdominal vessels. Our work is an anatomical dissection of 80 fresh cadaveric adrenals.

Incidental Finding of Arteria Lusoria in COVID-19 Patient with Aortic Thrombus Complicated by Recurrent Limb Ischemia.

Coronavirus disease causes a hypercoagulable state with endothelial inflammation. These conditions can produce embolic complications. Thrombosis can occur in different locations and may lead to ischemic stroke and ischemic limb.

Adrenal neuroblastoma in three year old boy, mistaken for pancreatic tumor: A case report.

Neuroblastoma is the most common extracranial solid tumor in children, often manifests in the retroperitoneal region. We present a case of a 3-year-old boy with no previous medical history, presented for abdominal distension. Physical examination revealed a distinct, mobile, solid mass situated in the left lumbar region.

Unusual cause of cerebral calcifications in an 8-year-old girl.

Key Clinical Message: Genetic counseling and genetic screening for hyperoxaluria should be recommended for children with urinary lithiasis for early management to avoid progression to oxalosis especially if there is a family history of lithiasis.

Unlabelled: Primary hyperoxaluria type 1 (PH1) is caused by a deficiency of the liver peroxisomal enzyme alanine-glyoxylate aminotransferase (AGT) resulting in overproduction of calcium oxalates. In its later stage, a systemic deposit of calcium oxalates is observed.

Type II pleuropulmonary blastoma mistaken for rhabdomyosarcoma: A case report.

Introduction: Pleuropulmonary blastoma (PPB) is rare, representing 0.3 % of all pediatric cancers. PPB is classified into three subtypes and may progress from type I to types II and III, with a worse prognosis.

Are biopsies during endoscopic ultrasonography necessary for a suspected esophageal leiomyoma? Is laparoscopy always feasible?

The present letter to the editor is related to the work entitled "Large leiomyoma of lower esophagus diagnosed by endoscopic ultrasonography-fine needle aspiration: A case report." Although endoscopic ultrasonography seems necessary in a suspected leiomyoma of the esophagus, the performance of biopsies fine needle aspiration is controversial as it increases the risk of complications such as bleeding, infection, and intraoperative perforations. Laparoscopy is the best treatment strategy for small tumors.

Severe infections in patients with systemic lupus erythematosus from Tunisia: Prevalence and risk factors.

Since the improvement in management and the reduction of mortality caused by the disease activity, infections have represented the main cause of morbidity and mortality in systemic lupus erythematosus patients. We aimed to determine the prevalence and identify risk factors of severe infections in systemic lupus erythematosus patients. We conducted a retrospective study on 93 Tunisian lupus patients followed between 2010 and 2019.

Cribriform-morular thyroid carcinoma: A case report with review of the literature.

Cribriform-morular thyroid carcinoma (CM-TC) is a rare entity that usually occurs in association with familial adenomatous polyposis (FAP) but may be sporadic. Herein, we present a new case of cribrifom-morular thyroid carcinoma occurring in a 28-year-old woman with no history of FAP.

The concept of telemedicine in pediatric rheumatology in Tunisia: Parents' perceptions.

Introduction: With the COVID-19 pandemic, health care systems are facing challenges in delivering proper patient care. Children and adolescents with juvenile idiopathic arthritis require specialized and comprehensive attention. In this context, telemedicine is an alternative that has the potential to improve access to healthcare in addition to cost savings.

Benign peritoneal cystic mesothelioma mimicking peritoneal tuberculosis.

In immunodeficient patients with repetitive peritoneal aggression, cystic mesothelioma should be considered as a differential diagnosis to peritoneal tuberculosis that must be ruled out in endemic countries.