2 results match your criteria: "University of Trieste and ASUGI[Affiliation]"
Statin-Intolerant Patients Exhibit Diminished Muscle Strength Regardless of Lipid-Lowering Therapy.
J Clin Med
February 2025
Unità Clinica Operativa Clinica Medica, Department of Medical, Surgical and Health Sciences, Faculty of Medicine, University of Trieste and ASUGI, 34149 Trieste, Italy.
Statin-associated muscle symptoms (SAMS) is a frequent side effect of statin therapy, limiting its clinical use and increasing cardiovascular risk. Its relationship with muscle performance and quality is not completely understood. The aim of our study was to retrospectively assess the differences between body composition and muscle strength in patients with SAMS, compared with matched controls.
View Article and Find Full Text PDFEpidemiology of atherosclerotic cardiovascular disease in polygenic hypercholesterolemia with or without high lipoprotein(a) levels.
Front Cardiovasc Med
January 2024
U.C.O. Clinica Medica, Department of Medical, Surgical and Health Sciences, University of Trieste and ASUGI, Trieste, Italy.
Article Synopsis
- The study investigates the differences in cardiovascular disease occurrence between patients with polygenic hypercholesterolemia who have high levels of Lp(a) (H-Lpa) versus those with polygenic hypercholesterolemia alone (H-LDL).
- A retrospective analysis of 258 H-Lpa patients and 290 H-LDL patients revealed that those with high Lp(a) experienced vascular events more frequently and at a younger age despite similar LDL cholesterol reductions.
- Men with H-Lpa showed a significantly higher risk of acute coronary artery disease, while women with H-Lpa faced a higher incidence of peripheral artery disease linked to smoking.